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    ASSAY FOR ENTACTOGENS
    6.
    发明授权
    ASSAY FOR ENTACTOGENS 有权

    公开(公告)号：EP1701949B8

    公开(公告)日：2018-06-06

    申请号：EP04813878.8

    申请日：2004-12-13

    申请人： Siemens Healthcare Diagnostics Inc.

    发明人： ZHENG, Yi, Feng ,  LIU, Hshiou-Ting ,  YANG, Yali

    IPC分类号： C07D317/48 ,  C07D317/58 ,  C07D405/12 ,  C07K16/44 ,  G01N33/532 ,  G01N33/94 ,  A61K39/385

    CPC分类号： C07D317/48 ,  C07D317/58 ,  C07D405/12 ,  C07K16/44 ,  G01N33/532 ,  G01N33/946

    摘要： Methods, compositions and kits are disclosed. The methods are directed to determining the presence of entactogen analytes such as, for example, 3,4-methylenedioxyamphetamine (MDA), 3,4-methylenedioxy-methamphetamine (MDMA), 3,4-methylenedioxy-ethylamphetamine (MDEA) and 4-hydroxy-3-methoxy-methamphetamine (HMMA). The method comprises providing in combination in a medium (i) a sample suspected of containing the compound and (ii) an antibody raised against a compound of Formula I that comprises a protein. The medium is examined for the presence a complex comprising the compound and the antibody where the presence of such as complex indicates the presence of the compound in the sample. In one aspect of the above embodiment, the combination further comprises a label conjugate of the compound Formula I.