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1.发明公开METHODS OF NORMALIZING MEASURED DRUG CONCENTRATIONS AND TESTING FOR POTENTIAL NON-COMPLIANCE WITH A DRUG TREATMENT REGIMEN 审中-公开方法进行归一化在具有药物的治疗方案可能未遵守的主动与试验实测浓度
公开(公告)号：EP2972318A4
公开(公告)日：2016-10-05
申请号：EP14764485
申请日：2014-03-17
发明人： LEIDER HARRY
IPC分类号： G01N33/493 , G01N33/94
CPC分类号： G01N33/9486 , G01N33/70 , G01N33/9466 , G01N33/948
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2.发明公开
公开(公告)号：EP2888286A4
公开(公告)日：2016-03-23
申请号：EP13830990
申请日：2013-08-20
发明人： HRYHORENKO ERIC , SANKARAN BANUMATHI , DECORY THOMAS R , TUBBS THERESA , COLT LINDA , REMMERIE BART M , SALTER RHYS , DONAHUE MATTHEW GARRETT , GONG YONG
IPC分类号： C07K16/44 , A61K31/551 , C07K14/00 , G01N33/94
CPC分类号： C07K16/44 , G01N33/94 , G01N33/9466
摘要： Disclosed is an antibody which binds to quetiapine, which can be used to detect quetiapine in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of quetiapine, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.
摘要翻译： 公开了结合喹硫平的抗体，其可用于检测样品中的喹硫平，例如在竞争性免疫测定法中。 该抗体可用于侧流测定装置，用于在喹诺酮治疗中进行点检测，包括在单个侧流测定装置中多次检测阿立哌唑，奥氮平，喹硫平和利培酮。
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公开(公告)号：EP2888592A2
公开(公告)日：2015-07-01
申请号：EP13831507.2
申请日：2013-08-20
发明人： HRYHORENKO, Eric , SANKARAN, Banumathi , DECORY, Thomas R. , TUBBS, Theresa , COLT, Linda , REMMERIE, Bart M. , SALTER, Rhys , DONAHUE, Matthew Garrett , GONG, Yong
IPC分类号： G01N33/53
CPC分类号： G01N33/9466 , C07K16/44 , C07K2317/56 , C07K2317/565 , G01N33/94
摘要： Disclosed is an antibody which binds to quetiapine, which can be used to detect quetiapine in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of quetiapine, including muitiplex detection of aripiprazole, quetiapine, olanzapine, and risperidone in a single lateral flow assay device.
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公开(公告)号：EP1884568A1
公开(公告)日：2008-02-06
申请号：EP06745969.3
申请日：2006-05-01
发明人： OHARA, Osamu KAZUSA DNA RESEARCH INST. FOUNDATION , NAGASE, T. KAZUSA DNA RESEARCH INST. FOUNDATION , OHISHI, M. KAZUSA DNA RESEARCH INST. FOUNDATION , OKAJIMA, Daisuke Daiichi Sankyo Co Ltd , YOKOTA, Hiroshi Daiichi Sankyo Co Ltd
IPC分类号： C12N15/09 , C07K14/705 , C12N1/15 , C12N1/19 , C12N1/21 , C12N5/10 , C12P21/02 , C12Q1/02 , G01N33/15 , G01N33/50 , A61K45/00 , A61P25/24 , C07K16/28
CPC分类号： C07K14/705 , A61K38/00 , G01N33/6896 , G01N33/9466 , G01N2333/726 , G01N2500/00 , G01N2800/304
摘要： The present invention intended to find out a gene encoding a protein having functions equivalent to those of G-protein-coupled receptor (GPCR) and the protein, and to provide a method for identifying a compound that regulates functions and/or expression of the protein and a useful means for preventing and/or treating diseases relating to the gene and the protein, and has provided a DNA comprising nucleotide sequence as set forth in SEQ ID NO: 1 or complementary strand thereof, equivalents of the DNA, a protein encoded by the DNA, a vector containing the DNA, a transformant containing the vector, an antibody against the protein, a method for identifying a compound that regulates functions and/or expression of the protein using aforementioned members, an agent and a method for improving depression state, a pharmaceutical composition, and a reagent kit.
摘要翻译： 本发明旨在发现编码具有与G蛋白偶联受体（GPCR）和蛋白质相同功能的蛋白质的基因，并提供鉴定调节蛋白质功能和/或表达的化合物的方法 以及用于预防和/或治疗与基因和蛋白质有关的疾病的有用手段，并提供了包含如SEQ ID NO：1所示的核苷酸序列或其互补链的DNA，该DNA的等价物，由 该DNA，含有该DNA的载体，含有该载体的转化体，针对该蛋白质的抗体，使用上述成员鉴定调节该蛋白质的功能和/或表达的化合物的方法，改善抑郁状态的药剂和方法 ，药物组合物和试剂盒。
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公开(公告)号：EP1730525A1
公开(公告)日：2006-12-13
申请号：EP05725315.5
申请日：2005-03-10
申请人： Seradyn Inc.
发明人： ROBERTS, Mark , ARABSHAHI, Lili , BOYD, Jared , DENNIS, Christopher, T. , MARBACH, Peter , AARON, George , HWANG, Deng , SHVETS, Alexei, Boris
IPC分类号： G01N33/53 , G01N33/531 , G01N33/532 , G01N33/533 , A61K39/385 , C07K17/00 , C07D267/22
CPC分类号： G01N33/9466 , C07K16/44 , G01N33/9493 , Y10S435/81 , Y10S435/975 , Y10S436/815 , Y10S530/807 , Y10T436/13
摘要： Immunoassays for the detection of everolimus are provided. Compounds for producing antibodies for everolimus, as well as antibodies produced therefrom, are also provided.
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公开(公告)号：EP0226730B1
公开(公告)日：1994-03-02
申请号：EP86113654.7
申请日：1986-10-03
申请人： ABBOTT LABORATORIES
IPC分类号： C07D223/28 , C07C211/60 , C07D405/12 , C07D311/82 , G01N33/94 , G01N21/64
CPC分类号： C07D405/12 , C07D223/08 , G01N33/9466
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7.发明授权Serum pretreatment for tricyclic antidepressant drug assays and kit therefor 失效用于三线抗体药物测定及其套件的血清预处理
公开(公告)号：EP0177344B1
公开(公告)日：1992-04-08
申请号：EP85307045.6
申请日：1985-10-02
申请人： SYNTEX (U.S.A.) INC.
IPC分类号： G01N33/44
CPC分类号： G01N33/9466 , Y10T436/141111
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8.发明公开Compounds and assay for tricyclic antidepressants 失效Verbindungen und Immunoassayfürtricyclische Antidepressiva。
公开(公告)号：EP0226730A2
公开(公告)日：1987-07-01
申请号：EP86113654.7
申请日：1986-10-03
申请人： ABBOTT LABORATORIES
IPC分类号： C07D223/28 , C07C211/60 , C07D405/12 , C07D311/82 , G01N33/94 , G01N21/64
CPC分类号： C07D405/12 , C07D223/08 , G01N33/9466
摘要： Reagents, compounds useful for producing the reagents and fluorescence polarization immunoassay utilizing the reagents, for determining tricyclic antidepressants in biological fluids, are disclosed.
摘要翻译： 公开了试剂，用于制备试剂的化合物和利用试剂的荧光偏振免疫测定法，用于测定生物流体中的三环抗抑郁药。
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公开(公告)号：EP2650686B1
公开(公告)日：2015-07-22
申请号：EP13163144.2
申请日：2013-04-10
IPC分类号： G01N33/94 , C07C217/64
CPC分类号： G01N33/9466 , C07C217/64
摘要： The invention describes antibodies that bind venlafaxine and O-desmethylvenlafaxine. The antibodies are derived from novel haptens and immunogens and are used in methods and kits to detect and quantify venlafaxine and O-desmethylvenlafaxine. The invention also describes novel detecting agents which can be used in the methods and kits of the invention.
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公开(公告)号：EP2888286A1
公开(公告)日：2015-07-01
申请号：EP13830990.1
申请日：2013-08-20
发明人： HRYHORENKO, Eric , SANKARAN, Banumathi , DECORY, Thomas R. , TUBBS, Theresa , COLT, Linda , REMMERIE, Bart M. , SALTER, Rhys , DONAHUE, Matthew Garrett , GONG, Yong
IPC分类号： C07K16/44 , C07K14/00 , A61K31/551
CPC分类号： C07K16/44 , G01N33/94 , G01N33/9466
摘要： Disclosed is an antibody which binds to quetiapine, which can be used to detect quetiapine in a sample such as in a competitive immunoassay method. The antibody can be used in a lateral flow assay device for point-of-care detection of quetiapine, including multiplex detection of aripiprazole, olanzapine, quetiapine, and risperidone in a single lateral flow assay device.
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