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公开(公告)号：EP3382374A2
公开(公告)日：2018-10-03
申请号：EP18170833.0
申请日：2007-06-14
发明人： TEICH, Jay S.
CPC分类号： G01N33/5038 , B01L3/5025 , B01L3/50853 , B01L2300/046 , B01L2300/047 , B01L2300/0654 , B01L2300/0829 , B01L2400/0487 , C12M23/12 , C12M41/46 , G01N21/03 , G01N21/253 , G01N21/6428 , G01N21/6452 , G01N21/7703 , G01N35/00584 , G01N35/1002 , G01N2021/0325 , G01N2021/6434 , G01N2021/6484 , G01N2035/0091 , G01N2035/0094
摘要： Devices and methods that measure one or more properties of a living cell culture that is contained in liquid media within a vessel, and typically analyzes plural cell cultures contained in plural vessels such as the wells of a mutiwell microplate substantially in parallel. The devices incorporate a sensor that remains in equilibrium with, e.g., remains submerged within, the liquid cell media during the performance of a measurement and during addition of one or more cell affecting fluids such as solutions of potential drug compounds.
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公开(公告)号：EP3315594A1
公开(公告)日：2018-05-02
申请号：EP15896308.2
申请日：2015-06-24
申请人： Hitachi, Ltd.
发明人： YOKOI Takahide , SHIRAI Masataka
CPC分类号： C12Q1/02 , C12M1/34 , C40B40/06 , G01N1/00 , G01N1/2813 , G01N1/31 , G01N15/1475 , G01N35/00603 , G01N2015/1006 , G01N2035/0094 , G16B30/00 , G16B50/00
摘要： The present invention optically obtains characteristic values of a plurality of biological samples from a specimen; compares the characteristic values with examination information associated with the same specimen obtained in advance; and calculates an indicator to determine, based on a result of the comparison, whether a process is continued to genetic analysis of the biological samples or a re-preparation of samples from the same specimen is performed. By this method, it is possible to achieve more reliable biomarker detection by ensuring validity through appropriate selection of test samples while reducing cost, effort, and time for analysis in single cell analysis or analysis of a group of a small number of cells.
摘要翻译： 本发明从样本光学地获得多个生物样本的特征值; 将特征值与预先获得的与相同样本相关联的检查信息进行比较; 并基于比较结果计算指标以确定是否继续对生物样品进行遗传分析或者对来自同一样品的样品进行重新制备。 通过这种方法，通过适当选择测试样本确保有效性，同时降低单细胞分析或分析少数细胞群的成本，工作量和时间，可以实现更可靠的生物标志物检测。
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3.发明公开Sample inspection system and operating method for management server thereof 审中-公开其管理服务器的样本检测系统和操作方法
公开(公告)号：EP2237044A3
公开(公告)日：2018-04-04
申请号：EP10003364.6
申请日：2010-03-29
CPC分类号： G01N35/0092 , G01N35/0095 , G01N35/02 , G01N2035/00881 , G01N2035/0091 , G01N2035/0094 , G01N2035/0406 , G16H10/40 , Y02A90/22 , Y02A90/26
摘要： A management server (30) of a sample inspection system (1a) includes sample processing information (70) generated on the basis of inspection request data (60) accepted from a sample access system (50), facility data (80) having a processing time of the sample inspection line (20), a simulation execution portion (35) for executing simulation on the basis of the sample processing information (70) and the facility data (80) and a window generation portion (32) for generating a monitor window (100) to be outputted to a monitor device (40). The inspection request data (60) contains a priority (63), an order time (64), a required time (65) and inspection items (66) and the sample processing information (70) contains an inspection start time (P2) and an inspection estimate finish time (P3). The monitor window (100) has a work area (101) in which the samples represented by sample bars (Z) parallel to the abscissa are arranged in a vertical direction and a past record and a future schedule are allocated to this abscissa with the present time (P1) as the base. The sample bars (Z) display a simulation execution portion (35) for executing simulation on the basis of the inspection start time (P2), the inspection estimate finish time (P3) and a delay time (Z1). The management server (30) displays the simulation result of the simulation execution portion (85) on the monitor window (100).
摘要翻译： 样本检查系统（1a）的管理服务器（30）包括基于从样本访问系统（50）接受的检查请求数据（60）生成的样本处理信息（70），具有处理 （20）的时间;模拟执行部分（35），用于基于样本处理信息（70）和设施数据（80）执行模拟;窗口生成部分（32），用于生成监视器 窗口（100）输出到监视器装置（40）。 检查请求数据（60）包含优先顺序（63），顺序时间（64），所需时间（65）和检查项目（66），并且样本处理信息（70）包含检查开始时间（P2）和 检查估计完成时间（P3）。 监视器窗口（100）具有工作区域（101），其中由平行于横坐标的样本条（Z）表示的样本沿垂直方向排列，并且将过去记录和未来日程安排分配给该横坐标 时间（P1）为基数。 样本条（Z）基于检查开始时间（P2），检查估计完成时间（P3）和延迟时间（Z1）显示用于执行仿真的仿真执行部分（35）。 管理服务器（30）在监视窗口（100）上显示模拟执行部（85）的模拟结果。
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公开(公告)号：EP3276358A1
公开(公告)日：2018-01-31
申请号：EP17187105.6
申请日：2013-05-24
CPC分类号： G01N35/025 , G01N21/11 , G01N21/82 , G01N33/86 , G01N35/00584 , G01N35/00693 , G01N35/0092 , G01N35/1004 , G01N2021/115 , G01N2035/00425 , G01N2035/00673 , G01N2035/0094 , G01N2035/0097 , G01N2035/0437 , G01N2035/0453
摘要： An object of the present invention is to provide a high-throughput automatic analyzer that integrates a biochemical analysis section and a blood coagulation analysis section, the analyzer being capable of achieving a reduction in size, system cost, and lifecycle cost. The automatic analyzer includes: a reaction disk having a reaction cell arranged circumferentially thereon, the reaction cell mixing and reacting a sample and a reagent with each other, the reaction disk repeating rotation and stop; a first reagent dispensing mechanism that dispenses a reagent to the reaction cell; a photometer that irradiates a reaction solution in the reaction cell with light to thereby detect light; a reaction cell cleaning mechanism that cleans the reaction cell; a reaction vessel supply unit that supplies a disposable reaction vessel for mixing and reacting a sample and a reagent with each other; a second reagent dispensing mechanism with a reagent heating function that dispenses a reagent to the disposable reaction vessel; a blood coagulation time measuring section that irradiates a reaction solution in the disposable reaction vessel with light to thereby detect transmitted light or scattered light; and a sample dispensing mechanism that dispenses a sample to the reaction cell and the disposable reaction vessel.
摘要翻译： 本发明的目的在于提供一种将生物化学分析部和血液凝固分析部一体化的高生产率的自动分析装置，能够实现小型化，系统成本以及生命周期成本的降低。 该自动分析装置包括：具有沿周向排列的反应单元的反应盘，反应单元使样品和试剂相互混合并反应，反应盘反复旋转并停止; 第一试剂分配机构，其将试剂分配给反应池; 用光照射反应池中的反应溶液从而检测光的光度计; 清洁反应池的反应池清洁机构; 反应容器供应单元，其供应用于使样品和试剂彼此混合和反应的一次性反应容器; 具有试剂加热功能的第二试剂分配机构，其将试剂分配到一次性反应容器; 凝血时间测量部分，其用光照射所述一次性反应容器中的反应溶液，从而检测透射光或散射光; 以及样本分配机构，其将样本分配到反应池和一次性反应容器。
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公开(公告)号：EP2860528B1
公开(公告)日：2018-01-03
申请号：EP13804200.7
申请日：2013-05-24
CPC分类号： G01N35/025 , G01N21/11 , G01N21/82 , G01N33/86 , G01N35/00584 , G01N35/00693 , G01N35/0092 , G01N35/1004 , G01N2021/115 , G01N2035/00425 , G01N2035/00673 , G01N2035/0094 , G01N2035/0097 , G01N2035/0437 , G01N2035/0453
摘要： An object of the present invention is to provide a high-throughput automatic analyzer that integrates a biochemical analysis section and a blood coagulation analysis section, the analyzer being capable of achieving a reduction in size, system cost, and lifecycle cost. The automatic analyzer includes: a reaction disk having a reaction cell arranged circumferentially thereon, the reaction cell mixing and reacting a sample and a reagent with each other, the reaction disk repeating rotation and stop; a first reagent dispensing mechanism that dispenses a reagent to the reaction cell; a photometer that irradiates a reaction solution in the reaction cell with light to thereby detect light; a reaction cell cleaning mechanism that cleans the reaction cell; a reaction vessel supply unit that supplies a disposable reaction vessel for mixing and reacting a sample and a reagent with each other; a second reagent dispensing mechanism with a reagent heating function that dispenses a reagent to the disposable reaction vessel; a blood coagulation time measuring section that irradiates a reaction solution in the disposable reaction vessel with light to thereby detect transmitted light or scattered light; and a sample dispensing mechanism that dispenses a sample to the reaction cell and the disposable reaction vessel.
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6.发明公开FULL-AUTOMATIC BIOCHEMICAL ANALYZER, AND SAMPLING DEVICE AND SAMPLING METHOD THEREOF 审中-公开全自动生化分析仪，以及采样装置和采样方法
公开(公告)号：EP3214448A1
公开(公告)日：2017-09-06
申请号：EP14904731.8
申请日：2014-12-15
申请人： Leadway (HK) Limited
发明人： WANG, Bo , LUO, Cheng
CPC分类号： G01N35/10 , G01N35/00 , G01N35/025 , G01N2035/00534 , G01N2035/0094 , G06F19/00 , G06F19/34
摘要： The present invention provides an auto biochemical analyzer and a sampling device and a sampling method thereof. The auto biochemical analyzer comprises a frame (100), a horizontal motion system, a vertical motion system, a sampling component and a transfer guide track (101), wherein the horizontal motion system comprises a first stepping motor (116); the vertical motion system comprises a second stepping motor (103); the first stepping motor (116) and the second stepping motor (103) are fixedly installed on the frame (100) respectively; the sampling component comprises a sampling needle holder block (114) and a sampling needle (111); and the stepping motors (116, 103) are both fixed to the frame. The analyzer is smart in motion, low in cost and compact in structure, and has the functions of open sampling and closed puncturing as well as conveying a sample to a specific position.
摘要翻译： 本发明提供一种自动生化分析仪及其取样装置及其取样方法。 该自动生化分析仪包括框架（100），水平运动系统，垂直运动系统，采样部件和传送导轨（101），其中水平运动系统包括第一步进电机（116）; 垂直运动系统包括第二步进电机（103）; 第一步进电机116和第二步进电机103分别固定在机架100上， 采样部件包括采样针保持块（114）和采样针（111）; 和步进电机（116,103）都固定在框架上。 该分析仪运动灵活，成本低廉，结构紧凑，具有开放式取样和封闭式穿孔功能，并可将样品输送到特定位置。
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公开(公告)号：EP2943787A4
公开(公告)日：2016-08-24
申请号：EP14737525
申请日：2014-01-14
CPC分类号： G01N35/021 , G01N35/00663 , G01N35/00722 , G01N35/0092 , G01N35/0095 , G01N35/04 , G01N35/10 , G01N35/1002 , G01N2035/00326 , G01N2035/00673 , G01N2035/0091 , G01N2035/0094 , G01N2035/0467 , Y10T436/114165
摘要： An automation system for use with an in vitro diagnostics environment includes a track and a plurality of carriers configured to move along the track and hold one or more of a plurality of samples and one or more of a plurality of reagents having reagent types. The system also includes one or more testing stations, one or more local reagent storage areas located at or proximate to the one or more testing stations and one or more central reagent storage areas. The system further includes a control system configured to direct the one or more reagents from the one or more local reagent storage areas to the one or more testing stations based on received reagent information and direct the one or more reagents from the one or more central reagent storage areas to the one or more testing stations based on the received reagent information.
摘要翻译： 用于体外诊断环境的自动化系统包括轨道和多个载体，其构造成沿着轨道移动并保持多个样品中的一个或多个以及具有试剂类型的多种试剂中的一种或多种。 该系统还包括一个或多个测试站，位于或接近一个或多个测试站和一个或多个中心试剂储存区域的一个或多个局部试剂储存区域。 该系统还包括控制系统，其配置为基于接收到的试剂信息将一种或多种试剂从一个或多个局部试剂储存区域引导到一个或多个测试站，并将一种或多种试剂从一种或多种中间试剂 基于所接收的试剂信息将所述存储区域存储到所述一个或多个测试站。
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公开(公告)号：EP2860528A4
公开(公告)日：2016-03-09
申请号：EP13804200
申请日：2013-05-24
CPC分类号： G01N35/025 , G01N21/11 , G01N21/82 , G01N33/86 , G01N35/00584 , G01N35/00693 , G01N35/0092 , G01N35/1004 , G01N2021/115 , G01N2035/00425 , G01N2035/00673 , G01N2035/0094 , G01N2035/0097 , G01N2035/0437 , G01N2035/0453
摘要： An object of the present invention is to provide a high-throughput automatic analyzer that integrates a biochemical analysis section and a blood coagulation analysis section, the analyzer being capable of achieving a reduction in size, system cost, and lifecycle cost. The automatic analyzer includes: a reaction disk having a reaction cell arranged circumferentially thereon, the reaction cell mixing and reacting a sample and a reagent with each other, the reaction disk repeating rotation and stop; a first reagent dispensing mechanism that dispenses a reagent to the reaction cell; a photometer that irradiates a reaction solution in the reaction cell with light to thereby detect light; a reaction cell cleaning mechanism that cleans the reaction cell; a reaction vessel supply unit that supplies a disposable reaction vessel for mixing and reacting a sample and a reagent with each other; a second reagent dispensing mechanism with a reagent heating function that dispenses a reagent to the disposable reaction vessel; a blood coagulation time measuring section that irradiates a reaction solution in the disposable reaction vessel with light to thereby detect transmitted light or scattered light; and a sample dispensing mechanism that dispenses a sample to the reaction cell and the disposable reaction vessel.
摘要翻译： 本发明的目的是提供一种将生化分析部和血液凝固分析部进行集成的高通量自动分析装置，能够实现小型化，系统成本降低，生命周期成本的降低。 所述自动分析装置包括：反应盘，其具有周向配置的反应池，所述反应池使样品和试剂彼此混合并使反应盘反复旋转停止; 向反应池分配试剂的第一试剂分注机构; 光度计，其用光照射反应池中的反应溶液，从而检测光; 清洁反应池的反应池清洗机构; 反应容器供给单元，其供给用于使样品和试剂彼此混合和反应的一次性反应容器; 具有试剂加热功能的第二试剂分注机构，其向一次性反应容器分配试剂; 血液凝固时间测量部分，用光照射一次性反应容器中的反应溶液，从而检测透射光或散射光; 以及将样品分配到反应池和一次性反应容器的样品分配机构。
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公开(公告)号：EP2523003A8
公开(公告)日：2014-03-05
申请号：EP12171307.7
申请日：2003-06-20
发明人： Elliot, Stuart , McLellan, Andrew , Henderson, Chester , Dockrill, Mark , Harris, Simon , Riddell, Peter
CPC分类号： G01N35/1016 , B01L3/545 , B01L9/523 , G01N35/00029 , G01N35/0092 , G01N35/1002 , G01N2035/00079 , G01N2035/00138 , G01N2035/00168 , G01N2035/00752 , G01N2035/0094 , G01N2035/1025 , G01N2035/106 , G02B21/34 , G05B15/02 , Y10T436/112499
摘要： A biological reaction apparatus (10) for receiving at least one substrate having a sample located in a sample region, and a separate cover, such that a reaction chamber is formed between the cover and substrate over the sample region, wherein the apparatus (10) includes a locating means to locate the substrate; a cover locating means for locating and moving the cover with respect to the substrate; a fluid dispensing means for dispensing fluid into the reaction chamber; and a draining mechanism; wherein the draining mechanism includes wicking means.
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10.发明公开ARTICLE CONVEYING SYSTEM AND ANALYTE PROCESSING SYSTEM 有权ARTIKELFÖRDERUNGSSYSTEMUNDANALYTVERARBEITUNGSSYSTEM
公开(公告)号：EP2461165A4
公开(公告)日：2013-12-18
申请号：EP10804077
申请日：2010-07-20
CPC分类号： G01N35/00732 , G01N35/0092 , G01N35/026 , G01N2035/0094 , G01N2035/0472
摘要： An object of the present invention is to provide a sample processing system, wherein writing to each RFID is equalized to eliminate unevenness in the use of sample containers. The configuration of the present invention can be realized by controlling the numbers of times (write counts) data is written to RFIDs, and by skipping data writing according to frequencies in the use of sample containers. Setting use information (count) of each IC tag, and comparing the use information with an average value of the use of the IC tags, make it possible to limit the write counts, which enables the equalization of writing to the IC tags, thereby making it possible to uniform the use of the sample containers in the system.
摘要翻译： 本发明的目的是提供一种样品处理系统，其中对每个RFID进行写入是均衡的，以消除使用样品容器的不均匀性。 本发明的结构可以通过控制将数据写入RFID的次数（写入计数）和通过使用样品容器中的频率跳过数据写入来实现。 设置每个IC标签的使用信息（计数），并将使用信息与IC标签的使用的平均值进行比较，使得可以限制写入计数，这使得能够对IC标签进行写入的均衡，由此 可以使系统中样品容器的使用均匀。
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