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公开(公告)号:EP3940382B1
公开(公告)日:2024-07-03
申请号:EP21181440.5
申请日:2019-03-22
IPC分类号: G01N33/569 , G01N33/68
CPC分类号: G01N33/56977 , G01N33/6818 , G01N33/6848 , G01N2333/7053920130101
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公开(公告)号:EP4423503A1
公开(公告)日:2024-09-04
申请号:EP22813073.8
申请日:2022-10-30
申请人: Immunoracle Inc.
发明人: SHI, Yujiang Geno
IPC分类号: G01N33/569 , G01N33/574
CPC分类号: G01N33/57484 , G01N33/56972 , A61P35/00 , G01N2333/7053920130101
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公开(公告)号:EP4407622A2
公开(公告)日:2024-07-31
申请号:EP24167053.8
申请日:2016-07-14
IPC分类号: G16B20/20
CPC分类号: G16H10/40 , G01N33/6878 , G01N33/57484 , C12Q1/6886 , G01N33/574 , G01N2333/7053920130101 , C12Q2600/15620130101 , C12Q2600/13620130101 , G16B20/00 , G16B35/20 , G16B20/20 , G16B20/40
摘要: Cancer immunology provides promising new avenues for cancer treatment but validation of potential neoantigens to target is costly and expensive. Analysis of MHC binding affinity, antigen processing, similarity to known antigens, predicted expression levels (as mRNA or proteins), self- similarity, and mutant allele frequency, provides screening method to identify and prioritize candidate neoantigens using sequencing data. Methods of the invention thereby save time and money by identifying the priority candidate neoantigens for further experimental validation.
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公开(公告)号:EP4363858A1
公开(公告)日:2024-05-08
申请号:EP22735441.2
申请日:2022-06-28
发明人: SCHRÄDER, Christoph , SCHUSTER, Heiko , FREUDENMANN, Lena , GOLDFINGER, Valentina , KOWALEWSKI, Daniel , YOUSEF, Sara , MANZ, Timo , MIJOSEK, Vedrana , RÖMER, Michael , WEINSCHENK, Toni
IPC分类号: G01N33/68
CPC分类号: G01N33/6848 , G01N2333/7053920130101 , G01N2496/0020130101 , Y02A50/30 , A61K39/4611 , A61K39/464489 , A61K39/4632 , C12N5/0636
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公开(公告)号:EP3323070B1
公开(公告)日:2024-05-08
申请号:EP16825179.1
申请日:2016-07-14
IPC分类号: C12Q1/6886 , G16H10/40 , G16B20/00 , G16B20/40 , G16B35/20 , G01N33/569 , G01N33/68 , G01N33/574 , G01N35/00 , G16B20/20
CPC分类号: G16H10/40 , G01N33/6878 , G01N33/57484 , C12Q1/6886 , G01N33/574 , G01N2333/7053920130101 , C12Q2600/15620130101 , C12Q2600/13620130101 , G16B20/00 , G16B35/20 , G16B20/20 , G16B20/40
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公开(公告)号:EP4433087A1
公开(公告)日:2024-09-25
申请号:EP22896753.5
申请日:2022-11-18
发明人: JOSHI, Ila , ROYCHOWDHURY, Debasish
IPC分类号: A61K39/395 , A61K38/19 , G01N33/569 , C07K16/24
CPC分类号: G01N33/57492 , G01N2333/7053920130101 , G01N2800/5220130101 , A61K38/193 , A61P35/00
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公开(公告)号:EP4396586A1
公开(公告)日:2024-07-10
申请号:EP22777527.7
申请日:2022-08-29
申请人: Genentech, Inc.
IPC分类号: G01N33/68 , C07K14/74 , C07K7/06 , G01N33/569
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