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488 条记录 (耗时 0.018 秒)

    72.
    发明专利
    失效

    公开(公告)号：JPH0552841B2

    公开(公告)日：1993-08-06

    申请号：JP23311885

    申请日：1985-10-18

    申请人： CHOAY SA

    发明人： JANNKUROODO RORUMOO ,  JAN SHOAI

    IPC分类号： A61K31/715 ,  A61K38/01 ,  A61P7/02 ,  C08B37/00 ,  C08B37/10 ,  A61K31/725

    摘要： The method for producing the biologically active mucopolysaccharides comprises the treatment of heparin with depolymerizing agent followed by the separation of the end-product by ethanol precipitation. Sodium nitrite is used as depolymerizing agent. Heparin is used at the concentration of 5 mass %, sodium nitrite – 0.0435 M. The incubation is performed at pH 2.5 until NO-2 ions are no longer detectable. Prior to the separation of the end-product, pH of the reaction mixture is adjusted to 7 with sodium hydroxide solution. Ethanol is added at a 2:1 ratio to the reaction mixture. The precipitate is re-dissolved in the aqueous solution of NaCl at pH 3.8.

    BONE-FORTIFYING FOOD, FEED AND PHARMACEUTICAL
    74.
    发明专利
    BONE-FORTIFYING FOOD, FEED AND PHARMACEUTICAL 失效

    公开(公告)号：JPH04183371A

    公开(公告)日：1992-06-30

    申请号：JP30950490

    申请日：1990-11-15

    申请人： SNOW BRAND MILK PROD CO LTD

    发明人： TAKADA YUKIHIRO ,  KOBAYASHI NAOMICHI ,  MARUYAMA TAKASHI ,  YAHIRO MASATOSHI

    IPC分类号： A23C20/00 ,  A23J3/08 ,  A23J3/34 ,  A23L33/16 ,  A23L33/17 ,  A23L33/19 ,  A61K33/06 ,  A61K38/00 ,  A61K38/01 ,  A61K38/17 ,  A61P19/10 ,  A61P43/00 ,  C12P21/06

    摘要： PURPOSE:To prepare a bone-fortifying food, pharmaceutical or feed enabling the absorption of large amounts of whey protein and peptide and effective for fortifying the bone by using a water-soluble fraction of whey protein as a component. CONSTITUTION:Whey is a transparent yellowish green liquid obtained as a by-product of a cheese or casein preparation process and produced by adding an acid or rennet to milk or defatted milk and removing the coagulum from the mixture. Whey protein is a water-soluble protein produced by the ultrafiltration, reverse osmosis, chromatography, dialysis, etc., of the whey. The protein to be used in the present product is preferably a water-soluble fraction of a whey protein having a molecular weight of 10,000-45,000 and an isoelectric point of PI 3-8. In the case of performing an enzymatic decomposition with a proteinase, the solution or suspension of the protein is added with a proteinase and subjected to enzymatic decomposition. A proteinase- decomposition product having a molecular weight of about 20,000-300 can be produced by adjusting the solution or suspension of the protein to the optimum pH and optimum temperature for the enzyme, adding the enzyme to the solution, etc., and subjecting the solution to enzymatic reaction for a prescribed time in a stationary state or under stirring.

    IMPROVEMENT WITH REGARD TO ORGANIC PRODUCT
    77.
    发明专利
    IMPROVEMENT WITH REGARD TO ORGANIC PRODUCT 失效

    公开(公告)号：JPH03187348A

    公开(公告)日：1991-08-15

    申请号：JP26490090

    申请日：1990-10-01

    申请人： SANDO NIYUUTORISHIYON LTD

    发明人： JIYANNMOORISU KAAN ,  FURANSOWA MANDEII ,  ROI ROGAA

    IPC分类号： A23J1/20 ,  A23J3/08 ,  A23J3/34 ,  A23L1/305 ,  A61K38/00 ,  A61K38/01 ,  A61K38/17 ,  C12P21/06

    摘要： PURPOSE: To obtain an org. product which contains amino acids in the form of oligopeptide refined by hydrolyzing whey protein, does not contain a protein of a specific mol.wt., ensures absorption and does not contain allergen. CONSTITUTION: Protein whey factions of soybean protein, etc., are prepd. as an aq. soln. and are subjected to prehydrolysis with pepsin preferably at pH2 to 3. These fractions are then subjected to enzymatically hydrolysis with tripsn- chymotrispsin and are ultrafiltered, concentrated and dried, by which the desired product contg. the amino acid as the ologipeptide form having 4 to 10 amino acids at a ratio of 40 to 60wt.% without contg. the protein of the mol.wt. of >=60000 is obtd.

    ORAL INTAKE COMPOSITION
    78.
    发明专利
    ORAL INTAKE COMPOSITION 失效

    公开(公告)号：JPH01187067A

    公开(公告)日：1989-07-26

    申请号：JP25538387

    申请日：1987-10-09

    申请人： KANEBO LTD

    发明人： SUETSUNA KUNIO ,  MURAKAMI UMEJI ,  SUGAI RYUJI ,  TAKEMOTO TAIRA

    IPC分类号： A23L1/305 ,  A23L33/115 ,  A23L33/17 ,  A23L33/19 ,  A61K35/54 ,  A61K35/57 ,  A61K38/00 ,  A61K38/01 ,  A61K38/08 ,  A61K38/10 ,  A61K38/17 ,  A61K38/55 ,  A61P9/12

    摘要： PURPOSE:To form an oral intake composition useful as a healthy food for preventing hypertension and alleviating hypertensive tendency, by using inhibitory peptide of angiotensin converting enzyme derived from casein and egg yolk. CONSTITUTION:An oral intake composition containing a peptide inhibiting angiotensin converting enzyme(ACE for short) obtained by decomposing casein with protease and egg yolk. The peptide inhibiting ACE is usually isolated in the form of powder, blended with egg yolk and used as it is or preferably as a composition in any shape or configuration together with a proper nontoxic carrier for oral administration. Egg yolk of egg of chicken, quail, ostrich, etc., sold in the market can be used as the egg yolk. Total content of the inhibitory peptide of ACE and egg yolk is generally about 1-100wt%. and the ratio of the above-mentioned peptide and the egg yolk is generally about 1:10-3:1.