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    Method for producing protoisoflavones
    23.
    发明专利
    Method for producing protoisoflavones 审中-公开
    生产原生质体的方法

    公开(公告)号：JP2013060397A

    公开(公告)日：2013-04-04

    申请号：JP2011200276

    申请日：2011-09-14

    Applicant: Nisshin Pharma Inc ,  日清ファルマ株式会社

    Inventor： DAIKO YASUSHI ,  IKEMOTO HIROYUKI ,  YASUI KENSUKE

    IPC: C07D311/36 ,  A23L1/30 ,  A61K8/49 ,  A61K31/352 ,  A61P29/00 ,  C07B61/00

    Abstract: PROBLEM TO BE SOLVED: To provide isoflavone compounds having high bioactivity and a method for producing the same.SOLUTION: The method for producing isoflavone compounds includes subjecting a compound of formula (1) to light irradiation and/or heat-treatment in the presence of chlorophyll. In the formula, Rto Rand A are specific groups.

    Abstract translation: 待解决的问题：提供具有高生物活性的异黄酮化合物及其制备方法。 解决方案：异黄酮化合物的制备方法包括使式（1）化合物在叶绿素存在下进行光照射和/或热处理。 在公式中，R 1 到R 5 ，A是特定组。 版权所有（C）2013，JPO＆INPIT

    Sustained-release tablet
    25.
    发明专利
    Sustained-release tablet 有权
    可持续发布的平板电脑

    公开(公告)号：JP2012211192A

    公开(公告)日：2012-11-01

    申请号：JP2012170390

    申请日：2012-07-31

    Applicant: Kyorin Pharmaceutical Co Ltd ,  Nisshin Pharma Inc ,  日清ファルマ株式会社 ,  杏林製薬株式会社

    Inventor： SHIMIZU NOBORU

    IPC: A61K31/606 ,  A61K9/24 ,  A61K47/12 ,  A61K47/38

    Abstract: PROBLEM TO BE SOLVED: To provide a small-sized sustained-release tablet which contains a large number of sustained-release particles containing medicinal components, has excellent sustained-release properties and sufficient rigidity, and is easy in oral ingestion for a patient.SOLUTION: The sustained-release tablet contains the particles containing the medicinal components and having the sustained-release properties, and an antistatic agent and an excipient.

    Abstract translation: 待解决的问题：为了提供含有大量含有药物成分的缓释颗粒的小型缓释片剂，具有优异的持续释放性能和足够的刚性，并且易于口服摄入 患者。 缓释片剂含有含有药物成分并具有缓释性质的颗粒，以及抗静电剂和赋形剂。 版权所有（C）2013，JPO＆INPIT

    Composition for maintenance of muscle force and improvement of joint function
    26.
    发明专利
    Composition for maintenance of muscle force and improvement of joint function 审中-公开
    用于维持肌肉力量和改善关节功能的组合物

    公开(公告)号：JP2011246387A

    公开(公告)日：2011-12-08

    申请号：JP2010120820

    申请日：2010-05-26

    Applicant: Nisshin Pharma Inc ,  日清ファルマ株式会社

    Inventor： ASADA KENICHI ,  NIIMURA YUKI ,  MINEMURA TAKESHI ,  YAMADA KAZUHIKO

    IPC: A61K38/00 ,  A23K1/16 ,  A23L1/305 ,  A61P19/02 ,  A61P21/00

    Abstract: PROBLEM TO BE SOLVED: To develop and provide a natural material which is safe and inexpensive and can be ingested easily, routinely and continuously, which has a remarkable action of maintaining muscle force and improving joint function, and which is effective for prevention and/or improvement of various muscle force maintenance and joint functional disorders, especially, subjective symptoms resulting from problems with muscles or joints, e.g., joint pain, gait disorder, and decrease in joint movement range.SOLUTION: The composition for maintenance of muscle force and improvement of joint function comprises a wheat protein hydrolyzate, preferably, a wheat gluten hydrolyzate, and especially preferably, a peptide having an L-glutamine content of 15-60 mass% and an average molar weight of 200-100,000 daltons.

    Abstract translation: 要解决的问题：开发和提供安全，便宜，可以容易，常规，持续地摄取的天然材料，具有维持肌肉力量和改善关节功能的显着作用，有效预防 和/或各种肌肉力维持和关节功能障碍的改善，特别是由肌肉或关节问题引起的主观症状，例如关节疼痛，步态障碍和关节活动范围的减少。 解决方案：用于维持肌肉力和​​改善关节功能的组合物包括小麦蛋白水解物，优选小麦谷蛋白水解物，特别优选L-谷氨酰胺含量为15-60质量％的肽和 平均摩尔重量为200-100,000道尔顿。 版权所有（C）2012，JPO＆INPIT

    Anti-allergic agent
    27.
    发明专利
    Anti-allergic agent 审中-公开
    抗过敏剂

    公开(公告)号：JP2011153086A

    公开(公告)日：2011-08-11

    申请号：JP2010014468

    申请日：2010-01-26

    Applicant: Nisshin Pharma Inc ,  日清ファルマ株式会社

    Inventor： KANEKO AKIHIRO

    IPC: A61K36/48 ,  A23K1/14 ,  A23L1/30 ,  A23L2/52 ,  A61K8/97 ,  A61P11/06 ,  A61P17/00 ,  A61P27/14 ,  A61P37/08 ,  A61Q19/00

    Abstract: PROBLEM TO BE SOLVED: To provide a medicine that is easily produced, is readily taken and has anti-allergic actions. SOLUTION: A heat-treated blue soybean seed and/or its solvent extract is used as an active ingredient of the anti-allergic agent. Having extremely strong inhibitory action on IgE production, the blue soybean seed after heat-treatment is useful as an anti-allergic agent. COPYRIGHT: (C)2011,JPO&INPIT

    Abstract translation: 待解决的问题：提供易于生产，容易服用并具有抗过敏作用的药物。 解决方案：将热处理的蓝豆种子和/或其溶剂提取物用作抗过敏剂的活性成分。 对IgE产生具有非常强的抑制作用，热处理后的蓝色大豆种子可用作抗过敏剂。 版权所有（C）2011，JPO＆INPIT

    Sleep-improving composition
    30.
    发明专利
    Sleep-improving composition 审中-公开
    睡眠改善组合物

    公开(公告)号：JP2009013143A

    公开(公告)日：2009-01-22

    申请号：JP2007180266

    申请日：2007-07-09

    Applicant: Nisshin Pharma Inc ,  日清ファルマ株式会社

    Inventor： NISHIZAKA MAYU

    IPC: A61K38/00 ,  A61K33/06 ,  A61K33/14 ,  A61K33/26 ,  A61K33/30 ,  A61P25/20

    Abstract: PROBLEM TO BE SOLVED: To provide an excellent sleep-improving composition expressing high improving effect to sleep disorders, able to be safely and simply ingested daily, and imparting comfortable sleeping.
    SOLUTION: The sleep-improving composition comprises a hydrolyzate of casein which is a main ingredient of milk protein, and minerals daily ingested as supplements. While the composition expresses highly improved effect for sleep disorders such as waking at night and poor sleep, it is highly safe, and is able to be continuously digested daily.
    COPYRIGHT: (C)2009,JPO&INPIT

    Abstract translation: 要解决的问题：提供一种表现出对睡眠障碍的高度改善效果的优异的睡眠改善组合物，能够每天安全和简单地摄取，并赋予舒适的睡眠。 解决方案：睡眠改善组合物包含酪蛋白的水解产物，酪蛋白是乳蛋白的主要成分，每天摄取矿物质作为补充剂。 虽然该组合物对睡眠障碍（例如夜间醒来和睡眠不良）表现出高度改善的效果，但是它是高度安全的，并且能够每天不断消化。 版权所有（C）2009，JPO＆INPIT

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