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公开(公告)号：US20110099647A1
公开(公告)日：2011-04-28
申请号：US12886930
申请日：2010-09-21
Applicant: Michel DE WEERS , Yvo GRAUS , Judith OPRINS , Paul PARREN , Jan VAN DE WINKEL , Martine VAN VUGT
Inventor： Michel DE WEERS , Yvo GRAUS , Judith OPRINS , Paul PARREN , Jan VAN DE WINKEL , Martine VAN VUGT
IPC: A01K67/00 , A61K49/00 , A61K39/395 , G01N33/53 , C12N5/16 , C12N5/02 , C07K16/18 , C07H21/00 , A01H5/00 , A61P35/00 , A61P43/00
CPC classification number: C07K16/40 , A61K39/3955 , A61K45/06 , A61K49/0004 , A61K2039/505 , C07K14/70596 , C07K16/2896 , C07K2317/21 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/77 , C07K2317/92 , G01N33/566 , G01N2333/70596
Abstract: Isolated human monoclonal antibodies which bind to human CD38, and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.
Abstract translation: 公开了与人CD38结合的分离的人单克隆抗体以及相关的基于抗体的组合物和分子。 还公开了包含人抗体的药物组合物，以及使用人抗体的治疗和诊断方法。
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公开(公告)号：US20090148449A1
公开(公告)日：2009-06-11
申请号：US11886932
申请日：2006-03-23
Applicant: Michel De Weers , Yvo Graus , Judith Oprins , Paul Parren , Jan Van De Winkel , Martine Van Vugt
Inventor： Michel De Weers , Yvo Graus , Judith Oprins , Paul Parren , Jan Van De Winkel , Martine Van Vugt
IPC: A61K39/395 , C07K16/18 , C12N15/11 , C12N15/00 , C12N5/06 , G01N33/574 , A61K31/7088 , C12N1/21 , A01K67/027 , A01H5/00
CPC classification number: C07K16/40 , A61K39/3955 , A61K45/06 , A61K49/0004 , A61K2039/505 , C07K14/70596 , C07K16/2896 , C07K2317/21 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/77 , C07K2317/92 , G01N33/566 , G01N2333/70596
Abstract: Isolated human monoclonal antibodies which bind to human CD38, and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.
Abstract translation: 公开了与人CD38结合的分离的人单克隆抗体以及相关的基于抗体的组合物和分子。 还公开了包含人抗体的药物组合物，以及使用人抗体的治疗和诊断方法。
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Patent Agency Ranking
公开(公告)号：US09187565B2
公开(公告)日：2015-11-17
申请号：US12886930
申请日：2010-09-21
Applicant: Michel De Weers , Yvo Graus , Judith Oprins , Paul Parren , Jan Van De Winkel , Martine Van Vugt
Inventor： Michel De Weers , Yvo Graus , Judith Oprins , Paul Parren , Jan Van De Winkel , Martine Van Vugt
IPC: A61K38/00 , C07K16/28 , C07K14/705 , A61K39/00
CPC classification number: C07K16/40 , A61K39/3955 , A61K45/06 , A61K49/0004 , A61K2039/505 , C07K14/70596 , C07K16/2896 , C07K2317/21 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/77 , C07K2317/92 , G01N33/566 , G01N2333/70596
Abstract: Isolated human monoclonal antibodies which bind to human CD38, and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.
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公开(公告)号：US09040050B2
公开(公告)日：2015-05-26
申请号：US12442808
申请日：2007-09-26
Applicant: Jan Van De Winkel , Paul Parren , Yvo Graus , Judith Oprins , Michel De Weers , Martine Van Vugt , Ole Baadsgaard , Steen Lisby
Inventor： Jan Van De Winkel , Paul Parren , Yvo Graus , Judith Oprins , Michel De Weers , Martine Van Vugt , Ole Baadsgaard , Steen Lisby
IPC: A61K39/395 , C07K16/28 , A61K45/06 , A61K39/00
CPC classification number: C07K16/2896 , A61K39/39558 , A61K45/06 , A61K2039/505 , C07K2317/34 , A61K2300/00
Abstract: The invention relates to novel method for the treatment of cancer using a combination therapy comprising an antibody that binds CD38, a corticosteroid and a non-corticosteroid chemotherapeutic agent.
Abstract translation: 本发明涉及使用包含结合CD38的抗体，皮质类固醇和非皮质类固醇化学治疗剂的组合疗法治疗癌症的新方法。
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公开(公告)号：US20100092489A1
公开(公告)日：2010-04-15
申请号：US12442808
申请日：2007-09-26
Applicant: Jan Van De Winkel , Paul Parren , Yvo Graus , Judith Oprins , Michel De Weers , Martine Van Vugt , Ole Baadsgaard , Steen Lisby
Inventor： Jan Van De Winkel , Paul Parren , Yvo Graus , Judith Oprins , Michel De Weers , Martine Van Vugt , Ole Baadsgaard , Steen Lisby
IPC: A61K39/395 , A61P35/00
CPC classification number: C07K16/2896 , A61K39/39558 , A61K45/06 , A61K2039/505 , C07K2317/34 , A61K2300/00
Abstract: The invention relates to novel method for the treatment of cancer using a combination therapy comprising an antibody that binds CD38, a corticosteroid and a non- corticosteroid chemotherapeutic agent.
Abstract translation: 本发明涉及使用包含结合CD38的抗体，皮质类固醇和非皮质类固醇化学治疗剂的组合疗法治疗癌症的新方法。
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公开(公告)号：US07829673B2
公开(公告)日：2010-11-09
申请号：US11886932
申请日：2006-03-23
Applicant: Michel De Weers , Yvo Graus , Judith Oprins , Paul Parren , Jan Van De Winkel , Martine Van Vugt
Inventor： Michel De Weers , Yvo Graus , Judith Oprins , Paul Parren , Jan Van De Winkel , Martine Van Vugt
CPC classification number: C07K16/40 , A61K39/3955 , A61K45/06 , A61K49/0004 , A61K2039/505 , C07K14/70596 , C07K16/2896 , C07K2317/21 , C07K2317/34 , C07K2317/56 , C07K2317/565 , C07K2317/732 , C07K2317/734 , C07K2317/76 , C07K2317/77 , C07K2317/92 , G01N33/566 , G01N2333/70596
Abstract: Isolated human monoclonal antibodies which bind to human CD38, and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.
Abstract translation: 公开了与人CD38结合的分离的人单克隆抗体以及相关的基于抗体的组合物和分子。 还公开了包含人抗体的药物组合物，以及使用人抗体的治疗和诊断方法。
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公开(公告)号：US20090076249A1
公开(公告)日：2009-03-19
申请号：US11901953
申请日：2007-09-19
Applicant: Michel De Weers , Yvo Graus , Judith Oprins , Paul Parren , Jan Van De Winkel , Martine Van Vugt
Inventor： Michel De Weers , Yvo Graus , Judith Oprins , Paul Parren , Jan Van De Winkel , Martine Van Vugt
IPC: C07K16/18
CPC classification number: C07K16/2896 , C07K2317/34 , C07K2317/56 , C07K2317/73 , C07K2317/92
Abstract: Isolated human monoclonal antibodies which bind to human CD38, and related antibody-based compositions and molecules, are disclosed. Also disclosed are pharmaceutical compositions comprising the human antibodies, and therapeutic and diagnostic methods for using the human antibodies.
Abstract translation: 公开了与人CD38结合的分离的人单克隆抗体以及相关的基于抗体的组合物和分子。 还公开了包含人抗体的药物组合物，以及使用人抗体的治疗和诊断方法。
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