利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

21 条记录 (耗时 0.015 秒)

    Method for producing human antibodies to a self physiological receptor by site-directed in vitro immunization of human lymphocytes
    2.
    发明授权
    Method for producing human antibodies to a self physiological receptor by site-directed in vitro immunization of human lymphocytes 有权
    通过人淋巴细胞的定点体外免疫产生人自身抗体的方法

    公开(公告)号：US08021860B2

    公开(公告)日：2011-09-20

    申请号：US12318679

    申请日：2009-01-06

    申请人： Li-Te Chin ,  Shu-Ching Hsu

    发明人： Li-Te Chin ,  Shu-Ching Hsu

    IPC分类号： C12P21/04

    CPC分类号： G01N33/5052 ,  A61K2039/505 ,  C07K16/00 ,  C07K16/2818 ,  C07K2317/73 ,  C07K2317/74 ,  G01N33/505 ,  G01N33/6854 ,  G01N2333/70521

    摘要： A method for obtaining agonist, antagonist and inverse agonist, to a given physiological receptor is disclosed. For the method, use is made of in silico design synthetic immunogens, which are caused to act in vitro on human lymphocyte-containing cell populations. A preferred receptor is human CD152, particularly the regions of CDR1, CDR2 and CDR3 that elicit antibodies serving as antagonist, inverse agonist and agonist, respectively. Also provided is a method in the treatment of human peripheral lymphocytes for use in the screening of CD152 ligands that yield pharmacological effects.

    摘要翻译： 公开了一种获得给定生理受体的激动剂，拮抗剂和反向激动剂的方法。 对于该方法，使用计算机设计合成免疫原，其在体外对人类含淋巴细胞的细胞群体起作用。 优选的受体是人CD152，特别是分别引发作为拮抗剂，反向激动剂和激动剂的抗体的CDR1，CDR2和CDR3的区域。 还提供了治疗人外周淋巴细胞用于筛选产生药理作用的CD152配体的方法。

    Method For Producing Human Antibodies With Properties Of Agonist, Antagonist, or Inverse Agonist
    3.
    发明申请
    Method For Producing Human Antibodies With Properties Of Agonist, Antagonist, or Inverse Agonist 有权
    用激动剂，拮抗剂或反激动剂的性质产生人类抗体的方法

    公开(公告)号：US20110033895A1

    公开(公告)日：2011-02-10

    申请号：US12888713

    申请日：2010-09-23

    申请人： Li-Te CHIN ,  Shu-Ching Hsu

    发明人： Li-Te CHIN ,  Shu-Ching Hsu

    IPC分类号： C12P21/08

    CPC分类号： G01N33/5052 ,  A61K2039/505 ,  C07K16/00 ,  C07K16/2818 ,  C07K2317/73 ,  C07K2317/74 ,  G01N33/505 ,  G01N33/6854 ,  G01N2333/70521

    摘要： A method for obtaining agonist, antagonist and inverse agonist, to a given physiological receptor is disclosed. For the method, use is made of in silico design synthetic immunogens, which are caused to act in vitro on human lymphocyte-containing cell populations. A preferred receptor is human CD152, particularly the regions of CDR1, CDR2 and CDR3 that elicit antibodies serving as antagonist, inverse agonist and agonist, respectively. Also provided is a method in the treatment of human peripheral lymphocytes for use in the screening of CD152 ligands that yield pharmacological effects.

    摘要翻译： 公开了一种获得给定生理受体的激动剂，拮抗剂和反向激动剂的方法。 对于该方法，使用计算机设计合成免疫原，其在体外对人类含淋巴细胞的细胞群体起作用。 优选的受体是人CD152，特别是分别引发作为拮抗剂，反向激动剂和激动剂的抗体的CDR1，CDR2和CDR3的区域。 还提供了治疗人外周淋巴细胞用于筛选产生药理作用的CD152配体的方法。

    Method for producing human antibodies with properties of agonist, antagonist, or inverse agonist
    4.
    发明申请
    Method for producing human antibodies with properties of agonist, antagonist, or inverse agonist 有权
    用于产生具有激动剂，拮抗剂或反向激动剂的性质的人抗体的方法

    公开(公告)号：US20090286224A1

    公开(公告)日：2009-11-19

    申请号：US12318679

    申请日：2009-01-06

    申请人： Li-Te Chin ,  Shu-Ching Hsu

    发明人： Li-Te Chin ,  Shu-Ching Hsu

    IPC分类号： C12Q1/70 ,  G01N33/53 ,  C07K7/00 ,  C07K16/28

    CPC分类号： G01N33/5052 ,  A61K2039/505 ,  C07K16/00 ,  C07K16/2818 ,  C07K2317/73 ,  C07K2317/74 ,  G01N33/505 ,  G01N33/6854 ,  G01N2333/70521

    摘要： A method for obtaining agonist, antagonist and inverse agonist, to a given physiological receptor is disclosed. For the method, use is made of in silico design synthetic immunogens, which are caused to act in vitro on human lymphocyte-containing cell populations. A preferred receptor is human CD152, particularly the regions of CDR1, CDR2 and CDR3 that elicit antibodies serving as antagonist, inverse agonist and agonist, respectively. Also provided is a method in the treatment of human peripheral lymphocytes for use in the screening of CD152 ligands that yield pharmacological effects.

    摘要翻译： 公开了一种获得给定生理受体的激动剂，拮抗剂和反向激动剂的方法。 对于该方法，使用计算机设计合成免疫原，其在体外对人类含淋巴细胞的细胞群体起作用。 优选的受体是人CD152，特别是分别引发作为拮抗剂，反向激动剂和激动剂的抗体的CDR1，CDR2和CDR3的区域。 还提供了治疗人外周淋巴细胞用于筛选产生药理作用的CD152配体的方法。

    APPARATUS FOR CLEANING ENVIRONMENTAL AIR USING ANTISEPTICS AND DISINFECTANTS
    5.
    发明申请
    APPARATUS FOR CLEANING ENVIRONMENTAL AIR USING ANTISEPTICS AND DISINFECTANTS 有权

    公开(公告)号：US20230109935A1

    公开(公告)日：2023-04-13

    申请号：US17953468

    申请日：2022-09-27

    申请人： Shu-Ching HSU ,  Li-Te CHIN

    发明人： Shu-Ching HSU ,  Li-Te CHIN

    IPC分类号： A61L9/14

    摘要： An apparatus for countercurrent exchange, including: a conduit, including: a side wall; an inner space; an air outlet disposed on a first end of the conduit; a liquid miniaturization device disposed in the inner space of the conduit near the air outlet, wherein the liquid miniaturization device is used to spray a liquid in a liquid direction; an air intake disposed on the side wall near a second end of the conduit; and a reservoir portion disposed in the inner space near the second end of the conduit for storing the liquid; a pneumatic conveyor connected with the air intake for introducing air into the conduit along an air flow direction; and a pumping device connected with the reservoir portion by a first tube, wherein the liquid direction is opposite to the air flow direction in the conduit.

    METHOD OF PROMOTING HAIR GROWTH
    6.
    发明申请
    METHOD OF PROMOTING HAIR GROWTH 有权
    促进头发生长的方法

    公开(公告)号：US20110263618A1

    公开(公告)日：2011-10-27

    申请号：US12766927

    申请日：2010-04-26

    申请人： Han-Min Chen ,  Li-Te Chin

    发明人： Han-Min Chen ,  Li-Te Chin

    IPC分类号： A61K8/40 ,  A61Q7/00

    CPC分类号： A61Q7/00 ,  A61K8/4953 ,  A61K31/52 ,  A61Q5/02 ,  A61Q5/12

    摘要： The present invention is an invention belonging to the life style improving cosmetic in the field of hair maintenance and enrichment. More particularly, it relates to cosmetic compositions having an improved hair care actions such as to prevent hair loss and/or to promote hair growth on the scalp and skin of a mammal.

    摘要翻译： 本发明是属于改善头发维护和浓缩领域的化妆品的生活方式的发明。 更具体地说，本发明涉及具有改善的头发护理作用的化妆品组合物，例如防止脱发和/或促进哺乳动物的头皮和皮肤上的毛发生长。

    Sanitary utensil with functions of immuno-chromatographic test and indication
    8.
    发明申请
    Sanitary utensil with functions of immuno-chromatographic test and indication 审中-公开
    卫生洁具，具有免疫色谱检测和指示功能

    公开(公告)号：US20060258020A1

    公开(公告)日：2006-11-16

    申请号：US11125227

    申请日：2005-05-10

    申请人： Yi-Feng Kao ,  Ching-Yu Lin ,  Peter Chan ,  Li-Te Chin ,  Ying-Chih Wang

    发明人： Yi-Feng Kao ,  Ching-Yu Lin ,  Peter Chan ,  Li-Te Chin ,  Ying-Chih Wang

    IPC分类号： G01N33/558

    CPC分类号： G01N33/558 ,  G01N33/528

    摘要： The present invention discloses a sanitary utensil with functions of immuno-chromatographic test and indication, which comprises at least one immuno-chromatographic test piece and at least one cover having an open end. The immuno-chromatographic test piece further comprises a test starting portion, an indicating portion and a test stopping portion. Furthermore, the cover is used to protect the test stopping portion, the indicating portion and part of the test starting portion, so that the bio-specimen is allowed to enter the immuno-chromatographic testing piece only from the test starting portion.

    摘要翻译： 本发明公开了一种具有免疫色谱测试和指示功能的卫生器具，其包括至少一个免疫色谱测试片和至少一个具有开放端的盖。 免疫色谱试片还包括测试起始部分，指示部分和测试停止部分。 此外，盖子用于保护测试停止部分，指示部分和测试起始部分的一部分，使得生物样本仅允许从测试起始部分进入免疫色谱测试部件。