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公开(公告)号：EP4382104A1
公开(公告)日：2024-06-12
申请号：EP22306788.5
申请日：2022-12-05
发明人： GRECO, Céline
IPC分类号： A61K31/4453 , A61K9/00 , A61P17/00
CPC分类号： A61K31/4453 , A61K9/0014 , A61P17/00
摘要： The present invention relates to a compound selected from dyclonine, a dyclonine analog and a pharmaceutically acceptable salt thereof, or a composition comprising such a compound, for use in the topical treatment and prevention of hand-foot syndrome.
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公开(公告)号：EP3383378B1
公开(公告)日：2024-04-17
申请号：EP16823075.3
申请日：2016-12-01
IPC分类号： A61K31/26 , A61K31/145 , A61K31/166 , A61K31/216 , A61K31/22 , A61K31/27 , A61K31/325 , A61K31/336 , A61K31/351 , A61K31/439 , A61K31/4425 , A61K31/4453 , A61K31/452 , A61K31/5375 , A61P9/00
CPC分类号： A61K31/145 , A61K31/166 , A61K31/216 , A61K31/22 , A61K31/325 , A61K31/351 , A61K31/5375 , A61K31/26 , A61K31/27 , A61K31/4453 , A61K31/336 , A61K31/439 , A61K31/4425 , A61K31/452 , C07D211/46 , C07D213/04 , C07D213/30 , C07D213/65 , C07D295/13 , C07D303/36 , C07D453/02 , A61P9/00 , Y02A50/30
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公开(公告)号：EP4284360A1
公开(公告)日：2023-12-06
申请号：EP22702947.7
申请日：2022-01-28
申请人： Advanced Biodesign
发明人： PEREZ, Mileidys , MARTIN, Guillaume
IPC分类号： A61K31/265 , A61K31/4453 , A61K31/5375 , A61P35/00
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公开(公告)号：EP3840749B1
公开(公告)日：2023-08-09
申请号：EP19853073.5
申请日：2019-08-20
IPC分类号： A61K31/132 , A61K31/198 , A61K31/4035 , A61K31/4245 , A61K31/428 , A61K31/433 , A61K31/4453 , A61K31/485 , A61K31/506 , A61K31/55 , A61K31/635 , A61K45/06 , A61P9/10
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公开(公告)号：EP4035666A1
公开(公告)日：2022-08-03
申请号：EP21305123.8
申请日：2021-01-29
申请人： Advanced Biodesign
发明人： PEREZ, Mileidys , MARTIN, Guillaume
IPC分类号： A61K31/265 , A61K31/4453 , A61K31/5375 , A61P35/00
摘要： The present invention relates to aminotiolesters compounds for use for modulating the immune response in a subject. In particular, said compounds are comprised in a lipidic nanocapsule. The invention further relates to a pharmaceutical composition and to combination products comprising at least one aminothiolester compound and an immune checkpoint inhibitor, and their use for the treatment of cancer.
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公开(公告)号：EP3503883B1
公开(公告)日：2022-05-04
申请号：EP17842920.5
申请日：2017-08-23
发明人： HUANG, Niu , PENG, Shiming
IPC分类号： A61K31/277 , A61K31/04 , A61P27/02 , A61K31/397 , A61K31/426 , A61K31/428 , A61K31/433 , A61K31/4402 , A61K31/4453 , A61K31/4965 , A61K31/505 , A61K31/535 , A61K45/06
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公开(公告)号：EP3939968A1
公开(公告)日：2022-01-19
申请号：EP20784904.3
申请日：2020-03-30
申请人： Medicinal Bioconvergence Research Center , Dongguk University Industry-Academic Cooperation Foundation
发明人： KIM, Sunghoon , KIM, Dae Gyu , LEE, Kyeong , KIM, Minkyoung
IPC分类号： C07D295/18 , A61K31/5375 , A61K31/216 , A61K31/36 , A61K31/40 , A61K31/404 , A61K31/4168 , A61K31/4196 , A61K31/426 , A61K31/4453
摘要： The present invention pertains to a novel compound having anticancer activity, and a method for producing same, and more specifically, to a novel compound that exhibits excellent anticancer activity by inhibiting the expression of AIMP2-DX2, and a method for producing same. The compound represented by chemical formula 1 according to the present invention is highly effective in inhibiting the expression of AIMP2-DX2, and thus can be very advantageously used for the development of agents for treating various diseases, in particular cancer, caused by AIMP2-DX2.
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公开(公告)号：EP3778571A1
公开(公告)日：2021-02-17
申请号：EP19774270.3
申请日：2019-03-26
申请人： Bioway, Inc.
IPC分类号： C07D211/22 , A61K31/4453 , A61K31/496 , A61K31/5375 , C07D241/04 , C07D265/30 , A23L33/10 , A61P3/04 , A61P3/10
摘要： The present application relates to a novel pentadienoyl compound and a pharmaceutical composition including the same. The pentadienoyl compound of the present application may be used to prevent or treat fatty liver and fatty liver-related disease by inhibiting lipogenesis and lipid accumulation in cells and activating lipid metabolism. In addition, the pentadienoyl compound of the present application may increase a SIRT1 expression level in cells or SIRT1 activity, and thus may be used to prevent or treat a SIRT1-mediated disease. In addition, the pentadienoyl compound of the present application may reduce a CK2 expression level in cells or CK2 activity, and thus may be used to prevent or treat a CK2-mediated disease.
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9.发明公开
公开(公告)号：EP3774730A1
公开(公告)日：2021-02-17
申请号：EP19796802.7
申请日：2019-05-02
发明人： KWON, Byoung-Mog , HAN, Dong Cho , YOON, Yae Jin , LEE, Yu Jin , CHOI, Jiyoun , LEE, Sangku
IPC分类号： C07D211/14 , A61K31/4453 , A61K45/06 , A61P35/00
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公开(公告)号：EP3305767B1
公开(公告)日：2020-09-09
申请号：EP15894366.2
申请日：2015-12-23
IPC分类号： C07D211/00 , A61K31/5377 , A61K31/40 , A61K31/551 , A61K31/4436 , A61K31/38 , A61K9/00 , A61P17/00 , A61P29/00 , A61K31/4178 , A61K31/4453 , A61K31/496 , A61K31/506
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