摘要:
The present invention relates to novel pyridazine derivatives of formula (I) as active ingredients which have microbiocidal activity, in particular fungicidal activity: wherein R1 is hydrogen, C1-C6alkyl, C1-C8haloalkyl or C3-C6cycloalkyl; R2 is cycloalkyl, cycloalkylalkyl, halocycloalkyl, cycloalkoxy, halocycloalkoxy, cycloalkylalkoxy, halocycloalkylalkoxy, alkoxyalkyl, cycloalkoxyalkoxyalkyl, haloalkoxyalkyl, trialkylsilyl, alkylthioalkyl, haloalkylthioalkyl, cycloalkylthio, halocycloalkylthio, cycloalkylalkylthio, halocycloalkylalkylthio, alkylsulfinylalkyl, alkylsulfonylalkyl, alkylsulfinyl, haloalkylsulfinyl, alkylsulfonyl, haloalkylsulfonyl, C2-C6alkenyl, C2-C6alkynyl, optionally substituted arylsulfonyl, optionally substituted aryloxy, optionally substituted heteroaryloxy, optionally substituted arylthio, optionally substituted heteroarylthio; or R2 together with an adjacent carbon atom forms an optionally substituted fused ring; R3 is an optionally substituted aryl; R4 is hydrogen, halogen, C1-C6alkyl, C1-C6haloalkyl, C1-C8alkoxy, C1-C6haloalkoxy, hydroxy or cyano; and n is a whole number from 1 to 4; or an agrochemically usable salt form thereof.
摘要:
The invention relates to pyridazines of the formula (I), in which the substituents are defined according to the description, methods and intermediate products for the production of said compounds, agents containing the same and the use thereof for controlling plant-pathogenic fungi, and the use of pyridazines for the production of a drug for the treatment of cancer.
摘要:
Compounds of the general formula (I) or salts thereof; and drugs containing the compounds or the salts: (I) [wherein R1 is optionally substituted phenyl, pyridyl, or the like; R2 is lower alkoxy, lower alkylthio, lower alkylsulfinyl, lower alkylsulfonyl, or the like; R3 is hydrogen, lower alkoxy, or the like; and R4 is hydrogen, substituted alkyl, or the like]. The compounds exhibit an excellent interleukin 1ß production inhibiting activity and are useful as preventive and therapeutic drugs for immunologic diseases, inflammatory diseases, ischemic disease, and so on.
摘要:
A compound represented by general formula (I), its salt, production thereof, and insecticide containing the same wherein R1 represents a 5- or 6-membered nitrogenous aromatic heterocyclic group which may be substituted; X represents alkylene or alkylidene; R2 represents hydrogen, optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, aryl or -Y-R3; Y represents O, S(O)l, CO or CO2; l represents 0, 1 or 2; R3 represents hydrogen, optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl or aryl; A, B and D represent each independently an optionally substituted carbon atom or hetero-atom or a single bond; E represents CO or CS; Q represents hydrogen, optionally substituted alkyl, alkenyl, alkynyl, aryl, nitro, halogen or Z-R4; Z represents CO, CO2 or S(O)m; m represents 0, 1 or 2; and R4 represents optionally substituted alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl or aryl.