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公开(公告)号：EP0441876A4
公开(公告)日：1992-10-07
申请号：EP89912855
申请日：1989-11-02
IPC分类号： A01N29/04 , A01N29/08 , A01N31/06 , A01N37/08 , A01N37/34 , A01N37/36 , A01N43/20 , B01J31/04 , C07B61/00 , C07C23/28 , C07C23/38 , C07C35/37 , C07C35/52 , C07C43/192 , C07C61/15 , C07C61/40 , C07C62/06 , C07C62/12 , C07C62/32 , C07C62/34 , C07C69/00 , C07C69/65 , C07C69/753 , C07C255/47 , C07D303/08 , C07D303/10
CPC分类号： C07C69/00 , A01N29/08 , A01N31/06 , A01N37/08 , A01N37/34 , A01N37/36 , A01N43/20 , C07C23/28 , C07C23/38 , C07C35/37 , C07C43/192 , C07C61/15 , C07C61/40 , C07C62/06 , C07C62/12 , C07C62/32 , C07C62/34 , C07C255/47 , C07C2602/42 , C07C2603/00 , C07C2603/68 , C07D303/08 , C07D303/10
摘要： Novel pesticidal compositions, which are characterized by biodegradability and do not bioaccumulate to an unacceptable level in fats and tissues of animals, fowl and fish, containing active compounds and optionally a carrier suitable for administering said compounds to a pest by contact, ingestion or inhalation, are disclosed. Such compositions comprise in addition to the carrier compounds of formula (I), where R is H, Cl or other Hal, hydroxyl, lower alkoxyl, lower alkyl, cyano, CONR2 or NR2, where R2 is H or lower alkyl; X and Y may be R, and when taken together may be -0- or a saturated or unsaturated monocyclic or bicyclic group which may be substituted with R, epoxide, carboxy or carboxymethyl group; and the unsaturated analogs thereof wherein the unsaturation occurs at at least one of the 2 or the 5 positions, and wherein unsaturation may occur optionally in the ring formed by X and Y taken together; with the further proviso that said compound has between 4 and 6 halogens; and a carrier for said compound. Methods of using such pesticides to kill or disable pests are disclosed. Certain novel compounds within the group and novel methods of making said compounds are disclosed.
摘要翻译： 新型杀虫剂组合物，其特征在于生物降解性，并且在生物活性化合物和任选的适于通过接触，摄入或吸入向所述化合物施用所述化合物的动物，家禽和鱼的脂肪和组织中未生物累积到不可接受的水平， 被披露。 这些组合物除了式（I）的载体化合物外，其中R是H，Cl或其它Hal，羟基，低级烷氧基，低级烷基，氰基，CONR2或NR2，其中R2是H或低级烷基; X和Y可以是R，并且一起可以是-O-或可以被R，环氧化物，羧基或羧甲基取代的饱和或不饱和的单环或双环基团; 和其不饱和类似物，其中不饱和键在2或5个位置中的至少一个上发生，并且其中不饱和可任选地在X和Y所形成的环中一起发生; 进一步的条件是所述化合物具有4至6个卤素; 和所述化合物的载体。 公开了使用这种杀虫剂杀死或禁用害虫的方法。 本发明公开了该组内某些新化合物及其制备方法。
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公开(公告)号：EP0897264A4
公开(公告)日：1999-09-08
申请号：EP97921349
申请日：1997-04-22
申请人： HENKEL CORP
发明人： WULFF HARALD P
IPC分类号： A23L3/3472 , A23L3/44 , A61K8/97 , A61K9/00 , A61K36/87 , A61K47/46 , A61Q1/00 , A61Q19/00 , A01N65/00 , A61K6/00 , A61K7/00 , A61K9/14 , A61K35/78 , A61K39/385 , A61K47/00 , C07C62/06 , C07C62/12 , C07C62/30 , C07C65/105
CPC分类号： A61K9/0014 , A23L3/3472 , A23L3/44 , A61K8/97 , A61K36/87 , A61K47/46 , A61K2800/522 , A61Q19/00 , A61K2300/00
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公开(公告)号：EP1916234A4
公开(公告)日：2010-07-14
申请号：EP06782304
申请日：2006-07-28
IPC分类号： C07C69/757 , A61K31/192 , A61K31/216 , A61K31/337 , A61K31/382 , A61K31/426 , A61P3/10 , A61P43/00 , C07C62/12 , C07C229/46 , C07D277/20 , C07D277/42 , C07D305/06 , C07D335/02
CPC分类号： C07C229/46 , C07C62/34 , C07C69/757 , C07C2601/02 , C07D277/20 , C07D277/42 , C07D305/06 , C07D335/02
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公开(公告)号：EP1916234B1
公开(公告)日：2014-11-12
申请号：EP06782304.7
申请日：2006-07-28
发明人： YASUMA, T., c/o TAKEDA PHARMACEUTICAL COMPANY LTD. , NEGORO, N., c/o TAKEDA PHARMACEUTICAL COMPANY LTD.
IPC分类号： C07C69/757 , A61K31/192 , A61K31/216 , A61K31/337 , A61K31/382 , A61K31/426 , A61P3/10 , A61P43/00 , C07C62/12 , C07C229/46 , C07D277/20 , C07D277/42 , C07D305/06 , C07D335/02 , C07C62/34
CPC分类号： C07C229/46 , C07C62/34 , C07C69/757 , C07C2601/02 , C07D277/20 , C07D277/42 , C07D305/06 , C07D335/02
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公开(公告)号：EP1916234A1
公开(公告)日：2008-04-30
申请号：EP06782304.7
申请日：2006-07-28
发明人： YASUMA, T., c/o TAKEDA PHARMACEUTICAL COMPANY LTD. , NEGORO, N., c/o TAKEDA PHARMACEUTICAL COMPANY LTD.
IPC分类号： C07C69/757 , A61K31/192 , A61K31/216 , A61K31/337 , A61K31/382 , A61K31/426 , A61P3/10 , A61P43/00 , C07C62/12 , C07C229/46 , C07D277/20 , C07D277/42 , C07D305/06 , C07D335/02
CPC分类号： C07C229/46 , C07C62/34 , C07C69/757 , C07C2601/02 , C07D277/20 , C07D277/42 , C07D305/06 , C07D335/02
摘要： A compound of the formula (I):
wherein each symbol is as defined in the description, a salt thereof, and a prodrug thereof of the present invention unexpectedly have a superior GPR40 receptor agonist activity and superior properties as pharmaceutical products such as stability and the like, and can be safe and useful pharmaceutical agents for the prophylaxis or treatment of GPR40 receptor-related pathology or diseases in mammals.摘要翻译： 式（I）化合物：其中每个符号如本说明书中所定义，其盐及其前药意外地具有优异的GPR40受体激动剂活性和作为药物稳定性等优异性能， 并且可以是用于预防或治疗哺乳动物中GPR40受体相关病理学或疾病的安全有用的药物。
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公开(公告)号：EP0771196A4
公开(公告)日：1997-09-03
申请号：EP95929416
申请日：1995-08-07
申请人： LILLY CO ELI
发明人： ARNOLD MACKLIN BRIAN , BLEISCH THOMAS J , HELTON DAVID REED , KALLMAN MARY JEANNE , ORNSTEIN PAUL LESLIE , SCHOEPP DARRYLE DARWIN , TIZZANO JOSEPH PATRICK
IPC分类号： B60T8/34 , A61K31/195 , A61K31/34 , A61K31/35 , A61K31/352 , A61K31/38 , A61K31/381 , A61P25/00 , A61P25/28 , A61P43/00 , B60T8/36 , C07C62/12 , C07C62/18 , C07C62/22 , C07C62/26 , C07C227/24 , C07C227/30 , C07C229/46 , C07D207/24 , C07D211/34 , C07D233/72 , C07D233/76 , C07D311/58 , C07D311/80 , C07D333/24 , C07D521/00 , F16K27/00 , F16K27/02 , F16K31/06 , A61K31/19 , C07C61/04 , C07C61/16
CPC分类号： C07D311/80 , C07C62/12 , C07C62/18 , C07C62/22 , C07C62/26 , C07D211/34 , C07D233/76
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