公开(公告)号：JP2012115726A

公开(公告)日：2012-06-21

申请号：JP2010265555

申请日：2010-11-29

Applicant: Takasago Internatl Corp ,  高砂香料工業株式会社

Inventor： YAMADA SHINYA ,  MAEDA HIRONORI ,  HORI YASUSHI

IPC: B01J31/28 ,  C07B53/00 ,  C07B61/00 ,  C07C45/62 ,  C07C47/21

CPC classification number: B01J31/04 ,  B01J21/12 ,  B01J23/40 ,  B01J23/44 ,  B01J23/74 ,  B01J23/755 ,  B01J27/053 ,  B01J29/068 ,  B01J29/072 ,  B01J31/062 ,  B01J31/1616 ,  B01J31/2217 ,  B01J31/26 ,  B01J2231/645 ,  B01J2531/0275 ,  B01J2531/821 ,  B01J2531/822 ,  B01J2531/824 ,  B01J2531/827 ,  B01J2531/828 ,  B01J2531/847 ,  C07B53/00 ,  C07B2200/07 ,  C07C45/62 ,  Y02P20/588 ,  C07C47/21

Abstract: PROBLEM TO BE SOLVED: To provide a catalyst for producing optically-active aldehydes or ketones being optically-active carbonyl compounds by selectively asymmetrically hydrogenating α, β-unsaturated carbonyl compounds, particularly a catalyst insoluble in a reaction mixture for obtaining an optically-active citronellal useful as a perfume by selectively asymmetrically hydrogenating citral, geranial or neral; and also to provide a method for producing corresponding optically-active carbonyl compounds.SOLUTION: The invention relates to a catalyst for asymmetrically hydrogenating α, β-unsaturated carbonyl compounds, which contains: the powder of at least one metal selected from group 8-10 metals in the periodic table, or a metal-supported material in which at least one metal selected from group 8-10 metals is supported by a carrier; an optically-active peptide compound; and an acid, and also relates to a method for producing optically-active carbonyl compounds using the catalyst.

Abstract translation: 要解决的问题：提供一种用于通过选择性不对称氢化α，β-不饱和羰基化合物，特别是不溶于反应混合物中的催化剂以获得光学活性的羰基化合物来提供用于制备光学活性的醛或酮的催化剂， 活性香茅醛通过选择性不对称氢化柠檬醛，香叶酸或香草来用作香料; 并且还提供了制备相应的光学活性羰基化合物的方法。 解决方案：本发明涉及用于不对称氢化α，β-不饱和羰基化合物的催化剂，其包含：选自周期表中第8-10族金属中的至少一种金属的粉末或金属负载材料 其中选自第8-10族金属中的至少一种金属由载体支撑; 光学活性肽化合物; 和酸，还涉及使用该催化剂制备光学活性羰基化合物的方法。 版权所有（C）2012，JPO＆INPIT

公开(公告)号：JP2009185033A

公开(公告)日：2009-08-20

申请号：JP2009055544

申请日：2009-03-09

Applicant: Takasago Internatl Corp ,  高砂香料工業株式会社

Inventor： MAJIMA KAZUYUKI ,  OSHIMA TAKASHI ,  IWASAKI TAKANORI ,  MAEDA HIRONORI ,  ISHIDA MASAYA

IPC: C07F3/06 ,  C07B61/00 ,  C07D263/10 ,  C07D263/12 ,  C07D263/14 ,  C07D263/52 ,  C07D413/06

CPC classification number: C07D263/12 ,  B01J31/2226 ,  B01J2531/26 ,  C07C53/18 ,  C07C231/02 ,  C07C253/30 ,  C07D263/10 ,  C07D263/14 ,  C07D263/52 ,  C07D413/06 ,  C07F3/003 ,  C07F7/1892 ,  C07F9/5022 ,  C07K1/088 ,  C07K1/10

Abstract: PROBLEM TO BE SOLVED: To provide a new method for producing an azoline compound from an aminochalcogenide, and a carboxylic acid, a carboxylic acid ester or nitrile, in high selectivity and efficiency. SOLUTION: A method for producing an oxazoline compound expressed by a reaction scheme of formula (1) in the presence of a compound containing group 12 metal element of the periodic table is disclosed as an example. As a raw material ester compound, methyl benzoate is cited as an example. The azoline compound expressed by formula (3) (wherein R 1 , R 3 to R 6 represent each an alkoxy group, an amino group or the like; Z 1 represents each O, S or Se) can be obtained by selecting an aminochalcogenide reacting with the ester compound. COPYRIGHT: (C)2009,JPO&INPIT

Abstract translation: 待解决的问题：提供一种以高选择性和高效率从氨基硫属化合物和羧酸，羧酸酯或腈制备唑啉化合物的新方法。 解决方案：作为实例，公开了在含有元素周期表第12族金属元素的化合物的存在下由式（1）的反应式表示的恶唑啉化合物的制造方法。 作为原料酯化合物，以苯甲酸甲酯为例。 由式（3）表示的唑啉化合物（其中R 1，R 2，R 3，R 3，R 6，R 6和R 6表示各自为烷氧基，氨基或 可以通过选择与酯化合物反应的氨基硫属化合物来获得Z 1 表示每个O，S或Se）。 版权所有（C）2009，JPO＆INPIT

公开(公告)号：JP2012131785A

公开(公告)日：2012-07-12

申请号：JP2011262574

申请日：2011-11-30

Applicant: Takasago Internatl Corp ,  高砂香料工業株式会社

Inventor： MAEDA HIRONORI ,  ITO HISANORI ,  YAMADA SHINYA ,  HORI YASUSHI

IPC: C07C29/156 ,  B01J25/02 ,  B01J31/22 ,  B01J31/28 ,  C07B53/00 ,  C07B57/00 ,  C07B61/00 ,  C07C35/12

CPC classification number: C07C29/132 ,  B01J21/18 ,  B01J23/44 ,  C07B53/00 ,  C07B2200/07 ,  C07C29/17 ,  C07C29/56 ,  C07C2601/14 ,  C07C35/12 ,  C07C35/17

Abstract: PROBLEM TO BE SOLVED: To provide a method for producing optically-active menthol, which is composed of a few steps that are all catalytic reaction steps, therefore producing little environment-polluting waste, and can achieve a reduction in the manufacturing cost.SOLUTION: The method for producing optically-active menthol includes steps of: (A-1) subjecting at least one of geranial and neral to asymmetric hydrogenation to obtain optically active citronellal; (B-1) subjecting the optically active citronellal to ring-closing reaction with an acid catalyst to obtain optically active isopulegol; and (C-1) hydrogenating the optically active isopulegol to obtain optically active menthol.

Abstract translation: 要解决的问题：提供一种由全部催化反应步骤的几个步骤组成的光学活性薄荷醇的方法，因此几乎不产生环境污染的废物，并且可以实现制造成本的降低 。 解决方案：用于制备光学活性薄荷醇的方法包括以下步骤：（A-1）将至少一种龙涎香和不饱和氢化物进行不对称氢化以获得光学活性的香茅醛; （B-1）使光学活性香茅醛与酸催化剂进行闭环反应，得到光学活性的异胡前药; 和（C-1）氢化旋光异黄酮获得光学活性薄荷醇。 版权所有（C）2012，JPO＆INPIT