公开(公告)号：JP2005523305A

公开(公告)日：2005-08-04

申请号：JP2003580312

申请日：2002-04-03

Applicant: チョン クン ダン ファーマシューティカル コープ.

Inventor： スン キル アン ,  ス キョン イ ,  ジョン レ イム ,  ジェ ヒョン キム ,  ヒ ジョン シン ,  ウォン キュ チェ ,  チュン イル ホン

IPC: A61K9/19 ,  A61K31/336 ,  A61K47/40 ,  A61P35/00 ,  A61P35/04 ,  C07D303/16 ,  C07D303/20 ,  C07D303/28 ,  C07D303/36 ,  C07D407/14 ,  C08B37/16

CPC classification number: A61K47/48969 ,  A61K9/0019 ,  A61K31/336 ,  A61K47/02 ,  A61K47/6951 ,  B82Y5/00 ,  C07D303/16 ,  C07D303/20 ,  C07D303/28 ,  C07D407/14 ,  C08B37/0015 ,  C08L5/16

Abstract: 本発明は、フマギロール誘導体又はその塩のヒドロキシプロピル-β-シクロデキストリン又はスルホブチルエーテル-7-β-シクロデキストリンとの包接化合物、及びこれを含む医薬組成物に関し、本発明の包接化合物は水での優れた溶解性及び安定性を有し毒性が低いため、抗癌剤又は癌転移阻害剤として有益である。

公开(公告)号：JP2005146253A

公开(公告)日：2005-06-09

申请号：JP2004180123

申请日：2004-06-17

Applicant: Tokuyama Corp ,  株式会社トクヤマ

Inventor： TAKENAKA JUNJI ,  YAMAMOTO HIROMASA ,  TANAKA KENJI

IPC: C07D303/28 ,  C07D305/06 ,  C08G59/04 ,  C08G65/18 ,  C08G65/26 ,  H01L23/28 ,  H01L33/56 ,  H01S5/022 ,  H01L33/00

Abstract: PROBLEM TO BE SOLVED: To provide an industrially useful novel curable compound having a polycyclic hydrocarbon structure in the molecule and excellent in such as light and heat resistances with abundant applicable techniques. SOLUTION: The curable polycyclic compound is shown by formula (1) [wherein A represents a bi- to hexa-valent group derived from the polycyclic hydrocarbon compounds; R 1 represents an optionally perfluorinated 1-4C alkyl group or fluorine atom; n represents an integer of 0-2; m represents an integer of 2-4; Y represents a formula (2) or (3) (wherein R 2 , R 3 , R 5 and R 6 are each independently represents hydrogen or a fluorine atom or a 1-4C alkyl group; R 4 represents a methyl or ethyl group; p and q each represent an integer of 0-4)]. COPYRIGHT: (C)2005,JPO&NCIPI

Abstract translation: 要解决的问题：提供在分子中具有多环烃结构的工业上有用的新型可固化化合物，并且具有优异的耐光性和耐热性，具有丰富的适用技术。 解决方案：可固化多环化合物由式（1）表示[其中A表示衍生自多环烃化合物的二价至六价基团; R 1表示任选全氟化的1-4C烷基或氟原子; n表示0-2的整数， m表示2-4的整数; Y表示式（2）或（3）（其中R 2 ，R 3 ，R 5 和R SP“各自独立地表示氢或氟原子或1-4C烷基; R”SP 4表示甲基或乙基; p和q各自表示0-4）]的整数。 版权所有（C）2005，JPO＆NCIPI

公开(公告)号：JP2003128660A

公开(公告)日：2003-05-08

申请号：JP2001324041

申请日：2001-10-22

Applicant: SHOWA DENKO KK

Inventor： OGUCHI WATARU ,  NISHI MAKOTO ,  TOTSUGI KOJI

IPC: C07D303/28 ,  B01J29/89 ,  C07B61/00 ,  C07D301/12 ,  C07D301/14 ,  C07D301/19 ,  C07D301/22

Abstract: PROBLEM TO BE SOLVED: To provide an oxidation method of a carbon-carbon double bond in which selective oxidation of the carbon-carbon double bond can be achieved and by which an oxidized compound of interest can be obtained with high selectivity and productivity, and also to provide a production method of an oxidized compound using the oxidation method. SOLUTION: The oxidation method is characterized by that the inversion rate of a compound having a carbon-carbon double bond is kept low during the method and that the unreacted compounds are separated from the product and reused in the oxidation reaction. The production method of an oxidized compound uses the oxidation method.

公开(公告)号：JP3370985B2

公开(公告)日：2003-01-27

申请号：JP2000549605

申请日：1999-05-11

Applicant: チョン クン ダン ファーマシューティカル コープ.

Inventor： ソーンキル アーン ,  ジュンウー キム ,  ヒョウンシク チュン ,  ナムソン チョイ ,  チェオルキュ ハン ,  チュンイル ホン ,  リュンキー ホン ,  セウンキー モーン ,  サンジョーン リー

IPC: C07D303/08 ,  A61K31/336 ,  A61P9/00 ,  A61P35/00 ,  A61P43/00 ,  C07D303/22 ,  C07D303/26 ,  C07D303/27 ,  C07D303/28 ,  C07D407/14

CPC classification number: C07D303/22 ,  C07D407/14

公开(公告)号：JP2993026B2

公开(公告)日：1999-12-20

申请号：JP1968490

申请日：1990-01-29

Applicant: SUMITOMO KAGAKU KOGYO KK

Inventor： SAITO NORIAKI ,  KANEKAWA SHUICHI ,  SAKAMOTO HIDE ,  IKUSHIMA TADASHI ,  NAKAJIMA NOBUYUKI ,  SHIMADA TAKESHI

IPC: C07D303/28 ,  C08G59/08

公开(公告)号：JP2872652B2

公开(公告)日：1999-03-17

申请号：JP17746297

申请日：1997-07-02

Applicant: HEKISUTO AG

Inventor： GERUTO UARUTSU ,  MIHYAERU HEENERU ,  GERUHARUTO BURINTODETSUPUKE ,  UARUTERU SUPURENGAA ,  MANFUREETO FUINKE ,  RYUUDEIGERU RENTSU

IPC: C07D317/36 ,  C07C67/00 ,  C07C239/00 ,  C07C269/00 ,  C07C271/20 ,  C07D303/28 ,  C08G18/06 ,  C08G18/32 ,  C08G18/64 ,  C08G18/70 ,  C08G18/80 ,  C08G18/83 ,  C08G59/02 ,  C08G59/40 ,  C08G71/04 ,  C09D5/44 ,  C09D175/04 ,  C09D175/12

公开(公告)号：JPH1171364A

公开(公告)日：1999-03-16

申请号：JP13357898

申请日：1998-05-15

Applicant: NAT STARCH CHEM INVEST

Inventor： NIKOLIC NIKOLA A ,  SCHULTZ ROSE ANN

IPC: C07D303/04 ,  C07D303/16 ,  C07D303/22 ,  C07D303/28 ,  C08G59/24 ,  C08G59/62 ,  C09D163/08 ,  C09J163/08

Abstract: PROBLEM TO BE SOLVED: To obtain the subject compound useful for adhesives or coating compositions by including a styrene oxide component having a specific structure. SOLUTION: This compound of the formula [R -R are each H, an aliphatic group, an alicyclic group or an aromatic group, in which the groups do not hinder the cationic polymerization of the epoxy functionality either through steric interaction or through the action of a Lewis base; (y) is 1-6; (ω) is 0-5], e.g. 1,3-diisopropenylbenzene dioxide. The compound of the formula is preferably obtained e.g. by treating the suspension of 1,3-diisopropenylbenzene and sodium bicarbonate in acetone : water (2:1) mixture with an aqueous solution containing potassium persulfate and subsequently subjecting the suspension to a reaction at a neutral pH at room temperature for about 3 hr.

公开(公告)号：JPH05287051A

公开(公告)日：1993-11-02

申请号：JP10905792

申请日：1992-04-03

Applicant: NIPPON KAYAKU KK

Inventor： MOGI SHIGERU ,  AKATSUKA YASUMASA ,  KUNIKATA KENJI ,  MORITA HIROMI ,  MIZOGUCHI KENICHI

IPC: C07D303/28 ,  C07D303/27 ,  C08G59/04 ,  C08G59/20 ,  C08G59/24 ,  H01L23/29 ,  H01L23/31

Abstract: PURPOSE:To obtain an epoxy resin composition having flow at ordinary temperature or low melt viscosity, can give a cured product excellent in heat and humidity resistance and is desirable for semiconductor sealing by mixing an epoxy resin of a specified formula with a curing agent. CONSTITUTION:The title composition is obtained by mixing an epoxy resin of formula I (wherein R1 and R2 are each H, halogen, 1-4C alkyl or aryl; and n is 1 or 2) with a curing agent and optionally a cure accelerator. The epoxy resin of formula I can be obtained by reacting a methylolated naphthol of formula II (wherein R1 and R2 are as defined above) with an epihalohydrin in the presence of an alkali metal hydroxide and a polar solvent. The resin composition containing the curing agent can easily be cured by a usual heating process or by uniformly dispersing or dissolving the respective components in a solvent or the like and removing the solvent or the like from the mixture. The obtained cured product is excellent in heat and humidity resistance and is a highly pure liquid resin, so that it can be highly filled with a filler when used for semiconductor sealing and can improve the reliability of the sealed device.

公开(公告)号：JPH02621A

公开(公告)日：1990-01-05

申请号：JP27758488

申请日：1988-11-04

Applicant: SHELL INT RESEARCH

Inventor： HARORUDO ERISON DE RA MAARE

IPC: C07D303/22 ,  C07C39/15 ,  C07C43/295 ,  C07C67/00 ,  C07C317/22 ,  C07C323/20 ,  C07D303/24 ,  C07D303/28 ,  C08G8/20 ,  C08G8/28 ,  C08G8/36 ,  C08G59/20 ,  C08G59/24

公开(公告)号：JPS60130579A

公开(公告)日：1985-07-12

申请号：JP23877483

申请日：1983-12-20

Applicant: MITSUI TOATSU CHEMICALS

Inventor： KAWAKAMI HARUHIKO ,  WATANABE KEISUKE ,  MASUDA TAKAYOSHI ,  SUEZAKI YUUJI

IPC: C07D301/28 ,  C07D303/04 ,  C07D303/22 ,  C07D303/28

Abstract: PURPOSE:To produce the titled substance by reacting allyl alcohol with epichlorohydrin and a solid alkali while removing produced water by the azeotropic distillation with epichlorohydrin, removing water from the azeotropic distillate, treating the distillate with a dehydration agent, and recycling to the reaction system. CONSTITUTION:1mol of allyl alcohol is made to react with 1-3mol of epichlorohydrin in the presence of 1.0-1.5mol of a solid alkali under boiling to obtain the objective substance. The produced water is removed from the system by forming an azeotropic mixture with the epichlorohydrin, water is separated from the distillate, and the distillate is treated with a dehydration agent and recycled to the reaction system. The reaction temperature is preferably 30-60 deg.C, and the reaction pressure is controlled (generally 40mm.Hg-1atm) so as to keep the boiling state at the above temperature. The reaction mixture may be added to 0.1-3.0g of an organic amine, a quaternary ammonium salt, etc. per 100g of allyl alcohol.