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公开(公告)号：EP2252691B1
公开(公告)日：2013-03-27
申请号：EP09717549.1
申请日：2009-03-04
申请人： Firmenich S.A.
发明人： SCHALK, Michel
CPC分类号： C12N9/88 , C12P5/007 , C12P15/00 , C12Y402/03082
摘要： The present invention provides a method of producing α-santalene by contacting at least one polypeptide with farnesyl phyrophosphate (fpp). In particular, the method may be carried out in vitro or in vivo to produce α-santalene, a very useful compound in the fields of perfumery and flavoring. The present invention also provides the amino acid sequence of a polypeptide useful in the method of the invention. A nucleic acid encoding the polypeptide of the invention and an expression vector containing the nucleic acid represent part of the present invention. A non-human host organism and a cell transformed to be used in the method of producing α-santalene are also part of the present invention.
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公开(公告)号：EP2714901B1
公开(公告)日：2024-09-18
申请号：EP12728330.7
申请日：2012-05-31
CPC分类号： C12N15/8243 , C12Y402/00 , C12P5/007 , C12Y402/03053 , C12Y402/03054 , C12Y402/03082 , C12N9/88 , C12N15/8286 , Y02A40/146
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公开(公告)号：EP2449107B1
公开(公告)日：2015-04-08
申请号：EP10793414.3
申请日：2010-06-25
申请人： The University Of Western Australia , Forest Products Commission , University Of British Columbia
CPC分类号： C12P5/007 , C12N9/88 , C12P7/02 , C12P15/00 , C12Q1/527 , C12Q1/6895 , C12Y402/03081 , C12Y402/03082 , C12Y402/03083 , G01N33/573
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公开(公告)号：EP2714901A1
公开(公告)日：2014-04-09
申请号：EP12728330.7
申请日：2012-05-31
申请人： Keygene N.V.
CPC分类号： C12N15/8286 , A01H1/04 , C12N9/88 , C12N15/8239 , C12N15/8243 , C12P5/007 , C12Y402/00 , C12Y402/03053 , C12Y402/03054 , C12Y402/03082 , Y02A40/162
摘要： An isolated nucleic acid molecule encoding a 7-epizingiberene synthase, a chimeric gene comprising the nucleic acid molecule, vectors comprising the same, as well as isolated 7-epizingiberene synthase proteins themselves, are provided. In addition, transgenic plants and plant cells comprising a gene encoding a 7-epizingiberene synthase, optionally integrated in its genome, and methods for making such plants and cells, are provided. Especially Solanaceae plants and plant parts (seeds, fruit, leaves, etc.) with enhanced insect pest resistance are provided.
摘要翻译： 本发明提供了分离的核酸分子，其编码7-表位安全性合成酶，包含核酸分子的嵌合基因，包含该核酸分子的载体以及分离的7-表质酰胆碱合成酶本身。 此外，提供了转基因植物和植物细胞，其包含编码7-表位活性物质合成酶的基因，任选地整合在其基因组中，以及用于制备这种植物和细胞的方法。 提供了具有增强的害虫抗性的茄科植物和植物部分（种子，果实，叶子等）。
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公开(公告)号：EP2449107A4
公开(公告)日：2013-01-02
申请号：EP10793414
申请日：2010-06-25
CPC分类号： C12P5/007 , C12N9/88 , C12P7/02 , C12P15/00 , C12Q1/527 , C12Q1/6895 , C12Y402/03081 , C12Y402/03082 , C12Y402/03083 , G01N33/573
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6.发明公开MODIFIED SANTALENE SYNTHASE POLYPEPTIDES, ENCODING NUCLEIC ACID MOLECULES AND USES THEREOF 审中-公开改性三羟基磷灰石，意大利NUKLEINSÄUREMOLEKÜLEVERWENDUNGEN DAVON
公开(公告)号：EP3126492A2
公开(公告)日：2017-02-08
申请号：EP15717720.5
申请日：2015-03-30
申请人： Evolva, Inc.
IPC分类号： C12N9/88
CPC分类号： C12N9/88 , C12P5/007 , C12Y402/03082 , C12Y402/03083
摘要： Provided are modified santalene synthase polypeptides, nucleic acid molecules encoding the modified santalene synthase polypeptides, and methods of using the modified santalene synthase polypeptides. The modified santalene synthase polypeptides include those that catalyze production of increased levels of terpenes or altered profiles thereof or both.
摘要翻译： 提供了修饰的檀香烃合酶多肽，编码修饰的樟脑烯合酶多肽的核酸分子，以及使用修饰的ant烯合成酶多肽的方法。 修饰的樟脑烯合酶多肽包括催化萜烯增加或其变化的曲线或两者的生产的那些。
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公开(公告)号：EP2449107A1
公开(公告)日：2012-05-09
申请号：EP10793414.3
申请日：2010-06-25
申请人： The University Of Western Australia , Forest Products Commission , University Of British Columbia
CPC分类号： C12P5/007 , C12N9/88 , C12P7/02 , C12P15/00 , C12Q1/527 , C12Q1/6895 , C12Y402/03081 , C12Y402/03082 , C12Y402/03083 , G01N33/573
摘要： An isolated nucleic acid molecule that encodes a terpene synthase and is selected from among: a) a nucleic acid molecule comprising the sequence of nucleotides set forth in SEQ ID NO: 1, SEQ ID NO: 3 or SEQ ID NO: 5; b) a nucleic acid molecule that is a fragment of (a); c) a nucleic acid molecule comprising a sequence of nucleotides that is complementary to (a)-or (b); and d) a nucleic acid molecule that encodes a terpene synthase having at least or at least about or at least about 60%, 65%, 70%, 75%, 80%, 85%, 90%, 95%, 96%, 97%, 98%, 99% identity to any one of (a)-(c); wherein the nucleic acid molecule encodes a terpene synthase.
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公开(公告)号：EP2252691A1
公开(公告)日：2010-11-24
申请号：EP09717549.1
申请日：2009-03-04
申请人： Firmenich S.A.
发明人： SCHALK, Michel
CPC分类号： C12N9/88 , C12P5/007 , C12P15/00 , C12Y402/03082
摘要： The present invention provides a method of producing α-santalene by contacting at least one polypeptide with farnesyl phyrophosphate (fpp). In particular, the method may be carried out in vitro or in vivo to produce α-santalene, a very useful compound in the fields of perfumery and flavoring. The present invention also provides the amino acid sequence of a polypeptide useful in the method of the invention. A nucleic acid encoding the polypeptide of the invention and an expression vector containing the nucleic acid represent part of the present invention. A non-human host organism and a cell transformed to be used in the method of producing α-santalene are also part of the present invention.
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