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公开(公告)号：JP2011097925A
公开(公告)日：2011-05-19
申请号：JP2010225025
申请日：2010-10-04
发明人： TAGUCHI HIROYUKI , YOSHIDA HIROSHI , FUSE CHIE , ARINAMI TADAO
IPC分类号： C12N15/09 , A61K31/711 , A61K48/00 , A61P17/00 , C07K14/47 , C07K16/18 , C12Q1/68 , G01N33/15 , G01N33/50 , G01N33/53
CPC分类号： C12Q1/6876 , C12N2501/00 , C12Q1/68 , C12Q2600/148 , G01N33/15 , G01N33/502
摘要： PROBLEM TO BE SOLVED: To provide a genetic polymorphism and a hair shape susceptibility gene that are related to hair shape and a method for determining genetic susceptibility to hair shape in each test subject. SOLUTION: The hair shape susceptibility gene is a gene in the 1q21.3 region (D1S2696-D1S2346) of human chromosome 1 that overlaps a haplotype block comprising a specific base sequence and that is determined by means of linkage disequilibrium analysis of single nucleotide polymorphism (SNP) markers wherein the allele frequency is statistically significantly different between a group that has a non-straight hair trait and a group that has a straight hair trait. The hair shape susceptibility gene is a gene that contains a portion or all of the base sequence of the haplotype block. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译： 待解决的问题：提供与头发形状有关的遗传多态性和毛发易感性基因，以及每个测试对象中确定头发形状的遗传易感性的方法。 解决方案：头发形状敏感性基因是人染色体1的1q21.3区域（D1S2696-D1S2346）中的基因，其与包含特定碱基序列的单元型区块重叠，并且通过单个连锁不平衡分析来确定 核苷酸多态性（SNP）标记，其中在具有非直发性状的群体和具有直发特征的群体之间的等位基因频率在统计学上显着不同。 头发形状敏感性基因是含有单倍型区段的一部分或全部碱基序列的基因。 版权所有（C）2011，JPO＆INPIT
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公开(公告)号：JP2010150294A
公开(公告)日：2010-07-08
申请号：JP2010072334
申请日：2010-03-26
发明人： YOSHIDA HIROSHI , TAGUCHI HIROYUKI
IPC分类号： A61K31/7016 , A61K35/20 , A61K36/00 , A61K36/02 , A61K36/06 , A61K36/42 , A61K38/00 , A61P9/00 , A61P9/10 , A61P9/12 , A61P11/00 , A61P11/06 , A61P13/12 , A61P17/02 , A61P17/06 , A61P17/14 , A61P19/02 , A61P29/00 , A61P31/04 , A61P43/00
摘要： PROBLEM TO BE SOLVED: To provide an S100A8 expression regulator useful for prevention or treatment of various symptoms and diseases caused in relation to over-expression or lowered expression of S100A8, regulating S100A8 in vivo. SOLUTION: The S100A8 expression regulator comprises one or more selected from the group consisting of a plant, yeast, whey, silk hydrolyzate, spirulina, their extracts and trehalose, as an active ingredient. COPYRIGHT: (C)2010,JPO&INPIT
摘要翻译： 要解决的问题：提供一种S100A8表达调节剂，用于预防或治疗与S100A8的过表达或降低的表达相关的各种症状和疾病，在体内调节S100A8。 解决方案：S100A8表达调节剂包含选自植物，酵母，乳清，丝状水解产物，螺旋藻，其提取物和海藻糖的一种或多种作为活性成分。 版权所有（C）2010，JPO＆INPIT
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公开(公告)号：JP2008105995A
公开(公告)日：2008-05-08
申请号：JP2006290029
申请日：2006-10-25
IPC分类号： A61K36/00 , A61K8/97 , A61K36/18 , A61P17/00 , A61P17/02 , A61P17/06 , A61P17/14 , A61P31/00 , A61Q7/00 , A61Q19/00
摘要： PROBLEM TO BE SOLVED: To provide a skin preparation for external use accelerating the expression of S100A8 (synonym: calgranulin A or MRP-8). SOLUTION: This skin preparation for external use comprises at least one selected from a plant belonging to Adjantaceae or Liliaceae as an active component. As the plant belonging to the Adjantaceae, (Cheilanthes albomarginata L.B.) and as the plant belonging to the Liliaceae, (Diuranthera minor (C.H. Wright) Hemsl.) can be cited. COPYRIGHT: (C)2008,JPO&INPIT
摘要翻译： 要解决的问题：提供加速S100A8（同义词：钙粒蛋白A或MRP-8）的表达的外用皮肤制剂。 解决方案：该外用皮肤制剂包含至少一种选自属于金盏科或百合科的植物作为活性成分。 作为属于槐科（Cheilanthes albomarginata L.B.）的植物和属于百合科的植物（Diuranthera minor（C.H.Weight）Hemsl。））。 版权所有（C）2008，JPO＆INPIT
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公开(公告)号：JP2011097926A
公开(公告)日：2011-05-19
申请号：JP2010225186
申请日：2010-10-04
发明人： TAGUCHI HIROYUKI , YOSHIDA HIROSHI , FUSE CHIE , ARINAMI TADAO
CPC分类号： C12N15/09 , C12Q1/68 , G01N33/15 , G01N33/50 , G01N33/53 , C12Q1/6897 , C12Q2600/148
摘要： PROBLEM TO BE SOLVED: To provide a gene polymorphism related to hair shapes, a susceptibility gene for hair shapes, and a method for assessing the genetic susceptibility of individual subjects to hair shapes. SOLUTION: The susceptibility gene for hair shapes is a gene on the 11q12.2-11q13.2 regions (D11S4191 and D11S987) of the human chromosome 11 in which an allele frequency is determined by the linkage disequilibrium analysis of a single nucleotide polymorphism (SNP) marker with differing statistical significance between a group with unruly hair characteristics and a group with non-unruly hair characteristics, and which overlaps with a haplotype block comprising a specific base sequence and is a gene comprising either a portion or all of the base sequence in the haplotype block. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译： 要解决的问题：提供与头发形状有关的基因多态性，毛发形状的易感基因，以及用于评估个体受试者对毛发形状的遗传易感性的方法。 解决方案：头发形状的易感性基因是人染色体11的11q12.2-11q13.2区域（D11S4191和D11S987）上的基因，其中等位基因频率通过单核苷酸的连锁不平衡分析来确定 多态性（SNP）标记，具有不统一的头发特征的组与具有非不规则毛发特征的组之间具有不同的统计学意义，并且与包含特异性碱基序列的单元型块重叠，并且是包含部分或全部 碱基序列。 版权所有（C）2011，JPO＆INPIT
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公开(公告)号：JP2008105991A
公开(公告)日：2008-05-08
申请号：JP2006289631
申请日：2006-10-25
IPC分类号： A61K36/18 , A61K8/97 , A61K36/00 , A61K36/48 , A61K36/60 , A61P17/00 , A61P17/02 , A61P17/06 , A61P17/14 , A61P31/04 , A61P43/00 , A61Q7/00
摘要： PROBLEM TO BE SOLVED: To provide an S100A8 accelerator for accelerating the expression of S100A8.
SOLUTION: This S100A8 expression accelerator comprises ≥1 kind selected from plants belonging to Moraceae, Fabaceae, Thymeleaceae, Balsaminaceae or Typhaceae as active ingredients. As the plant belonging to the Moraceae, (Artocarpus lakoocha Roxb.), as the plant belonging to the Farbaceae, (Albizia lebbeck (Linn.) Benth), as the plant belonging to the Thymeleaceae, (Alocasia odora (Roxb.) C Koch), as the plant belonging to the Balsaminaceae, (Impatiens balsamuna L) and as the plant belonging to the Typhaceae, (Typha latifolia L., T. angustifolia L.) can be cited.
COPYRIGHT: (C)2008,JPO&INPIT摘要翻译： 要解决的问题：提供用于加速S100A8表达的S100A8加速器。 解决方案：该S100A8表达促进剂含有选自属于禾本科，豆科，百日咳科，竹ace科或Typ科植物的植物中的≥1种作为活性成分。 作为属于禾本科（Artocarpus lakoocha Roxb。）的植物，作为属于禾本科的植物（合欢树ck（Linn。）Benth），作为属于百里香科的植物（Alocasia odora（Roxb。）C Koch ），作为属于木瓜科植物（Impatiens balsamuna L）的植物和属于Typ科的植物（Typha latifolia L.，T. angustifolia L.）。 版权所有（C）2008，JPO＆INPIT
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公开(公告)号：JP2006045168A
公开(公告)日：2006-02-16
申请号：JP2004232063
申请日：2004-08-09
发明人： YOSHIDA HIROSHI , TAGUCHI HIROYUKI
IPC分类号： A61K36/18 , A61K8/00 , A61K8/96 , A61K31/7016 , A61K35/20 , A61K36/06 , A61K36/07 , A61K36/25 , A61K36/28 , A61K36/42 , A61K36/48 , A61K36/53 , A61K36/71 , A61K36/73 , A61K36/75 , A61K36/81 , A61K36/899 , A61K38/00 , A61P9/08 , A61P9/10 , A61P9/12 , A61P11/00 , A61P11/06 , A61P11/08 , A61P13/12 , A61P17/00 , A61P17/02 , A61P17/06 , A61P17/14 , A61P19/02 , A61P29/00 , A61P31/04 , A61P43/00 , A61Q19/00
摘要： PROBLEM TO BE SOLVED: To provide an S100A8 expression regulator useful for prophylaxis or therapy of various kinds of symptoms or diseases caused in relation to hyperexpression or hypoexpression of the S100A8 and regulating the expression of the S100A8 in vivo. SOLUTION: The S100A8 expression regulator comprises one or more selected from the group consisting of a plant, a yeast, whey, a silk hydrolyzate, an alga of the genus Spirulina and an extract thereof and trehalose as an active ingredient. COPYRIGHT: (C)2006,JPO&NCIPI
摘要翻译： 要解决的问题：提供一种S100A8表达调节剂，用于预防或治疗与S100A8的过度表达或低表达相关的各种症状或疾病，并调节S100A8在体内的表达。 解决方案：S100A8表达调节剂包括选自植物，酵母，乳清，丝状水解产物，螺旋藻属的藻类及其提取物和海藻糖作为活性成分的一种或多种。 版权所有（C）2006，JPO＆NCIPI
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公开(公告)号：JP2013010796A
公开(公告)日：2013-01-17
申请号：JP2012227849
申请日：2012-10-15
发明人： YOSHIDA HIROSHI , TAGUCHI HIROYUKI
摘要： PROBLEM TO BE SOLVED: To provide a control agent for an expression of S100A8 capable of controlling the expression of S100A8 in vivo, which is useful for prevention or treatment of various symptoms and diseases caused by the relation to an overexpression and a decreased expression of S100A8.SOLUTION: Provided is an S100A8 expression promoter having as an active ingredient one or more chosen from the group consisting of pumpkin, lime, cohosh, and extracts therefrom.
摘要翻译： 待解决的问题：提供能够控制体内S100A8表达的S100A8的表达控制剂，其可用于预防或治疗由与过表达的关系引起的各种症状和疾病 S100A8的表达。 解决方案：提供具有作为活性成分的选自南瓜，石灰，焦磷酸盐及其提取物中的一种或多种的S100A8表达启动子。 版权所有（C）2013，JPO＆INPIT
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公开(公告)号：JP2011097927A
公开(公告)日：2011-05-19
申请号：JP2010225225
申请日：2010-10-04
发明人： TAGUCHI HIROYUKI , YOSHIDA HIROSHI , FUSE CHIE , ARINAMI TADAO
CPC分类号： C12Q1/6827 , C12Q1/6876 , C12Q1/6883 , C12Q2600/124 , C12Q2600/172 , G01N33/68
摘要： PROBLEM TO BE SOLVED: To provide a gene polymorphism related to hair shapes, a susceptibility gene for hair shapes, and a method for assessing the genetic susceptibility of individual subjects to hair shapes. SOLUTION: The susceptibility gene for hair shapes is a gene on the 1q32.1-1q32.2 regions (D1S249-D1S2891) of the human chromosome 1 in which an allele frequency is determined by the linkage disequilibrium analysis of a single nucleotide polymorphism (SNP) marker with differing statistical significance between a group with unruly hair characteristics and a group with non-unruly hair characteristics, and which overlaps with a haplotype block comprising a specific base sequence and is a gene that comprises either a portion or all of the base sequence in the haplotype block. COPYRIGHT: (C)2011,JPO&INPIT
摘要翻译： 要解决的问题：提供与头发形状有关的基因多态性，毛发形状的易感基因，以及用于评估个体受试者对毛发形状的遗传易感性的方法。 解决方案：毛发形状的易感性基因是人染色体1的1q32.1-1q32.2区域（D1S249-D1S2891）上的基因，其中等位基因频率通过单核苷酸的连锁不平衡分析来确定 具有不规则头发特征的组与具有非不规则头发特征的组之间具有不同统计学显着性的多态性（SNP）标记，并且与包含特异性碱基序列的单倍型块重叠并且是包含部分或全部 单倍型区段中的碱基序列。 版权所有（C）2011，JPO＆INPIT
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公开(公告)号：JP2006159713A
公开(公告)日：2006-06-22
申请号：JP2004356090
申请日：2004-12-08
发明人： ITAYA YUKIO , YOSHIDA HIROSHI
摘要： PROBLEM TO BE SOLVED: To provide an elastic mold which can demold a molding easily and is easy of handling.
SOLUTION: In the elastic mold 1 having a body mold part 2 which is filled with a filling 5 and solidifies it, a frame 3 for fixing the body mold part to a through-hole 13 formed in a fixed plate 12 in a vacuum device 6, and a joint 8 for connecting the body mold part and the frame continuously, the wall of the connection part is thinner than the wall of the body mold part.
COPYRIGHT: (C)2006,JPO&NCIPI摘要翻译： 要解决的问题：提供一种能够容易地使模制脱模并易于处理的弹性模具。 解决方案：在具有填充有填充物5并使其固化的主体模具部分2的弹性模具1中，用于将主体模具部分固定到形成在固定板12中的通孔13的框架3 真空装置6和用于连续地连接主体模具部分和框架的接头8，连接部分的壁比主体模具部分的壁薄。 版权所有（C）2006，JPO＆NCIPI
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公开(公告)号：JP2019094326A
公开(公告)日：2019-06-20
申请号：JP2018216797
申请日：2018-11-19
申请人： KAO CORP
发明人： YOSHIDA HIROSHI , SAKAI YUTA , HIRAYAMA MASUTARO , KOMABA SHINGO
摘要： 【課題】シャンプーなどの日常のヘアケア行動により簡単に白髪を目立たなくすることができ、高い染毛性を発揮し得る毛髪化粧料を提供する。【解決手段】次の成分(A)〜(E)を含有し、成分(E)に対する成分(A)の質量比(A)/(E)が、0.05以上2未満である毛髪化粧料。(A)下記一般式(1)で表される化合物又はその塩〔式中、破線はπ結合の存在又は不存在を示す。R1は水酸基又はアセトキシ基を示す。R2は水素原子、又は−COOR(Rは水素原子、メチル基又はエチル基)を示す。R3は水素原子、アセチル基、メチル基又はエチル基を示す。〕、(B)アルカリ剤、(C)緩衝剤、(D)アニオン性界面活性剤、(E)カチオン電荷密度が0.01meq/g以上4.8meq/g以下のカチオン性ポリマー。【選択図】なし
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