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公开(公告)号:US12226266B2
公开(公告)日:2025-02-18
申请号:US18138600
申请日:2023-04-24
Applicant: ENDOMAGNETICS LTD
Inventor: Tiziano Agostinelli , Kevin Lorimer , Quentin John Harmer
Abstract: A detection system and method uses an implantable magnetic marker comprising at least one piece of a large Barkhausen jump material (LBJ). The marker is deployed to mark a tissue site in the body for subsequent surgery, and the magnetic detection system includes a handheld probe to excite the marker below the switching field for bistable switching of the marker causing a harmonic response to be generated in a sub-bistable mode that allows the marker to be detected and localised. The marker implanted may also be shorter than the critical length required to initiate bistable switching of the LBJ material.
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公开(公告)号:US12207915B2
公开(公告)日:2025-01-28
申请号:US18024448
申请日:2021-09-06
Applicant: ENDOMAGNETICS LTD
Inventor: Quentin John Harmer , Tiziano Agostinelli
Abstract: Systems and Methods for Detecting Magnetic Markers for Surgical Guidance Methods and systems for detecting a magnetic marker for guiding a surgeon to a region of interest during a surgical procedure comprising generating a driving magnetic field having a cyclic pattern comprising two or more successive periods of time, the driving magnetic field having a substantially constant, non-zero amplitude during each of the successive periods of time, and the amplitude of the driving magnetic field during at least one of the periods of time being different from the amplitude of the driving magnetic field during at least one other of the periods of time; detecting a response magnetic field; selecting at least one signal from a plurality of sensed signals, each of which corresponds to the response magnetic field detected during a respective one of the successive periods of time of each cycle; determining a detection signal corresponding to the magnetic marker using the at least one selected signal; and generating an output signal (e.g. an audio or display signal) based on a strength of the detection signal.
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公开(公告)号:US20230329578A1
公开(公告)日:2023-10-19
申请号:US18013839
申请日:2021-07-08
Applicant: ENDOMAGNETICS LTD
Inventor: Quentin John Harmer , Kevin Lorimer , Matthew James Stephens
CPC classification number: A61B5/064 , A61B34/20 , A61B2018/00297
Abstract: A method for detecting a marker in a body, comprising receiving an input signal from a probe, where the input signal is generated by a probe in response to detecting a marker signal from the marker; determining a marker proximity value based on the input signal, the marker proximity value corresponds to a distance between the probe and the marker; generating a feedback signal for output by a user interface device based on the marker proximity value, and outputting feedback signal, wherein range of the marker proximity value is divided into predetermined distance bands; and wherein at least one parameter of the feedback signal, or a rate of change of the at least one parameter of the feedback signal in relation to marker proximity value, is varied discontinuously at a boundary between at least two adjacent bands. The feedback signal may be an audio signal and/or a haptic signal.
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公开(公告)号:US20230320811A1
公开(公告)日:2023-10-12
申请号:US17988146
申请日:2022-11-16
Applicant: ENDOMAGNETICS LTD
Inventor: Eric Mayes , Quentin John Harmer , Kevin Lorimer , Quentin Andrew Pankhurst
CPC classification number: A61B90/39 , A61B5/05 , A61B5/4312 , A61B2090/3954 , A61B2090/3987 , A61B2090/3908 , A61B2090/3995 , A61B2090/3966 , A61B2017/00862
Abstract: A magnetic marker for marking a site in tissue in the body. In one embodiment, the marker comprises a magnetic metallic glass. In another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 9. In yet another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 6. In yet another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 3.
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公开(公告)号:US11504207B2
公开(公告)日:2022-11-22
申请号:US16688318
申请日:2019-11-19
Applicant: ENDOMAGNETICS LTD
Inventor: Eric Mayes , Quentin John Harmer , Kevin Lorimer , Quentin Andrew Pankhurst
Abstract: A magnetic marker for marking a site in tissue in the body. In one embodiment, the marker comprises a magnetic metallic glass. In another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 9. In yet another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 6. In yet another embodiment, the marker is in a non-spherical configuration having an anisotropy ratio less than 3.
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公开(公告)号:USD935028S1
公开(公告)日:2021-11-02
申请号:US29725179
申请日:2020-02-23
Applicant: Endomagnetics LTD
Designer: Quentin Harmer , Kevin Lorimer
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公开(公告)号:USD934428S1
公开(公告)日:2021-10-26
申请号:US29723733
申请日:2020-02-10
Applicant: Endomagnetics LTD
Designer: Quentin Harmer
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公开(公告)号:US20190029560A1
公开(公告)日:2019-01-31
申请号:US15867165
申请日:2018-01-10
Applicant: Endomagnetics Ltd.
Inventor: Quentin John Harmer , Eric Mayes , Quentin Andrew Pankhurst , Andrew Shawcross
IPC: A61B5/06
Abstract: A method and apparatus for preparing tissue of interest in a patient for possible excision by surgery. In one embodiment, the method comprises the steps of: removing a biopsy sample from the tissue of interest; placing a magnetic marker at the biopsy site; performing a pathology analysis of the biopsy sample; and if the pathology analysis indicates that the tissue of interest should be removed, locating the tissue for surgery using a magnetic detection probe. In one embodiment, the marker comprises magnetic nanoparticles in a bioabsorbable matrix. A system for preparing tissue of interest in a patient for possible excision by surgery. In one embodiment, the system includes a magnetic marker and magnetic detection probe system.
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公开(公告)号:US20140018663A1
公开(公告)日:2014-01-16
申请号:US13792803
申请日:2013-03-11
Applicant: Endomagnetics Ltd.
Inventor: Quentin John Harmer , Eric Mayes , Quentin Andrew Pankhurst , Andrew Shawcross
CPC classification number: A61B5/062 , A61B5/06 , A61B5/4312 , A61B10/02 , A61B90/39 , A61B2090/3908 , A61B2090/3954
Abstract: A method and apparatus for preparing tissue of interest in a patient for possible excision by surgery. In one embodiment, the method comprises the steps of: removing a biopsy sample from the tissue of interest; placing a magnetic marker at the biopsy site; performing a pathology analysis of the biopsy sample; and if the pathology analysis indicates that the tissue of interest should be removed, locating the tissue for surgery using a magnetic detection probe. In one embodiment, the marker comprises magnetic nanoparticles in a bioabsorbable matrix. A system for preparing tissue of interest in a patient for possible excision by surgery. In one embodiment, the system includes a magnetic marker and magnetic detection probe system.
Abstract translation: 一种用于通过手术切除患者的感兴趣的组织的方法和装置。 在一个实施方案中,该方法包括以下步骤:从感兴趣的组织中去除活组织检查样品; 在活检部位放置磁性标记物; 进行活检样本的病理分析; 并且如果病理分析指示应该去除感兴趣的组织,则使用磁性检测探针定位用于手术的组织。 在一个实施方案中,标记物包含生物可吸收的基质中的磁性纳米颗粒。 一种用于在患者中制备感兴趣的组织以通过手术切除切除的系统。 在一个实施例中,系统包括磁标记和磁检测探针系统。
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