摘要:
The disclosure provides methods of use of certain compounds that are useful for treating certain symptoms of endocrine disturbances, and in particular those associated with hot flashes.
摘要:
Compounds having the formula: and fuel soluble salts thereof; wherein R 1 is nitro or -(CH 2 ) x -NR 4 R 5 , wherein R 4 and R 5 are independently hydrogen or lower alkyl and x is 0 or 1; R 2 is hydrogen, hydroxy, nitro, or -NR 6 R 7 wherein R 6 and R 7 are independently hydrogen or lower alkyl and R is a polyalkyl or polyalkyloxycarbonyl group. The compounds of formula I are useful as fuel additives for the prevention and control of engine deposits.
摘要:
Compounds having the formula: and fuel soluble salts thereof; wherein R 1 is nitro or -(CH 2 ) x -NR 4 R 5 , wherein R 4 and R 5 are independently hydrogen or lower alkyl and x is 0 or 1; R 2 is hydrogen, hydroxy, nitro, or -NR 6 R 7 wherein R 6 and R 7 are independently hydrogen or lower alkyl and R is a polyalkyl or polyalkyloxycarbonyl group. The compounds of formula I are useful as fuel additives for the prevention and control of engine deposits.
摘要翻译:式(I)化合物或其燃料可溶性盐是新的; 其中R1 =硝基或(CH2)xNR4R5; R4和R5各自为H或1-6C烷基; x = 0或1; R2 = H,羟基,硝基或NR6R7; R6和R7各自为H或1-6C烷基; R = R 3或C(O)OR 3; 和R3 =平均分子量的聚烷基。 450-5000。 还要求的是:(i)燃料组合物,其包含在汽油或柴油范围内沸腾的主要量的烃和足以控制发动机沉积物的量(I); 和(ii)燃料浓缩物包含b的惰性稳定的亲油有机溶剂。 PT。 150-400°F和10-70wt%(I)。
摘要:
Disclosed are an N-benzylaniline derivative and uses thereof. The derivative is a compound represented by formula I or a pharmaceutically acceptable salt thereof. The compound has an action of protecting against cerebral ischemia/reperfusion injury and an analgesic action for chronic pathologic pains, and may be used to prepare drugs for cerebral apoplexy, neuropathic pain, and inflammatory pain. Moreover, because of the unique mechanism of action of the compound, the compound can be used to prepare drugs for epilepsy, affective disorder, and neurodegenerative diseases.
摘要:
The present invention is related to new fluorescein derivatives, the method for producing such derivatives and their use for the synthesis of fluorogenic peptides and in particular protease substrates and peptide ligands.
摘要:
Fuel compositions containing a major amount of hydrocarbons boiling in the gasoline or diesel range and an effective deposit-controlling amount of a poly(oxyalkylene) aromatic ester having formula (I) where A1 is nitro, amino, N-alkylamino wherein the alkyl group contains 1 to 6 carbon atoms, or N,N-dialkylamino wherein each alkyl group independently contains 1 to 6 carbon atoms; R1 and R2 are independently hydrogen, hydroxy, lower alkyl, or lower alkoxy; R3 and R4 are independently hydrogen or lower alkyl, and each R3 and R4 is independently selected in each -O-CHR3-CHR4- unit; R5 is hydrogen, alkyl having 1 to 100 carbon atoms, phenyl, aralkyl having 7 to 100 carbon atoms or alkaryl having 7 to 100 carbon atoms, or an acyl group of formula (a) or (b) where R6 is alkyl having 1 to 30 carbon atoms, phenyl, aralkyl having 7 to 36 carbon atoms or alkaryl having 7 to 36 carbon atoms; R7 and R8 are independently hydrogen, hydroxy, lower alkyl, or lower alkoxy; A2 is a nitro, amino, N-alkylamino wherein the alkyl group contains 1 to 6 carbon atoms, or N,N-dialkylamino wherein each alkyl group independently contains 1 to 6 carbon atoms; n is an integer from 5 to 100; and x and y are each independently integers from 0 to 10.
摘要:
A dermatologic preparation containing at least one of the benzoic acid derivatives represented by general formula (I) and pharmacologically acceptable salts thereof, having a sufficient effect of inhibiting sebum secretion and being free from side effects, thus being safe for the human body, wherein R represents -OH, -OR or -NHR ; R represents hydrogen, lower alkyl or lower alkoxy; R represents -OR or (II); R represents alkyl, alkenyl or hydroxyalkyl; R represents C4-C10 linear or branched, saturated or monounsaturated alkyl or cycloalkylalkyl; X represents -O- or -NH-; and n represents 1 or 2.
摘要:
A dermatologic preparation containing at least one of the benzoic acid derivatives represented by general formula (I) and pharmacologically acceptable salts thereof, having a sufficient effect of inhibiting sebum secretion and being free from side effects, thus being safe for the human body, wherein R¹ represents -OH, -OR³ or -NHR³; R² represents hydrogen, lower alkyl or lower alkoxy; R represents -OR⁴ or (II); R³ represents alkyl, alkenyl or hydroxyalkyl; R⁴ represents C₄-C₁₀ linear or branched, saturated or monounsaturated alkyl or cycloalkylalkyl; X represents -O- or -NH-; and n represents 1 or 2.
摘要翻译:一种皮肤病学制剂,含有至少一种通式(I)表示的苯甲酸衍生物及其药理学上可接受的盐,其具有足够的抑制皮脂分泌并且没有副作用的效果,因此对人体来说是安全的,其中R 1表示-OH,-OR 3或-NHR 3; R 2表示氢,低级烷基或低级烷氧基; R表示-OR 4或(II); R 3表示烷基,烯基或羟烷基; R 4表示C 4 -C 10直链或支链,饱和或不饱和的烷基或环烷基烷基; X表示-O-或-NH-; 且n表示1或2.
摘要:
The disclosure provides methods of use of certain compounds that are useful for treating certain symptoms of endocrine disturbances, and in particular those associated with hot flashes.