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公开(公告)号：US20060040388A1
公开(公告)日：2006-02-23
申请号：US11017433
申请日：2004-12-20
Applicant: Lev Bromberg , T. Hatton , I. Wang , Jin Yin , Bernat Olle
Inventor： Lev Bromberg , T. Hatton , I. Wang , Jin Yin , Bernat Olle
CPC classification number: C12P1/00 , B01D53/14 , B01J20/28007 , B01J20/28009 , B01J20/28016 , B01J20/28026 , B01J20/3204 , B01J20/3248 , B01J20/3251 , B01J20/3253 , B01J20/3255 , B01J20/3272 , B01J20/3274 , B01J20/3276 , B01J20/3282 , B01J20/3289 , B01J20/3293 , B82Y25/00 , B82Y30/00 , C01G49/08 , H01F1/0054 , Y10S977/773 , Y10S977/775 , Y10S977/811 , Y10T428/29 , Y10T428/294 , Y10T428/2942 , Y10T428/2971 , Y10T428/2991 , Y10T428/2998
Abstract: One aspect of the present invention relates to magnetic nanoparticles colloidally stabilized in aqueous milieu by association with an organic phase. The organic phase may be either a fluorinated polymer or an organic hydrocarbon bilayer, wherein the two layers are chemically bonded to each other. The stabilized particles are further non-toxic and provide useful enhancements in bioprocesses. Another aspect of the present invention relates to compositions comprising an oxygen-dissolving fluid vehicle and surface modified, nanometer-sized magnetic particles. The inventive compositions have utility in a wide range of applications, but are particularly suitable for use as recyclable oxygen carriers, separation and purification vehicles, and bioprocessing media, including fermentation processes.
Abstract translation: 本发明的一个方面涉及通过与有机相结合而在水溶液中胶体稳定的磁性纳米颗粒。 有机相可以是氟化聚合物或有机烃双层，其中两个层彼此化学键合。 稳定化的颗粒是进一步无毒的并且在生物过程中提供有用的增强。 本发明的另一方面涉及包含氧溶解流体载体和表面改性的纳米级磁性颗粒的组合物。 本发明的组合物在广泛的应用中具有实用性，但特别适合用作可回收的氧载体，分离和纯化载体以及生物处理介质，包括发酵方法。
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公开(公告)号：US07208134B2
公开(公告)日：2007-04-24
申请号：US11017433
申请日：2004-12-20
Applicant: Lev E. Bromberg , T. Alan Hatton , Daniel I. C. Wang , Jin Yin , Bernat Olle
Inventor： Lev E. Bromberg , T. Alan Hatton , Daniel I. C. Wang , Jin Yin , Bernat Olle
CPC classification number: C12P1/00 , B01D53/14 , B01J20/28007 , B01J20/28009 , B01J20/28016 , B01J20/28026 , B01J20/3204 , B01J20/3248 , B01J20/3251 , B01J20/3253 , B01J20/3255 , B01J20/3272 , B01J20/3274 , B01J20/3276 , B01J20/3282 , B01J20/3289 , B01J20/3293 , B82Y25/00 , B82Y30/00 , C01G49/08 , H01F1/0054 , Y10S977/773 , Y10S977/775 , Y10S977/811 , Y10T428/29 , Y10T428/294 , Y10T428/2942 , Y10T428/2971 , Y10T428/2991 , Y10T428/2998
Abstract: One aspect of the present invention relates to magnetic nanoparticles colloidally stabilized in aqueous milieu by association with an organic phase. The organic phase may be either a fluorinated polymer or an organic hydrocarbon bilayer, wherein the two layers are chemically bonded to each other. The stabilized particles are further non-toxic and provide useful enhancements in bioprocesses. Another aspect of the present invention relates to compositions comprising an oxygen-dissolving fluid vehicle and surface modified, nanometer-sized magnetic particles. The inventive compositions have utility in a wide range of applications, but are particularly suitable for use as recyclable oxygen carriers, separation and purification vehicles, and bioprocessing media, including fermentation processes.
Abstract translation: 本发明的一个方面涉及通过与有机相结合而在水溶液中胶体稳定的磁性纳米颗粒。 有机相可以是氟化聚合物或有机烃双层，其中两个层彼此化学键合。 稳定化的颗粒是进一步无毒的并且在生物过程中提供有用的增强。 本发明的另一方面涉及包含氧溶解流体载体和表面改性的纳米尺寸磁性颗粒的组合物。 本发明的组合物在广泛的应用中具有实用性，但特别适合用作可回收的氧载体，分离和纯化载体以及生物处理介质，包括发酵方法。
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