专利检索 ap:("ADIR") AND inv:"PIEERU RUNAARU" 第 1 页

1.

发明专利
失效

公开(公告)号：JP2513989B2

公开(公告)日：1996-07-10

申请号：JP9401294

申请日：1994-03-25

申请人： ADIR

发明人： BERUNAARU PIROTSUTO , PASUKARU DO CHURIO , BERUNAARU MASUREERU , JATSUKU DERARUJU , JAN REPANYOORU , PIEERU RUNAARU

IPC分类号： A61K31/54 , A61P25/00 , A61P25/18 , A61P25/20 , A61P25/24 , A61P25/26 , A61P25/28 , C07D513/04

2.

发明专利
NEW SUBSTITUTED INDOLE, ITS PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING SAID INDOLE 失效

公开(公告)号：JPH072770A

公开(公告)日：1995-01-06

申请号：JP9881394

申请日：1994-05-12

申请人： ADIR

发明人： POORU KOBEERU , BURIJITSUTO JIYAMARU-GURUGOWA , KATORIN KOBEERU , JIYAN GIYUI BIZO ESUPIAARU , PIEERU RUNAARU , JIYARAARU ADAMU

IPC分类号： A61K31/40 , A61K31/403 , A61K31/404 , A61K31/44 , A61K31/4427 , A61K31/443 , A61K31/4433 , A61K31/445 , A61K31/47 , A61P3/00 , A61P9/08 , A61P9/10 , A61P29/00 , C07D209/14 , C07D209/42 , C07D401/04 , C07D401/06 , C07D401/12 , C07D403/12 , C07D405/12 , C07D409/12 , C07D417/12

3.

发明专利
失效

公开(公告)号：JPH05239054A

公开(公告)日：1993-09-17

申请号：JP17442992

申请日：1992-07-01

申请人： ADIR

发明人： JIERAARU GIYUROOMU , KUROODO FUYUJIE , JIYAN KUROODO JIYUSUCHIN SUBUI , JIERAARU ADAMU , PIEERU RUNAARU , DANIERU ANRI KENIYUNAARU

IPC分类号： A61K31/40 , A61K31/42 , A61K31/435 , A61P25/00 , C07D311/58 , C07D335/06 , C07D405/12 , C07D409/12 , C07D413/12 , C07D417/12 , C07D491/056 , C07D498/04

4.

发明专利
MEDICINE COMPOSITION CONTAINING N-(- HEXAHYDROAZEPINYLALKYL) ACETOAMIDE COMPOUND FOR TREATING CHOLINERGIC TRANSMISSION DISTURBANCE 失效

公开(公告)号：JPH04257521A

公开(公告)日：1992-09-11

申请号：JP23161291

申请日：1991-09-11

申请人： ADIR

发明人： MOORISU ISURAERU , IBETSUTO MORO GAUDORII , MATSUKUSU ROTSUBA , JIERAARU ADAMU , PIEERU RUNAARU

IPC分类号： A61K31/34 , A61K31/341 , A61K31/343 , A61K31/38 , A61K31/381 , A61K31/55 , A61P25/18 , A61P25/28 , A61P43/00 , C07D209/18 , C07D233/64 , C07D235/16 , C07D295/12 , C07D307/54 , C07D307/79 , C07D333/24 , C07D333/60

摘要： PURPOSE: To obtain a pharmaceutical composition containing, as an effective ingredient, an N-(1-hexahydroazepinylalkyl)acetamide compound that has a cholinergic transmission effect by strongly stimulating release of acetylcholin. CONSTITUTION: This pharmaceutical composition, which is used for therapeutic treatment of cholinergic transmission disturbance, Alzheimer's disease, aging- related cerebropathies, and myastheniae without side effects, contains a compound of formula I (R is H or an alkyl; (n) is 0-4; R1 and R2 are each an alkyl, alkenyl, cycloalkyl, cycloalkenyl, aralkyl, heteroaryl or heteroaralkyl), its isomer or pharmacologically permissible acid adduct [for example, cyclohexyl N-[3-(1- hexahydroazepinyl)-propyl]-thien-3-ylacetamide, etc.].

5.

发明专利
NEW SUBSTITUTED PIPERAZINES, THEIR PRODUCTION AND MEDICINAL COMPOSITIONS 失效

公开(公告)号：JPH0753548A

公开(公告)日：1995-02-28

申请号：JP20126194

申请日：1994-07-22

申请人： ADIR

发明人： JIYAN JIYATSUKU GOTSUDOFUROWA , AAZUDAN RAMURI , ESUTERA TOUBURU , KUWAN WANGU , PIEERU RUNAARU , BURUNO FUAIFUAA , BEATORISU GARUDEIORA

IPC分类号： A61K31/495 , A61K31/505 , A61P3/08 , A61P3/10 , C07D401/06 , C07D403/04 , C07D403/06 , C07D413/04 , C07D413/06

6.

发明专利
NEW (ARYL(ALKYL)CARBONYL) HETEROCYCLIC COMPOUND 失效

公开(公告)号：JPH072850A

公开(公告)日：1995-01-06

申请号：JP3492494

申请日：1994-03-04

申请人： ADIR

发明人： USUMAN DEIUFU , DANIERU RUSHIYUU , PATORITSUKU DOYUPURIYUU , BEATORISU GARUDEIORA RUMETORU , DANIERU ANRI KENIYAARU , PIEERU RUNAARU , JIERAARU ADAMU

IPC分类号： A61K31/42 , A61K31/423 , A61K31/425 , A61K31/428 , A61K31/445 , A61K31/54 , A61P25/00 , A61P25/18 , A61P25/20 , A61P25/24 , A61P25/26 , A61P43/00 , C07D263/58 , C07D277/68 , C07D413/06 , C07D417/06

7.

发明专利
NEW PYRROROPYRAZINE COMPOUND, ITS PRODUCTION AND PHARMACEUTICAL COMPOSITION CONTAINING IT 失效

公开(公告)号：JPH06340666A

公开(公告)日：1994-12-13

申请号：JP12796394

申请日：1994-05-02

申请人： ADIR

发明人： SHIRUBUEN RORU , JIYAN SHIYARURU RANSURO , ERUBUE PURUNIE , MATSUKUSU ROBA , FUIRITSUPU DERAGURANJIYU , PIEERU RUNAARU , JIERAARU ADAMU

IPC分类号： A61K31/495 , A61K31/505 , A61P1/00 , A61P1/08 , A61P25/00 , A61P25/04 , A61P25/06 , A61P25/18 , A61P25/20 , A61P25/28 , A61P25/30 , A61P43/00 , C07D471/04 , C07D471/14 , C07D487/04 , C07D487/14

8.

发明专利
NEW 3-(HYDROXYBENZYLIDENYL)INDOLIN-2-ONES, THEIR PRODUCTION AND MEDICINAL COMPOSITIONS CONTAINING THEM 失效

公开(公告)号：JPH06179652A

公开(公告)日：1994-06-28

申请号：JP17906493

申请日：1993-07-20

申请人： ADIR

发明人： GIYUIROOMU RU BO , MARI RUNE NURISON , JIYAN FURANSOWA RUNO DOU RA FU , JIYAN GIYUI BIZO ESUPIARU , DANIERU ANRI KENIYAARU , PIEERU RUNAARU , JIERAARU ADAMU

IPC分类号： A61K31/40 , A61K31/403 , A61K31/404 , A61K31/44 , A61K31/4427 , A61P3/00 , A61P7/02 , A61P9/08 , A61P9/10 , A61P11/00 , A61P25/04 , A61P29/00 , A61P37/00 , A61P37/08 , C07D209/30 , C07D209/34 , C07D401/04

摘要： The invention relates to compounds of the formula (I): in which R1, R2, R3, R4, R5 and X are as defined in the description, to their Z and E isomers, to their optical isomers, in the pure form or in a mixed form, and to their addition salts with a pharmaceutically acceptable acid or base. Medicaments.

9.

发明专利
NOVEL HETEROCYCLICALLY SUBSTITUTED ALKYLAMIDE, PREPARATION THEREOF AND MEDICINAL COMPOSI- TION CONTAINING SAME 失效

公开(公告)号：JPH0597828A

公开(公告)日：1993-04-20

申请号：JP6745392

申请日：1992-03-25

申请人： ADIR

发明人： SE YU , IZABERU RUSHIUURU , PATORITSUKU DEPURIYU , DANIERU ANRI KEIGUNAARU , BEATORISU GIYUARUDEIORA , JIERAARU ADAMU , PIEERU RUNAARU

IPC分类号： A61K31/42 , A61K31/423 , A61K31/425 , A61K31/428 , A61K31/445 , A61K31/495 , A61K31/496 , A61K31/535 , A61K31/536 , A61K31/5377 , A61K31/538 , A61K31/54 , A61K31/5415 , A61P1/14 , A61P25/00 , A61P25/04 , A61P25/08 , A61P25/20 , A61P25/24 , A61P25/26 , A61P25/28 , C07D263/58 , C07D265/36 , C07D277/68 , C07D279/16 , C07D413/12 , C07D417/12

10.

发明专利
NOVEL N-BENZOYLPROLINE COMPOUND 失效

公开(公告)号：JPH04283561A

公开(公告)日：1992-10-08

申请号：JP29922891

申请日：1991-11-14

申请人： ADIR

发明人： SHIRUBEIN RAURU , MARII POURU FUOROTSUPU , MATSUKUSU ROTSUBA , MISHIERU BURUAARU , PIEERU RUNAARU , MISHIERU DOUBISAGUE , JIERAARU ADAMU

IPC分类号： A61K31/40 , A61K31/401 , A61P9/00 , A61P9/10 , A61P25/28 , C07D207/08 , C07D207/16 , C07D207/24 , C07D405/06 , C07D491/08