公开(公告)号：EP2930244A1

公开(公告)日：2015-10-14

申请号：EP14163770.2

申请日：2014-04-07

申请人： The Procter & Gamble Company

发明人： Xu, Jun ,  Saunders, Charles ,  Green, Phillip ,  Velasquez, Juan

IPC分类号： C12P19/26 ,  C12P7/42 ,  C12P7/52 ,  C12P7/62

CPC分类号： C12P7/52 ,  C12N9/1096 ,  C12P7/18 ,  C12P7/24 ,  C12P7/42 ,  C12Y104/01005 ,  C12Y104/03002 ,  C12Y206/01001 ,  C12Y206/01002

摘要： The invention relates to a micro-organism that is able to convert homoserine to 3-hydroxypropionaldehyde, wherein the micro-organism expresses a protein capable of converting homoserine to 2-keto-4-hydroxybutyrate wherein the protein is selected from the group consisting of: aminotransferases, an amino acid oxidases, and amino acid dehydrogenases.

摘要翻译： 本发明涉及一种微生物确实能够高丝氨酸转化为3-羟基丙醛，worin微生物快车能够将高丝氨酸为2-酮-4-羟基丁酸酯组成的蛋白质worin将蛋白质从所述组包括选自： 转氨酶氨基酸氧化酶和氨基酸脱氢酶。

公开(公告)号：EP1136550B1

公开(公告)日：2004-12-15

申请号：EP99917154.9

申请日：1999-04-23

申请人： International Reagents Corporation

发明人： BABA, Toshiyuki Int. Reagents Corp. ,  TABATA, Hiromasa Int. Reagents Corp. ,  NAGAMATSU, Katashi Int. Reagents Corp. ,  WATAZU, Yoshifumi Int. Reagents Corp. ,  AOKI, Ryoji Asahi Chemical Industry Co., Ltd.

IPC分类号： C12N9/96 ,  C12N9/10

CPC分类号： C12Y206/01021 ,  C12N9/1096 ,  C12N9/96 ,  C12Y206/01001 ,  C12Y206/01002

摘要： A method aiming at accurately and stably effecting medical examinations with the use of aspartate aminotransferase or alanine aminotransferase by stabilizing the aspartate aminotransferase or alanine aminotransferase in media. Valine and proline are added to the media (serum, buffer, etc.) as a component for stabilizing aspartate aminotransferase or alanine aminotransferase contained therein.

公开(公告)号：EP1427450A2

公开(公告)日：2004-06-16

申请号：EP02806826.0

申请日：2002-07-26

申请人： Mirus Corporation

发明人： LEWIS, Dave

IPC分类号： A61K48/00 ,  C07H21/04 ,  C12Q1/68

CPC分类号： C12N15/1137 ,  A61K31/58 ,  A61K31/74 ,  A61K38/00 ,  A61K48/00 ,  C12N15/111 ,  C12N15/88 ,  C12N2310/14 ,  C12N2320/32 ,  C12N2710/24111 ,  C12Y206/01002 ,  A61K2300/00

摘要： Described is a process for delivering an inhibitor directed against an expressible nucleic acid sequence in a mammal to inhibit RNA function. An RNA function inhibiting sequence that is specific to the expressible nucleic acid sequence in the mammal is made and inserted into a blood vessel in the mammal. The inhibitor is delivered to a cell wherein expression of the nucleic acid sequence is inhibited.

公开(公告)号：EP1968372B1

公开(公告)日：2012-02-08

申请号：EP06847950.0

申请日：2006-12-21

申请人： Arcadia Biosciences Inc.

发明人： GOOD, Allen, G. ,  DEPAUW, Mary ,  SHRAWAT, Ashok, K.

IPC分类号： C12N15/82 ,  A01H5/00

CPC分类号： C12N15/8261 ,  C07K14/415 ,  C12N9/1096 ,  C12N15/8227 ,  C12Y206/01002 ,  Y02A40/146

摘要： Methods are provided by which Oryza sativa plants and seeds thereof may be modified to express a coding region of interest using a promoter sequence operatively linked to the coding region. The promoter sequence is an isolated Oryza sativa antiquitin (OsAnt1) promoter sequence including SEQ ID NO: 1. The coding region of interest may encode a nitrogen utilization protein, suitably alanine aminotransferase. Methods to develop Oryza sativa plants that have increased biomass and seed yield are also presented. Furthermore, Oryza sativa plants may be produced that maintain a desired yield while reducing the need for high levels of nitrogen application.

公开(公告)号：EP1636385A4

公开(公告)日：2010-06-02

申请号：EP04776998

申请日：2004-06-24

申请人： MIRUS BIO CORP

发明人： LEWIS DAVID L ,  SPENCER ANDREW G ,  WOLFF JON A ,  HAGSTROM JAMES E ,  HERWEIJER HANS ,  LOOMIS AARON G

IPC分类号： C12Q1/68 ,  A01N43/04 ,  A61K20060101 ,  A61K31/07 ,  C07H21/04 ,  C12N15/11 ,  C12N15/113

CPC分类号： A61K31/07 ,  C07K14/005 ,  C12N15/111 ,  C12N15/1131 ,  C12N15/1137 ,  C12N15/1138 ,  C12N2310/11 ,  C12N2310/14 ,  C12N2310/3233 ,  C12N2320/31 ,  C12N2320/32 ,  C12N2730/10122 ,  C12Y101/01034 ,  C12Y206/01002

公开(公告)号：EP2186905A1

公开(公告)日：2010-05-19

申请号：EP08792251.4

申请日：2008-08-06

申请人： Chugai Seiyaku Kabushiki Kaisha

发明人： TABUCHI, Hisahiro ,  SUGIYAMA, Tomoya

IPC分类号： C12P21/00 ,  C12N1/15 ,  C12N1/19 ,  C12N1/21 ,  C12N5/10 ,  C12N9/10 ,  C12N15/09

CPC分类号： C07K16/28 ,  C07K14/47 ,  C12N9/1096 ,  C12P21/02 ,  C12Y206/01002 ,  Y02P20/52

摘要： The present invention provides a method capable of producing a natural or recombinant protein in high yield.
The present invention relates to a method of producing a polypeptide, comprising culturing a cell which strongly expresses alanine aminotransferase and has a transferred DNA encoding a desired polypeptide and thereby allowing the cell to produce the polypeptide.

公开(公告)号：EP1968372A2

公开(公告)日：2008-09-17

申请号：EP06847950.0

申请日：2006-12-21

申请人： Arcadia Biosciences Inc.

发明人： GOOD, Allen, G. ,  DEPAUW, Mary ,  SHRAWAT, Ashok, K.

IPC分类号： A01H1/00 ,  A01H5/00

CPC分类号： C12N15/8261 ,  C07K14/415 ,  C12N9/1096 ,  C12N15/8227 ,  C12Y206/01002 ,  Y02A40/146

摘要： Methods are provided by which Oryza sativa plants and seeds thereof may be modified to express a coding region of interest using a promoter sequence operatively linked to the coding region. The promoter sequence is an isolated Oryza sativa antiquitin (OsAnt1) promoter sequence including SEQ ID NO: 1. The coding region of interest may encode a nitrogen utilization protein, suitably alanine aminotransferase. Methods to develop Oryza sativa plants that have increased biomass and seed yield are also presented. Furthermore, Oryza sativa plants may be produced that maintain a desired yield while reducing the need for high levels of nitrogen application.

公开(公告)号：EP1427450A4

公开(公告)日：2005-09-14

申请号：EP02806826

申请日：2002-07-26

申请人： MIRUS CORP

发明人： LEWIS DAVID L

IPC分类号： C12N15/09 ,  A61K31/58 ,  A61K31/74 ,  A61K38/00 ,  A61K45/00 ,  A61K45/06 ,  A61K48/00 ,  A61P31/04 ,  A61P31/12 ,  A61P31/14 ,  C12N15/11 ,  C12N15/113 ,  C12N15/88

CPC分类号： C12N15/1137 ,  A61K31/58 ,  A61K31/74 ,  A61K38/00 ,  A61K48/00 ,  C12N15/111 ,  C12N15/88 ,  C12N2310/14 ,  C12N2320/32 ,  C12N2710/24111 ,  C12Y206/01002 ,  A61K2300/00

摘要： Described is a process for delivering an inhibitor directed against an expressible nucleic acid sequence in a mammal to inhibit RNA function. An RNA function inhibiting sequence that is specific to the expressible nucleic acid sequence in the mammal is made and inserted into a blood vessel in the mammal. The inhibitor is delivered to a cell wherein expression of the nucleic acid sequence is inhibited.

公开(公告)号：EP2753698A1

公开(公告)日：2014-07-16

申请号：EP12829500.3

申请日：2012-09-07

申请人： Bayer CropScience AG

发明人： GOOD, Allen ,  LOCK, Yee Ying ,  BEATTY, Perrin H.

IPC分类号： C12N15/82 ,  A01H5/00 ,  A01H5/10 ,  C12N15/113 ,  C12N15/54 ,  C12N5/10 ,  C12N5/04

CPC分类号： C12N15/8261 ,  C12N9/0008 ,  C12N9/1096 ,  C12Y102/01027 ,  C12Y206/01002 ,  Y02A40/146

摘要： A transgenic plant comprising a polynucleotide encoding a nitrogen utilization protein operably linked to a PBpr1 promoter is provided. The transgenic plant exhibits increased nitrogen use efficiency, increased biomass and/or increased seed yield. Seeds from such transgenic plants, genetic constructs to prepare such plants, methods of generating and growing transgenic plants are also provided.

公开(公告)号：EP1508617B1

公开(公告)日：2006-10-04

申请号：EP04077438.2

申请日：1999-04-23

申请人： SYSMEX CORPORATION

发明人： Baba, Toshiyuki, c/o Int. Reagents Corp. ,  Tabata, Hiromasa, c/o Int. Reagents Corp. ,  Nagamatsu, Katashi, c/o Int. Reagents Corp. ,  Watazu, Yoshifumi, c/o Int. Reagents Corp. ,  Aoki, Ryoji, c/o Int. Reagents Corp.

IPC分类号： C12N9/96 ,  C12N9/10

CPC分类号： C12Y206/01021 ,  C12N9/1096 ,  C12N9/96 ,  C12Y206/01001 ,  C12Y206/01002