Aqueous suspensions of submicron 9-hydroxyrisperidone fatty acid esters
    3.
    发明授权
    Aqueous suspensions of submicron 9-hydroxyrisperidone fatty acid esters 有权
    亚微米9-羟基利培酮脂肪酸酯的水悬浮液

    公开(公告)号:US09320707B2

    公开(公告)日:2016-04-26

    申请号:US13538469

    申请日:2012-06-29

    摘要: The present invention is concerned with a pharmaceutical composition suitable as a depot formulation for administration via intramuscular or subcutaneous injection, comprising: (1) as an active ingredient a therapeutically effective amount of a 9-hydroxyrisperidone fatty acid ester or a salt, or a stereoisomer or a stereoisomeric mixture thereof in submicron form and (2) a pharmaceutically acceptable carrier; wherein the pharmaceutically acceptable carrier is water and the active ingredient is suspended therein: and with a process of preparing such a composition. The invention further concerns such a pharmaceutical composition for use as a medicament in the treatment of psychosis, schizophrenia, schizoaffective disorders, non-schizophrenic psychoses, behavioral disturbances associated with neurodegenerative disorders, e.g. in dementia, behavioral disturbances in mental retardation and autism, Tourette's syndrome, bipolar mania, depression, anxiety.

    摘要翻译: 本发明涉及适合作为通过肌内或皮下注射给药的贮库制剂的药物组合物,其包含:(1)作为活性成分的治疗有效量的9-羟基利培酮脂肪酸酯或其盐或立体异构体 或其亚微米形式的立体异构混合物和(2)药学上可接受的载体; 其中药学上可接受的载体是水,并且活性成分悬浮在其中;以及制备这种组合物的方法。 本发明还涉及用作治疗精神病,精神分裂症,分裂情感障碍,非精神分裂症性精神病,与神经变性疾病相关的行为障碍的药物组合物。 在痴呆症,精神发育迟滞和自闭症行为障碍,图雷特综合征,双相躁狂症,抑郁症,焦虑症。

    Method of producing nanophosphor particles
    9.
    发明授权
    Method of producing nanophosphor particles 有权
    生产纳米荧光粉颗粒的方法

    公开(公告)号:US08894957B2

    公开(公告)日:2014-11-25

    申请号:US12292894

    申请日:2008-11-28

    IPC分类号: C01F17/00 C09K11/77

    摘要: Provided is a method of producing spherical nanophosphor particles having a uniform size distribution. When nanophosphor obtained using the method is used in a flat panel display, the flat panel display has higher screen brightness and a higher resolution.

    摘要翻译: 提供具有均匀尺寸分布的球形纳米荧光体颗粒的制造方法。 当使用该方法获得的纳米荧光体用于平板显示器时,平板显示器具有较高的屏幕亮度和更高的分辨率。

    Luminescent conducting nano-drug crystal ultra-thin film self-assembly and uses
    10.
    发明授权
    Luminescent conducting nano-drug crystal ultra-thin film self-assembly and uses 有权
    发光导电纳米药物晶体超薄膜自组装和使用

    公开(公告)号:US08889188B2

    公开(公告)日:2014-11-18

    申请号:US11813265

    申请日:2005-12-29

    申请人: Yan Fang

    发明人: Yan Fang

    摘要: This invention involves two fields of photoelectron information materials and pharmaceuticals, especially refers to the self-assembly of conducting photoluminescence nanomedicine crystals and thin films and their preparation processes. In the invention, self-assembling unitary, binary, ternary and quaternary complexes of an antioxidase antioxidant, an agonist of the β-adrenergic receptors, an agonist of the P2-purinergic receptors and an antagonist of benzalkonium-typed calcium channels is to employ an interaction of inelastic electron tunneling, which possesses photoelectron properties of inelastic electron tunneling and photoluminescence with the central wavelength ˜500 nm and the wavelength wide ˜200 nm in the size-controlled square or cubic geometrical complexes. The invention is not only beneficial for drug discovery targeted disease mechanisms, but also profitable for inventions of photoelectron sensing new materials.

    摘要翻译: 本发明涉及光电子信息材料和药物的两个领域,特别是指导电光致发光纳米医药晶体和薄膜的自组装及其制备方法。 在本发明中,抗氧化酶抗氧化剂,β-肾上腺素能受体的激动剂,P2-嘌呤能受体的激动剂和苯扎氯铵型钙通道的拮抗剂的自组装单一,二元,三元和四价复合物是采用 非弹性电子隧道的相互作用,其具有在大小控制的正方形或立方几何复合物中具有中心波长〜500nm和波长宽〜200nm的非弹性电子隧道和光致发光的光电子性质。 本发明不仅有利于药物发现靶向疾病机制,而且对于光电子感测新材料的发明也是有利的。