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231 条记录 (耗时 0.015 秒)

    Signalling compounds for use in methods of detecting hydrogen peroxide
    1.
    发明公开
    Signalling compounds for use in methods of detecting hydrogen peroxide 有权
    信号信号（Zen Verwendung bei Verfahren zur Erkennung von Wasserstoffperoxid

    公开(公告)号：EP2305690A1

    公开(公告)日：2011-04-06

    申请号：EP10183552.8

    申请日：2004-02-17

    申请人： LUMIGEN, INC.

    发明人： Akhavan-Tafti, Hashem ,  Eickholt, Robert A ,  Lauwers, Kenneth S ,  Handley, Richard S

    IPC分类号： C07F5/02 ,  G01N33/533

    CPC分类号： C07F5/025 ,  G01N33/533 ,  Y10S436/904 ,  Y10T436/141111 ,  Y10T436/142222 ,  Y10T436/206664

    摘要： Methods and compound useful for detecting a source of hydrogen peroxide are disclosed wherein a signalling compound of formula

    is reacted with peroxide. A detectable product compound of the formula Sig - OH or Sig-O is produced and detected by measuring color, absorbance, fluorescence, chemiluminescence or bioluminescence. The signalling compound itself does not possess the detectable property or does so only to a very weak degree. The methods can be used as a detectable signal in assays for peroxide or peroxide-producing enzymes and in assays employing enzyme-labeled specific binding pairs. The signaling compound has the formula:

    wherein B is a boron atom, R 5 and R 6 are independently selected from hydrogen and lower alkyl groups and can be joined together as a straight or branched alkylene chain forming a five or six-membered ring or an arylene ring, and R 13 is independently selected from cyano, imine, carbonyl, thiazole, carbonyl-substitute thiazole and benzothiazole groups or a group

    wherein Z is C-C double or triple bond or aromatic ring and n is 1 or 2.

    摘要翻译： 公开了用于检测过氧化氢源的方法和化合物，其中式的信号化合物与过氧化物反应。 通过测量颜色，吸光度，荧光，化学发光或生物发光产生和检测式Sig-OH​​或Sig-O的可检测产物化合物。 信号化合物本身不具有可检测的性质，或仅在很弱的程度上这样做。 该方法可用作过氧化物或产生过氧化物酶的测定中的可检测信号，以及使用酶标记的特异性结合对的测定中。 信号化合物具有下式：其中B是硼原子，R 5和R 6独立地选自氢和低级烷基，并且可以连接在一起作为形成五或六元环的直链或支链亚烷基链或 亚芳基环，R 13独立地选自氰基，亚胺，羰基，噻唑，羰基 - 取代的噻唑和苯并噻唑基团或其中Z为CC双键或三键或芳环且n为1或2的基团。

    Chemiluminescence method using a 1,2-dioxetane derivative, and composition for chemiluminescence comprising it
    2.
    发明公开
    Chemiluminescence method using a 1,2-dioxetane derivative, and composition for chemiluminescence comprising it 有权
    通过化学发光的1,2-二氧杂环丁烷衍生物的方法，和该含组合物的化学发光

    公开(公告)号：EP1510822A3

    公开(公告)日：2008-05-21

    申请号：EP04020501.5

    申请日：2004-08-27

    申请人： TOSOH CORPORATION

    发明人： Kitaoka, Kenji ,  Yamada, Masashi ,  Kawaguchi, Seiji

    IPC分类号： G01N33/58 ,  G01N33/533 ,  G01N21/76 ,  C09K11/07

    CPC分类号： G01N33/582 ,  C09K11/07 ,  C09K2211/1007 ,  Y10S435/968 ,  Y10S436/904

    摘要： A chemiluminescence method characterized in that a 1,2-dioxetane derivative of the formula 1:

    wherein each of R 1 , R 2 , R 3 , R 4 and R 5 which are independent of one another, is a hydrogen atom, an alkyl group or an aryl group, or each pair of R 2 and R 3 , and R 4 and R 5 , which are independent of each other, may form together a cyclic alkyl group, R 6 is a hydroxyl group, an alkoxyl group, an aralkyloxy group, a group represented by -OSi(R 8 R 9 R 10 ) (provided that each of R 8 , R 9 and R 10 which are independent of one another, is an alkyl group or an aryl group), a phosphate group or a group represented by S(C=O)R 11 (provided that R 11 is an alkyl group or an aryl group), and R 7 is a hydrogen atom, a halogen atom, an alkyl group or an alkoxyl group, is let generate chemiluminescence by means of an activator (selected from the group consisting of a base, an acid, a salt, a fluorine compound, an enzyme, a catalyst and an amine compound), a cationic surfactant and a fluorescent material.

    SYSTEMS AND METHODS FOR QUANTIFYING PHOTOREACTIONS IN LIGHT ACTIVATED MATERIALS
    6.
    发明公开
    SYSTEMS AND METHODS FOR QUANTIFYING PHOTOREACTIONS IN LIGHT ACTIVATED MATERIALS 失效
    VICHELKTIVIERTEN SUBSTANZEN的VORRICHTUNGEN UND VERFAHREN ZUM QUANTIFIZIEREN VON PHOTOREATING

    公开(公告)号：EP0900371A4

    公开(公告)日：2000-12-13

    申请号：EP97950881

    申请日：1997-12-09

    申请人： BAXTER INT

    发明人： CHAPMAN JOHN ,  MATHIAS JEAN-MARIE

    IPC分类号： A61M1/36 ,  A61K31/00 ,  A61K31/54 ,  A61K31/5415 ,  A61K41/00 ,  A61P31/00 ,  A61P31/12 ,  G01N21/75 ,  G01N21/78 ,  A61L2/00

    CPC分类号： A61K41/0019 ,  Y10S436/904 ,  Y10S436/905

    摘要： Systems and methods are disclosed for treating biological fluids carrying contaminants by photoactivating materials mixed with the fluids. The system (10) comprises a vessel (12) having a transparent region and containing a solution (14) comprising a photoactive material which undergoes reduction oxidation in response to exposure to a prescribed light energy, and a reducing agent mixed with the photoactive material.

    摘要翻译： 公开了用于通过与流体混合的光活化材料处理携带污染物的生物流体的系统和方法。 系统（10）包括具有透明区域并容纳包含光敏材料的溶液（14）的容器（12），所述光敏材料响应于暴露于规定光能而进行还原氧化，还包括与光敏材料混合的还原剂。

    METHOD FOR DETERMINING DISSOLVED OXYGEN IN WATER
    7.
    发明公开
    METHOD FOR DETERMINING DISSOLVED OXYGEN IN WATER 失效
    法测定水中溶解氧

    公开(公告)号：EP0826143A4

    公开(公告)日：2000-12-06

    申请号：EP95920438

    申请日：1995-05-15

    申请人： AQUARIUM PHARMA

    发明人： ELSON JESSE ,  YOSHPA MICHAEL

    IPC分类号： G01N21/78 ,  G01N31/22 ,  G01N33/18 ,  G01N21/00 ,  G01N21/75 ,  G01N33/00

    CPC分类号： G01N31/225 ,  G01N21/78 ,  G01N33/1806 ,  Y10S436/904 ,  Y10T436/209163

    摘要： The invention relates to a method for determining the concentration of dissolved oxygen in a liquid water sample comprising the steps: (a) providing a liquid water sample of predetermined volume, the oxygen content of which is to be determined; (b) mixing additives with the liquid water sample to form a mixture, the additives comprising an oxidizable metal salt comprising a metal cation and an anion selected from an inorganic anion or an organic anion which, with the cation, results in a water soluble oxidizable metal salt, at least one water soluble alkali metal compound selected from an alkali metal oxide, or an alkali metal hydroxide or a salt of an alkali metal and a weak acid; and at least one oxidation-reduction indicator capable of a color change upon oxidation of the oxidizable metal salt during contact with dissolved oxygen in the liquid sample to a color indicative of the concentration of dissolved oxygen in the liquid sample; (c) preventing any substantial contact of the mixture with atmospheric oxygen; and (d) determining the concentration of dissolved oxygen in the liquid sample by comparing the color of the mixture to a predetermined color indicative of the concentration of dissolved oxygen in the water sample.

    Assay for the detection of creatinine
    8.
    发明公开
    Assay for the detection of creatinine 审中-公开
    测定zum Nachweis von Creatinin

    公开(公告)号：EP1022566A2

    公开(公告)日：2000-07-26

    申请号：EP00100216.1

    申请日：2000-01-14

    申请人： Bayer Corporation

    发明人： Messenger, Koleen K. ,  Pugia, Michael J.

    IPC分类号： G01N33/70

    CPC分类号： G01N33/70 ,  Y10S436/904 ,  Y10T436/147777 ,  Y10T436/16

    摘要： Disclosed is an improved method for the detection of creatinine in a fluid test sample by contacting the test sample with cupric ions, a hydroperoxide, citrate and an oxidizable dye which gives a colored response in the presence of oxygen free radicals and a pseudoperoxide. The improvement involves stabilizing the reagent formulation by the addition thereto of an ionizable phosphate containing compound such as phytic acid.

    摘要翻译： 公开了一种用于通过使测试样品与铜离子，氢过氧化物，柠檬酸盐和可氧化染料接触来检测流体测试样品中肌酸酐的改进方法，其在氧自由基和假过氧化物存在下产生着色反应。 该改进涉及通过加入其中的可电离的含磷酸化合物如植酸来稳定试剂制剂。