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    Systems and methods for detecting magnetic markers for surgical guidance
    2.
    发明授权
    Systems and methods for detecting magnetic markers for surgical guidance 有权

    公开(公告)号：US12207915B2

    公开(公告)日：2025-01-28

    申请号：US18024448

    申请日：2021-09-06

    Applicant: ENDOMAGNETICS LTD

    Inventor： Quentin John Harmer ,  Tiziano Agostinelli

    IPC: A61B5/06 ,  A61B6/12 ,  A61B34/20 ,  A61B90/00

    Abstract: Systems and Methods for Detecting Magnetic Markers for Surgical Guidance Methods and systems for detecting a magnetic marker for guiding a surgeon to a region of interest during a surgical procedure comprising generating a driving magnetic field having a cyclic pattern comprising two or more successive periods of time, the driving magnetic field having a substantially constant, non-zero amplitude during each of the successive periods of time, and the amplitude of the driving magnetic field during at least one of the periods of time being different from the amplitude of the driving magnetic field during at least one other of the periods of time; detecting a response magnetic field; selecting at least one signal from a plurality of sensed signals, each of which corresponds to the response magnetic field detected during a respective one of the successive periods of time of each cycle; determining a detection signal corresponding to the magnetic marker using the at least one selected signal; and generating an output signal (e.g. an audio or display signal) based on a strength of the detection signal.

    Multicore Magnetic Particles
    4.
    发明申请
    Multicore Magnetic Particles 审中-公开
    多核磁性颗粒

    公开(公告)号：US20160354495A1

    公开(公告)日：2016-12-08

    申请号：US15171383

    申请日：2016-06-02

    Applicant: ENDOMAGNETICS LTD

    Inventor： Quentin John Harmer ,  Eric Mayes

    IPC: A61K49/18 ,  A61K41/00 ,  A61K49/06

    CPC classification number: A61K49/1863 ,  A61K41/0052 ,  A61K47/6939 ,  B82Y5/00

    Abstract: A multicore magnetic particle. In one embodiment, the magnetic particle includes a plurality of superparmagnetic cores embedded in a non-magnetic matrix. In another embodiment, the effective anisotropy energy barrier of the particle is larger than the sum of the anisotropy energy barriers of the individual superparamagnetic cores. In yet another embodiment, the superparamagnetic cores are close enough to interact magnetically by exchange coupling and dipole interaction. In still yet another embodiment, the specific loss power of the magnetic particle is greater than the specific loss power of an equivalent mass of individual superparamagnetic cores.

    Abstract translation: 多核磁性颗粒。 在一个实施例中，磁性粒子包括嵌入非磁性矩阵中的多个超磁性核心。 在另一个实施方案中，颗粒的有效各向异性能势垒大于各个超顺磁核的各向异性能量势垒的总和。 在另一个实施例中，超顺磁核足够接近以通过交换耦合和偶极相互作用磁化地相互作用。 在另一个实施例中，磁性颗粒的比损耗功率大于单个超顺磁芯的等效质量的比损耗功率。

    SYSTEMS AND METHODS FOR DETECTING MARKERS FOR SURGICAL GUIDANCE
    7.
    发明公开
    SYSTEMS AND METHODS FOR DETECTING MARKERS FOR SURGICAL GUIDANCE 审中-公开

    公开(公告)号：US20230329578A1

    公开(公告)日：2023-10-19

    申请号：US18013839

    申请日：2021-07-08

    Applicant: ENDOMAGNETICS LTD

    Inventor： Quentin John Harmer ,  Kevin Lorimer ,  Matthew James Stephens

    IPC: A61B5/06 ,  A61B34/20

    CPC classification number: A61B5/064 ,  A61B34/20 ,  A61B2018/00297

    Abstract: A method for detecting a marker in a body, comprising receiving an input signal from a probe, where the input signal is generated by a probe in response to detecting a marker signal from the marker; determining a marker proximity value based on the input signal, the marker proximity value corresponds to a distance between the probe and the marker; generating a feedback signal for output by a user interface device based on the marker proximity value, and outputting feedback signal, wherein range of the marker proximity value is divided into predetermined distance bands; and wherein at least one parameter of the feedback signal, or a rate of change of the at least one parameter of the feedback signal in relation to marker proximity value, is varied discontinuously at a boundary between at least two adjacent bands. The feedback signal may be an audio signal and/or a haptic signal.

    Magnetic Marker for Surgical Localization
    10.
    发明申请
    Magnetic Marker for Surgical Localization 审中-公开

    公开(公告)号：US20190029560A1

    公开(公告)日：2019-01-31

    申请号：US15867165

    申请日：2018-01-10

    Applicant: Endomagnetics Ltd.

    Inventor： Quentin John Harmer ,  Eric Mayes ,  Quentin Andrew Pankhurst ,  Andrew Shawcross

    IPC: A61B5/06

    Abstract: A method and apparatus for preparing tissue of interest in a patient for possible excision by surgery. In one embodiment, the method comprises the steps of: removing a biopsy sample from the tissue of interest; placing a magnetic marker at the biopsy site; performing a pathology analysis of the biopsy sample; and if the pathology analysis indicates that the tissue of interest should be removed, locating the tissue for surgery using a magnetic detection probe. In one embodiment, the marker comprises magnetic nanoparticles in a bioabsorbable matrix. A system for preparing tissue of interest in a patient for possible excision by surgery. In one embodiment, the system includes a magnetic marker and magnetic detection probe system.

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