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公开(公告)号:EP4208186A1
公开(公告)日:2023-07-12
申请号:EP21786091.5
申请日:2021-09-06
IPC分类号: A61K38/16 , A61P9/10 , A61P15/06 , A61P17/02 , A61P25/28 , C07K14/16 , A61K38/18 , C07K14/155 , C07K14/505
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公开(公告)号:EP4163290A1
公开(公告)日:2023-04-12
申请号:EP22195110.6
申请日:2013-01-28
摘要: The present invention relates to novel immunogens based on overlapping peptides (OLPs) and peptides derived therefrom useful for the prevention and treatment of AIDS and its related opportunistic diseases. The invention also relates to isolated nucleic acids, vectors and host cells expressing these immunogens as well as vaccines including said immunogens.
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公开(公告)号:EP4110384A2
公开(公告)日:2023-01-04
申请号:EP21761505.3
申请日:2021-02-26
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公开(公告)号:EP3964225A1
公开(公告)日:2022-03-09
申请号:EP20194685.2
申请日:2020-09-04
IPC分类号: A61K38/16 , A61P9/10 , A61P15/06 , A61P17/02 , A61P25/28 , C07K14/16 , A61K38/18 , C07K14/155 , C07K14/505
摘要: The present invention relates to a peptide, or derivative thereof, having length equal to or lower than 30 amino acids, and comprising any one of SEQ ID Nos. 2, 3, 9, 10, 13, 14, 15 or 16 or a conservative variant thereof, for use as a medicament, preferably for use in the treatment of conditions associated to/caused by deficient angiogenesis or conditions beneficing from increased angiogenesis.
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公开(公告)号:EP3886890A1
公开(公告)日:2021-10-06
申请号:EP19886189.0
申请日:2019-11-19
IPC分类号: A61K38/16 , A61K38/45 , A61K39/385 , A61K39/395 , A61P37/02 , C07K14/155 , C07K14/16 , C07K14/725 , C07K14/73
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公开(公告)号:EP3860649A1
公开(公告)日:2021-08-11
申请号:EP19795609.7
申请日:2019-09-30
申请人: UNIVERSITE DE BORDEAUX , Centre national de la recherche scientifique , Centre Hospitalier Universitaire de Bordeaux
发明人: FLEURY, Hervé
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公开(公告)号:EP3511420B1
公开(公告)日:2021-04-07
申请号:EP19157170.2
申请日:2011-09-26
发明人: HOLMES, Michael C. , WANG, Jianbin
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公开(公告)号:EP2900697B1
公开(公告)日:2020-08-05
申请号:EP13841990.8
申请日:2013-09-27
发明人: WANG, Yu Tian , FAN, Xuelai , JIN, Jack Wuyang
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公开(公告)号:EP3659435A1
公开(公告)日:2020-06-03
申请号:EP19198486.3
申请日:2010-05-26
发明人: BRETON, Louis Randall , CHEN, Irvin , AN, Dong Sung , SYMONDS, Geoffrey P. , BOYD, Maureen , MILLINGTON, Michelle L.
IPC分类号: A01K67/027 , A61K35/28 , A61K48/00 , C07K14/00 , C07K14/16 , C07K14/47 , C12N9/90 , C12N15/85 , C12N15/867 , C12N15/113
摘要: The present invention provides an expression vector for preventing or inhibiting HIV entry, fusion or replication in mammalian cells. In particular, the invention provides a recombinant retroviral vector that encodes an inhibitor of a HIV co-receptor, such as CCR5 or CXCR4, and a protein that inhibits HIV fusion to target cells and/or HIV replication. Pharmaceutical compositions comprising such constructs and methods of use thereof to prevent or treat HIV infection in a patient are also disclosed.
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