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273 条记录 (耗时 0.028 秒)

    Use of PEO-PBO block copolymers in ophthalmic compositions
    1.
    发明授权
    Use of PEO-PBO block copolymers in ophthalmic compositions 有权

    公开(公告)号：US10584307B2

    公开(公告)日：2020-03-10

    申请号：US15398761

    申请日：2017-01-05

    申请人： ALCON RESEARCH, LTD.

    发明人： Howard Allen Ketelson ,  Nathaniel D. McQueen

    IPC分类号： C11D3/00 ,  C11D1/00 ,  A45C11/00 ,  A61F2/16 ,  B65D81/22 ,  C11D3/37

    摘要： The use of poly(oxyethylene)-poly(oxybutylene) block copolymers in pharmaceutical compositions useful for modifying the surfaces of contact lenses and other medical devices is disclosed. The present invention is based in-part on a discovery that this class of compounds is particularly efficient in wetting hydrophobic surfaces, such as the surfaces of silicone hydrogel contact lenses and other types of ophthalmic lenses. Such compounds are also useful for cleaning purposes. The use of the compounds as surfactants in various types of compositions for treating contact lenses therefore represents a preferred embodiment of the present invention.

    Cyclic aperture flow regulator system
    2.
    发明授权
    Cyclic aperture flow regulator system 有权

    公开(公告)号：US10470926B2

    公开(公告)日：2019-11-12

    申请号：US14559878

    申请日：2014-12-03

    申请人： Alcon Research, Ltd.

    发明人： Jaime Zacharias

    IPC分类号： A61F9/007 ,  A61M1/00

    摘要： A cyclic aperture flow regulator system has an adjustable fluid aperture in a fluid path connecting the aspiration port of a surgical probe with a vacuum source. The cross-sectional area of the fluid aperture can be modified by an actuator. The actuator is controlled to modify the cross-sectional area of the adjustable fluid aperture in cycles. During each cycle, the fluid aperture cross-sectional area is substantially reduced or closed. The cycles occur at a rate fast enough to produce a substantially steady flow, with minimum flow ripple and pressure ripple.

    OPHTHALMIC EMULSION
    3.
    发明申请
    OPHTHALMIC EMULSION 审中-公开

    公开(公告)号：US20190254971A1

    公开(公告)日：2019-08-22

    申请号：US16405180

    申请日：2019-05-07

    申请人： ALCON RESEARCH, LTD.

    发明人： Howard Allen Ketelson ,  David L. Meadows

    IPC分类号： A61K9/107 ,  B01F17/00 ,  A61K9/00

    摘要： The present invention is directed to an ophthalmic emulsion. The emulsion has a unique combination of ingredients that promotes the stability of small oil droplets within the emulsion. The emulsion also includes a mucoadhesive polymer that aid in delivering a lipid to the ocular surface.

    Selectively moveable valve elements for aspiration and irrigation circuits
    4.
    发明授权
    Selectively moveable valve elements for aspiration and irrigation circuits 有权

    公开(公告)号：US10314741B2

    公开(公告)日：2019-06-11

    申请号：US15334662

    申请日：2016-10-26

    申请人： Alcon Research, Ltd.

    发明人： Gary P. Sorensen ,  Michael D. Morgan

    IPC分类号： A61M1/00 ,  A61F9/007 ,  A61M3/02

    摘要： Various arrangements of fluidics systems are disclosed. In one arrangement, an aspiration circuit for a fluidics system is disclosed that selectively controls aspiration. The aspiration circuit comprises an aspiration line operatively connected to a surgical instrument, an aspiration exhaust line operatively connected to a waste receptacle; an aspiration vent line connected at a first end to the aspiration line; and a selectively variable vent valve operatively connected to the aspiration vent line. The variable vent valve may be selectively moved to vary aspiration pressure within the aspiration line. Other fluidics systems are disclosed that include a selectively positionable irrigation valve that may also be incorporated into a fluidics system that includes a variable vent valve.

    Grin fiber multi-spot laser probe
    5.
    发明授权
    Grin fiber multi-spot laser probe 有权

    公开(公告)号：US10245181B2

    公开(公告)日：2019-04-02

    申请号：US13723600

    申请日：2012-12-21

    申请人： Alcon Research, Ltd.

    发明人： Chenguang Diao ,  Ronald T. Smith

    IPC分类号： A61F9/008

    摘要： A surgical probe includes a cannula assembly, having a graded index (GRIN) fiber that is configured to receive a multi-spot light beam at a proximal end and to emit the multi-spot light beam at a distal end; an adapter, having a distal end, configured to receive the cannula assembly, with the proximal end of the GRIN fiber, a proximal end, configured to couple to a light guide via a connector and to receive a light delivered by the light guide from a laser source to the adapter, and an interface, configured to couple the light delivered by the light guide to the proximal end of the GRIN fiber; wherein a length of the GRIN fiber is sufficiently long that the interface is outside a patient's eye during a photocoagulation procedure.

    Cassette clamp mechanism
    10.
    发明授权
    Cassette clamp mechanism 有权

    公开(公告)号：US09713660B2

    公开(公告)日：2017-07-25

    申请号：US14076418

    申请日：2013-11-11

    申请人： Alcon Research, Ltd.

    发明人： Vincent A. Baxter ,  Daniel J. Wilson

    IPC分类号： A61M1/00 ,  A61F9/007 ,  F04B53/16

    CPC分类号： A61M1/0058 ,  A61F9/00736 ,  A61F9/00745 ,  A61M2205/121 ,  A61M2209/082 ,  A61M2209/084 ,  A61M2210/0612 ,  F04B53/16

    摘要： A surgical cassette clamping system includes a mounting plate having a first side and a second side. A bracket system may be disposed adjacent the first side of the mounting plate. A clamp motor may be disposed adjacent the mounting plate and fixed relative to the mounting plate. The clamp motor may be operably connected to the bracket system to displace the bracket system relative to the mounting plate. The system may also include a plurality of pivot arms pivotably connected to the bracket system and extending adjacent the second side of the mounting plate. An engagement portion may be attached to each of the plurality of pivot arms that cooperatively engages the second side of the mounting plate, the engagement portion being operable to pivot the pivot arms when the bracket system moves relative to the mounting plate.