公开(公告)号：EP4389135A1

公开(公告)日：2024-06-26

申请号：EP22858629.3

申请日：2022-07-29

申请人： Korea Ginseng Corp.

发明人： IN, Gyo ,  SO, Seung-Ho ,  KIM, Jong Han ,  JANG, Kyoung Hwa ,  KOO, Gi-Bang ,  KWON, Han Ol ,  JEONG, Yoonseon ,  HAN, Byung Cheol

IPC分类号： A61K36/25 ,  A61P27/02 ,  A23L33/105

摘要： A composition containing a Dendropanax morbifera LEV. extract, of the present invention, has excellent activities of inhibiting the oxidation of A2E, inhibiting oxidized A2E-induced death of retinal pigmented epithelial cells, and inhibiting the accumulation of drusen, and thus can be used for preventing eye damage. In addition, a composition containing a Dendropanax morbifera LEV. extract, of the present invention, can be developed even into a therapeutic agent for various eye diseases and a health functional food.

公开(公告)号：EP4209225A1

公开(公告)日：2023-07-12

申请号：EP21863593.6

申请日：2021-08-31

申请人： Dalian Fusheng Natural Medicine Development Co., Ltd.

发明人： WANG, Shuo ,  FU, Li ,  FENG, Xue ,  LIU, Yang ,  LIN, Rongxin ,  HOU, Jirui ,  LU, Mingming ,  FU, Wenfei ,  LU, Qi ,  ZHOU, Qingfeng

IPC分类号： A61K36/634 ,  A61K36/25 ,  A61P31/12 ,  A61P29/00 ,  A61P37/04

摘要： The present invention discloses a composition of forsythia suspensa component and an optional panax ginseng component that can be used safely, efficiently and stably to achieve the antiviral, antipyretic, anti-inflammatory and/or immunity boosting effects, including forsythin, forsythin derivatives, and the composition of forsythin and phillygenin for the prevention and treatment of diseases associated with human cytomegalovirus infection, such as simple human cytomegalovirus infection or patients infected by human cytomegalovirus during the prevention and treatment of cardiovascular and cerebrovascular diseases, tumors, burns or AIDS or during the process of organ transplantation or during the perinatal period. Wherein, the process for preparing the composition of forsythia suspensa and panax ginseng components is simple, suitable for industrial production and easy to popularize.

公开(公告)号：EP4181931A1

公开(公告)日：2023-05-24

申请号：EP21749125.7

申请日：2021-07-14

申请人： Bimeda Animal Health Limited

发明人： SMITH, Brendan, Gerard ,  GUPTA, Sandeep ,  LAHMANN, Martina ,  HOFFMANN, Karl ,  FISHER, Maggie ,  BAIRD, Mark, Stephen

IPC分类号： A61K31/704 ,  A61K36/25 ,  A61P33/10

公开(公告)号：EP3939596A1

公开(公告)日：2022-01-19

申请号：EP20185806.5

申请日：2020-07-14

申请人： Bimeda Animal Health Limited

发明人： Smith, Brendan, Gerard ,  Gupta, Sandeep ,  Lahmann, Martina ,  Hoffmann, Karl ,  Fisher, Maggie ,  Baird, Mark, Stephen

IPC分类号： A61K31/704 ,  A61K36/25 ,  A61P33/10

摘要： A composition for use in treating helminth infestation in a mammal is a described. The composition comprises an antihelmintically effective amount of α-hederin and a pharmaceutically acceptable carrier. The α-hederin is provided as an ivy extract. Treatment of liver fluke and rumen fluke infestation in ruminants is described.

公开(公告)号：EP3406256B1

公开(公告)日：2020-11-18

申请号：EP17741609.6

申请日：2017-01-11

申请人： Yang Ji Chemical Co., Ltd. ,  Han Wha Pharma Co., Ltd.

发明人： KIM, Kyoung Rak ,  MOON, Hong Sik ,  KIM, Tae Wook ,  KIM, Sung Jun ,  YU, Se Mi ,  YOON, Yeong Cheol ,  KIM, Jong Hoon

IPC分类号： A61K36/185 ,  A61K36/25 ,  A61K9/08 ,  A61K47/36 ,  A61P11/00

公开(公告)号：EP3360563A1

公开(公告)日：2018-08-15

申请号：EP17155660.8

申请日：2017-02-10

申请人： Shin, Joon Shik

发明人： SHIN, Joon Shik ,  LEE, Jin Ho

IPC分类号： A61K36/65 ,  A61K35/64 ,  A61K36/11 ,  A61K36/46 ,  A61K36/21 ,  A61K36/254 ,  A61K36/238 ,  A61K36/25 ,  A61K36/23 ,  A61P19/00 ,  A61P29/00

CPC分类号： A61K36/65 ,  A61K35/63 ,  A61K36/21 ,  A61K36/23 ,  A61K36/238 ,  A61K36/25 ,  A61K36/254 ,  A61K36/46

摘要： The present invention relates to a pharmaceutical composition for preventing or treating inflammatory spine disease comprising Peony and Scolopendra subspinipes extract as an active ingredient, and the present inventors have confirmed that the mixed extract of Peony and Scolopendra subspinipes was effective in inhibiting the generation of nitrogen oxide and cytokines dose-dependently, and observed that ear edema in the mouse model induced with ear edema was alleviated by treatment of the mixed extract of Peony and Scolopendra subspinipes dose-dependently. Also, the mixed extract of Peony, and Scolopendra subspinipes, added with Cibotium barometz, Ostericum Koreanum, Eucommia ulmoides, Achyranthes, Acanthopanax, Saposhnikovia divaricata, and Aralia contientalis was confirmed to be most effective in inhibiting the inflammatory reaction, and the said mixed extract resulted in pain relief and disc improvement upon administration to lumbar herniated intervertebral disc patients via pharmacopuncture. Therefore, it is suggested that the pharmaceutical composition comprising of the extract of Peony and Scolopendra subspinipes of the present invention may be effectively used for the prevention or treatment of inflammatory spine disease and also be effectively used in pharmacopuncture for the prevention or treatment of inflammatory spine disease.

公开(公告)号：EP3003335A1

公开(公告)日：2016-04-13

申请号：EP14738394.7

申请日：2014-06-06

申请人： Bionorica SE

发明人： POPP, Michael

IPC分类号： A61K36/185 ,  A61K36/25 ,  A61K36/53

CPC分类号： A61K36/53 ,  A61K9/0014 ,  A61K36/185 ,  A61K36/25 ,  A61K2300/00

摘要： The invention relates to an extract made of thyme (
Thymus L. ) combined with primrose (
Primula veris ) or ivy (
Hedera helix ) for use as PDE-4 inhibitor in the prophylaxis and treatment of selected diseases and to a corresponding drug and the use thereof.

公开(公告)号：EP2944316A1

公开(公告)日：2015-11-18

申请号：EP14737578.6

申请日：2014-01-10

申请人： Korea Institute Of Oriental Medicine

发明人： KIM, Jin Sook ,  KIM, Jung Hyun ,  KIM, Chan Sik ,  KIM, Young Sook ,  SHON, Eun Jin ,  LEE, Yun Mi ,  JUNG, Dong Ho ,  LEE, Ik Soo ,  JO, Gyu Hyeong ,  KIM, Joo Hwan

IPC分类号： A61K36/25 ,  A61K36/718 ,  A61P3/00 ,  A61P9/00

CPC分类号： A61K36/25 ,  A23L33/105 ,  A23V2002/00 ,  A61K31/155 ,  A61K36/16 ,  A61K36/45 ,  A61K36/482 ,  A61K36/488 ,  A61K36/708 ,  A61K36/718 ,  A61K36/73 ,  A61K36/87 ,  A61K2300/00

摘要： The present invention relates to a pharmaceutical composition and a health functional food composition for prevention, treatment or amelioration of diabetic complications or angioedema containing a mixed extract of Hedera helix leaves and Coptis chinensis as an active ingredient. More specifically, the present invention relates to a pharmaceutical composition and a health functional food composition for prevention, treatment or amelioration of diabetic complications or angioedema further containing an extract of Rheum palmatum , Puerariae radix, Ginkgo leaves, Cassiae semen , blueberry, bilberry, raspberry, or grape seeds as an active ingredient, in addition to the mixed extract of Hedera helix leaves and Coptis chinensis.

摘要翻译： 本发明涉及一种药物组合物和用于预防，治疗或糖尿病并发症或血管性水肿含常春藤叶和黄连的混合提取物作为活性成分的的改善的健康功能食品组合物。 更具体地，本发明涉及一种药物组合物和用于预防，治疗或糖尿病并发症或血管性水肿还含有的改善，基数在掌叶大黄葛根，银杏叶，决明子，蓝莓，覆盆子，覆盆子提取物的健康功能食品组合物 或葡萄籽作为活性成分的，除了常春藤叶和黄连的混合提取物。

公开(公告)号：EP2908835A1

公开(公告)日：2015-08-26

申请号：EP13789203.0

申请日：2013-10-17

申请人： MONTERO GIDA SANAYI VE TICARET A.S.

发明人： CIFTER, Ümit ,  ARABACIOGLU, Nazife ,  TOKER, Özlem

IPC分类号： A61K36/185 ,  A61K36/61 ,  A61K36/25 ,  A61K47/26 ,  A61P11/00 ,  A61K36/28

CPC分类号： A61K36/25 ,  A61K9/0095 ,  A61K36/185 ,  A61K47/12 ,  A61K47/26 ,  A61K2236/00 ,  A61K2300/00

摘要： The present invention relates to a formulation comprising extracts of Hedera helix and Pelargonium sidoides for use in the treatment, prevention of, or the alleviation and/or elimination of the symptoms of various respiratory tract diseases, as well as a method for preparing this formulation.

公开(公告)号：EP2268295B1

公开(公告)日：2015-03-25

申请号：EP09716101.2

申请日：2009-02-27

申请人： Valeant Canada LP

发明人： ADAMKO, Darryl, J. ,  ROSENTHAL, Kenneth, L. ,  SHAN, Jacqueline ,  WU, Yingqi ,  SUTHERLAND, Sharla

IPC分类号： A61K36/25 ,  A61P37/04

CPC分类号： A61K36/258 ,  A61K36/25