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1.发明公开DRY POWDER FORMULATION COMPRISING A CORTICOSTEROID AND A BETA-ADRENERGIC FOR ADMINISTRATION BY INHALATION 审中-公开干粉制剂与皮质类固醇和β肾上腺素通过吸入给药
公开(公告)号：EP3020394A1
公开(公告)日：2016-05-18
申请号：EP15202117.6
申请日：2013-01-23
Applicant: CHIESI FARMACEUTICI S.p.A.
Inventor： MONARI, Elisa , CANTARELLI, Anna Maria , COCCONI, Daniela , PASQUALI, Irene
IPC: A61K9/14 , A61K31/167 , A61K31/573 , A61P11/00 , A61P11/06
CPC classification number: A61K31/573 , A61K9/0075 , A61K9/14 , A61K9/145 , A61K31/167 , A61K31/20 , A61K47/26 , A61M15/003 , A61M15/009 , A61M2202/064 , A61P11/00 , A61P11/06 , Y10S514/826 , A61K2300/00
Abstract: The invention relates to a dry powder formulation comprising a corticosteroid and a beta 2 -adrenergic drug in combination, its process of preparation, and therapeutic uses thereof.
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公开(公告)号：EP2444092B1
公开(公告)日：2015-09-02
申请号：EP11191434.7
申请日：2009-05-28
Applicant: ReveraGen BioPharma, Inc.
Inventor： Mccall, John, M , Hoffman, Eric , Kanneboyina, Nagaraju
IPC: A61K31/575 , A61P21/00 , A61P19/02 , A61P11/06
CPC classification number: A61K31/573 , A61K31/57 , A61K31/575 , C07J5/0038 , C07J5/0053 , C07J5/0076 , Y02A50/479 , Y10S514/825 , Y10S514/826 , Y10S514/903
Abstract: The present invention relates to compounds and methods which may be useful as treatments of neuromuscular diseases such as muscular dystrophy, and as inhibitors of NF-ºB for the treatment or prevention of muscular wasting disease, including muscular dystrophy.
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3.发明公开DRY POWDER FORMULATION COMPRISING A CORTICOSTEROID AND A BETA-ADRENERGIC FOR ADMINISTRATION BY INHALATION 有权EINEM BETA-ADRENERGIKUM ZUR VERABREICHUNG MITTELS INHALATION的TROCKENPULVERFORMULIERUNG MIT EINEM CORTICOSTEROID
公开(公告)号：EP2806855A1
公开(公告)日：2014-12-03
申请号：EP13704372.5
申请日：2013-01-23
Applicant: Chiesi Farmaceutici S.p.A.
Inventor： MONARI, Elisa , CANTARELLI, Anna Maria , COCCONI, Daniela , PASQUALI, Irene
IPC: A61K9/14 , A61K31/167 , A61K31/57 , A61P11/00 , A61P11/06
CPC classification number: A61K31/573 , A61K9/0075 , A61K9/14 , A61K9/145 , A61K31/167 , A61K31/20 , A61K47/26 , A61M15/003 , A61M15/009 , A61M2202/064 , A61P11/00 , A61P11/06 , Y10S514/826 , A61K2300/00
Abstract: The invention relates to a dry powder formulation comprising a corticosteroid and a beta 2 -adrenergic drug in combination, its process of preparation, and therapeutic uses thereof.
Abstract translation: 本发明涉及一种组合包含皮质类固醇和β2-肾上腺素能药物的干粉制剂，其制备方法及其治疗用途。
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4.发明公开Non-hormonal steroid modulators of nf-kb for treatment of disease 有权Nichthormonale steroide Modulatoren von NF-KB zur Krankheitsbehandlung
公开(公告)号：EP2444092A1
公开(公告)日：2012-04-25
申请号：EP11191434.7
申请日：2009-05-28
Applicant: Validus Biopharma, Inc.
Inventor： Mccall, John, M , Hoffman, Eric , Kanneboyina, Nagaraju
IPC: A61K31/575 , A61P21/00 , A61P19/02 , A61P11/06
CPC classification number: A61K31/573 , A61K31/57 , A61K31/575 , C07J5/0038 , C07J5/0053 , C07J5/0076 , Y02A50/479 , Y10S514/825 , Y10S514/826 , Y10S514/903
Abstract: The present invention relates to compounds and methods which may be useful as treatments of neuromuscular diseases such as muscular dystrophy, and as inhibitors of NF-κB for the treatment or prevention of muscular wasting disease, including muscular dystrophy.
Abstract translation: 本发明涉及可用作治疗神经肌肉疾病如肌营养不良的化合物和方法，以及作为NF-ºB抑制剂用于治疗或预防肌肉萎缩性疾病，包括肌营养不良症的化合物和方法。
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5.发明公开
公开(公告)号：EP2269648A3
公开(公告)日：2012-04-18
申请号：EP10183425.7
申请日：2000-05-03
Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
Inventor： Bozung, Karlheinz , Walland, Alexander , Reichl, Richard , Pairet, Michel
IPC: A61K45/06 , A61K31/46 , A61K31/40 , A61K31/138 , A61K31/167 , A61P11/00 , A61P11/06 , A61K31/137 , A61K31/277 , A61K31/4184 , A61K31/428 , A61K31/536
CPC classification number: A61K31/138 , A61K9/0075 , A61K9/0078 , A61K31/137 , A61K31/167 , A61K31/277 , A61K31/40 , A61K31/4184 , A61K31/428 , A61K31/439 , A61K31/46 , A61K31/536 , A61K45/06 , Y10S514/826 , A61K2300/00
Abstract: Die vorliegende Erfindung betrifft neurtige Arzneimittelkompositionen auf der Basis von anticholinergisch langwirksamen Verbindungen und langwirksamen β-Mimetika, Verfahren zu deren Herstellung und deren Verwendung bei der Therapie von Atemwegserkrankungen.
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Patent Agency Ranking6.发明公开
公开(公告)号：EP2269647A2
公开(公告)日：2011-01-05
申请号：EP10183369.7
申请日：2000-05-03
Applicant: Boehringer Ingelheim Pharma GmbH & Co. KG
Inventor： Bozung, Karlheinz , Walland, Alexander , Reichl, Richard , Pairet, Michel
IPC: A61K45/06 , A61K31/46 , A61K31/40 , A61K31/138 , A61K31/167 , A61P11/00 , A61P11/06 , A61K31/137 , A61K31/277 , A61K31/4184 , A61K31/428 , A61K31/536
CPC classification number: A61K31/138 , A61K9/0075 , A61K9/0078 , A61K31/137 , A61K31/167 , A61K31/277 , A61K31/40 , A61K31/4184 , A61K31/428 , A61K31/439 , A61K31/46 , A61K31/536 , A61K45/06 , Y10S514/826 , A61K2300/00
Abstract: Die vorliegende Erfindung betrifft neurtige Arzneimittelkompositionen auf der Basis von anticholinergisch langwirksamen Verbindungen und langwirksamen β-Mimetika, Verfahren zu deren Herstellung und deren Verwendung bei der Therapie von Atemwegserkrankungen.
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7.发明公开Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und B-Mimetika 审中-公开基于抗胆碱能化合物和有效B-模拟物新药物组合物
公开(公告)号：EP1570861A3
公开(公告)日：2010-12-29
申请号：EP05008960.6
申请日：2000-05-03
Applicant: Boehringer Ingelheim Pharma GmbH & Co.KG
Inventor： Bozung, Karlheinz , Jung, Helga , Pairet, Michel , Reichl, Richard , Walland, Alexander
IPC: A61K45/06 , A61K31/46 , A61K31/40 , A61K31/138 , A61K31/167
CPC classification number: A61K31/138 , A61K9/0075 , A61K9/0078 , A61K31/137 , A61K31/167 , A61K31/277 , A61K31/40 , A61K31/4184 , A61K31/428 , A61K31/439 , A61K31/46 , A61K31/536 , A61K45/06 , Y10S514/826 , A61K2300/00
Abstract: Die vorliegende Erfindung betrifft neurtige Arzneimittelkompositionen auf der Basis von anticholinergisch langwirksamen Verbindungen und langwirksamen β-Mimetika, Verfahren zu deren Herstellung und deren Verwendung bei der Therapie von Atemwegserkrankungen.
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公开(公告)号：EP1551455A4
公开(公告)日：2009-06-24
申请号：EP03752262
申请日：2003-09-10
Applicant: NAT JEWISH MED & RES CENTER
Inventor： WHITE CARL W
IPC: A61K9/00 , A61K9/14 , A61K31/385 , A61K38/05 , A61K38/06 , A61K38/44 , A61L9/04 , A61K45/00 , A61K38/00 , C07K14/00
CPC classification number: A61K38/44 , A61K9/0053 , A61K31/385 , A61K31/7084 , C12N9/0051 , C12Y108/01009 , C12Y108/0401 , Y10S514/824 , Y10S514/826 , Y10S514/886 , A61K2300/00
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公开(公告)号：EP1055426B1
公开(公告)日：2008-11-12
申请号：EP99954401.8
申请日：1999-11-05
Applicant: TAIHO PHARMACEUTICAL COMPANY, LIMITED
Inventor： YAMAUCHI, Tamio , UEDA, Tomohiro
IPC: A61K31/167 , A61P13/08 , A61P13/10 , A61P35/00
CPC classification number: A61K45/06 , A61K31/167 , Y10S514/826 , Y10S514/869 , Y10S514/968 , A61K2300/00
Abstract: Remedies for dysuria and lower urinary tract diseases, containing as the active ingredient [2-[4-(3-ethoxy-2-hydroxypropoxy)phenylcarbamoyl]-ethyl]dimethylsulfonium salts of organic acids. These remedies enable the treatment of lower urinary tract diseases causative of dysuria, e.g., interstitial cystitis and prostatitis which have not yet been elucidated in the cause and have been believed to be intractable.
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公开(公告)号：EP1924264A1
公开(公告)日：2008-05-28
申请号：EP06778331.6
申请日：2006-08-23
Applicant: F.HOFFMANN-LA ROCHE AG
Inventor： BROKA, Chris Allen , CARTER, David Scott , DILLON, Michael Patrick , FORD, Anthony P.D.W. , HAWLEY, Ronald Charles , JAHANGIR, Alam , MOORE, Amy Geraldine , PARISH, Daniel Warren
IPC: A61K31/505 , A61K31/506 , A61P11/00 , A61P11/06 , A61P1/00
CPC classification number: A61K31/506 , A61K31/505 , A61K31/513 , A61K31/538 , Y10S514/826
Abstract: Methods for treating respiratory and gastrointestinal diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist, the methods comprising administering to a subject in need thereof an effective amount of a compound of formula (I) or a pharmaceutically acceptable salt thereof, wherein D, X, Y, R1, R2, R3, R4, R5, R6, R7 and R8 are as defined herein.
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