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    BIOAVAILABLE POLYAMINES
    4.
    发明公开
    BIOAVAILABLE POLYAMINES 审中-公开

    公开(公告)号：EP3785706A1

    公开(公告)日：2021-03-03

    申请号：EP20196042.4

    申请日：2017-03-20

    申请人： Aminex Therapeutics, Inc.

    发明人： BURNS, Mark R.

    IPC分类号： A61K9/20 ,  A61K9/28 ,  A61K38/45 ,  A23L33/00 ,  A61K45/06 ,  A61K31/78 ,  C07C237/10

    摘要： Disclosed herein are pharmaceutical salts of a cationic protonated polyamine pharmaceutical agent and an anionic organic carboxylate which is hydrophobic when in protonated form, particularly suited for oral administration, where these salts have good bioavailability in solid dosage forms and may be used in the treatment of cancer and other medical conditions for which the pharmaceutical agent is intended.

    ANTIVIRAL DRUG
    10.
    发明公开
    ANTIVIRAL DRUG 审中-公开
    抗病毒药物

    公开(公告)号：EP3111944A1

    公开(公告)日：2017-01-04

    申请号：EP15755180.5

    申请日：2015-02-26

    申请人： Shirotake, Shoichi

    发明人： OSHIMA, Syun-ichirou ,  IMAJOH, Masayuki ,  SHIROTAKE, Shoichi

    IPC分类号： A61K31/78 ,  A61K9/16 ,  A61K47/18 ,  A61K47/20 ,  A61K47/22 ,  A61K47/24 ,  A61K47/26 ,  A61K47/36 ,  A61P31/12 ,  A61P31/16 ,  A61P31/22 ,  C12N15/09

    CPC分类号： C08F122/32 ,  A01N37/34 ,  A01N37/44 ,  A61K9/1635 ,  A61K31/78 ,  A61K31/785 ,  A61K47/18 ,  A61K47/20 ,  A61K47/22 ,  A61K47/24 ,  A61K47/26 ,  A61K47/36 ,  A01N25/10 ,  A01N25/34

    摘要： Novel antiviral means is disclosed. The antiviral agent of the present invention comprises as an effective ingredient particles having a particle diameter of not more than 5 µm, wherein said particles are polymer particles whose repeat unit comprises a structure represented by a particular general formula, and wherein said particles do not contain an antiviral active component. The polymer particles are preferably cyanoacrylate polymer particles. The antiviral agent of the present invention shows adhesiveness to the surface (especially envelope) of virus particles, and destroys a normal virus particle structure to reduce or eliminate infectivity of the virus particles. Sanitary articles such as masks comprising the antiviral agent of the present invention can exert an excellent effect on prevention of infection with viruses such as influenza virus that occurs through droplet infection or airborne infection.

    摘要翻译： 公开了新的抗病毒手段。 本发明的抗病毒剂包含作为有效成分的粒径不大于5μm的颗粒，其中所述颗粒是其重复单元包含由特定通式表示的结构的聚合物颗粒，并且其中所述颗粒不含 抗病毒活性成分。 聚合物颗粒优选为氰基丙烯酸酯聚合物颗粒。 本发明的抗病毒剂显示出与病毒颗粒的表面（尤其是包膜）的粘附性，破坏正常的病毒颗粒结构以减少或消除病毒颗粒的感染性。 包含本发明的抗病毒剂的面罩等卫生洁具可以防止通过液滴感染或空气传播感染而发生的流感病毒等病毒感染的效果良好。