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公开(公告)号:US20130039938A1
公开(公告)日:2013-02-14
申请号:US13280043
申请日:2011-10-24
Applicant: Gale SMITH , Yingyun Wu , Michael Massare , Peter Pushko , Margret Nathan , Thomas Kort , Robin Robinson
Inventor: Gale SMITH , Yingyun Wu , Michael Massare , Peter Pushko , Margret Nathan , Thomas Kort , Robin Robinson
IPC: A61K39/145 , C12P21/02 , C12N9/24 , C07K14/11 , A61P37/04
CPC classification number: C12N7/00 , A61K39/12 , A61K2039/5258 , A61K2039/55505 , A61K2039/55555 , C07K14/005 , C07K2319/01 , C07K2319/03 , C12N9/2402 , C12N2710/14143 , C12N2760/16122 , C12N2760/16123 , C12N2760/16134 , C12N2760/16151 , C12N2760/16171 , C12N2760/16222 , C12N2760/16223 , C12N2760/16251 , C12N2770/20022 , C12N2770/20023 , C12N2770/20051 , C12N2800/22 , C12Y302/01018
Abstract: This invention discloses a method of increasing production of virus-like particles comprising expressing an avian influenza matrix protein. The invention also comprises methods of making and using said VLPs.
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公开(公告)号:US08715692B2
公开(公告)日:2014-05-06
申请号:US12633995
申请日:2009-12-09
Applicant: Peter Pushko , Yingyun Wu , Michael Massare , Ye Liu , Gale Smith , Bin Zhou
Inventor: Peter Pushko , Yingyun Wu , Michael Massare , Ye Liu , Gale Smith , Bin Zhou
IPC: A61K39/155 , C07K14/135 , C12N15/40 , C12N5/10
CPC classification number: A61K39/155 , A61K9/0019 , A61K9/1075 , A61K39/00 , A61K39/12 , A61K39/39 , A61K2039/5258 , A61K2039/54 , A61K2039/545 , A61K2039/55 , A61K2039/55505 , A61K2039/57 , A61K2039/575 , C07K14/005 , C07K2319/00 , C12N7/00 , C12N2760/18522 , C12N2760/18523 , C12N2760/18534 , C12N2760/18562 , C12N2760/18571
Abstract: The present invention is generally related to modified or mutated respiratory syncytial virus fusion (F) proteins and methods for making and using them, including immunogenic compositions such as vaccines for the treatment and/or prevention of RSV infection.
Abstract translation: 本发明通常涉及修饰或突变的呼吸道合胞病毒融合(F)蛋白及其制备及使用方法,包括用于治疗和/或预防RSV感染的疫苗等免疫原性组合物。
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公开(公告)号:US20130122032A1
公开(公告)日:2013-05-16
申请号:US13629107
申请日:2012-09-27
Applicant: Gale SMITH , Yingyun Wu , Michael Massare , Ye Liu
Inventor: Gale SMITH , Yingyun Wu , Michael Massare , Ye Liu
IPC: C07K14/135 , A61K39/155
CPC classification number: A61K39/155 , A61K39/12 , A61K2039/5258 , A61K2039/54 , A61K2039/55505 , A61K2039/55555 , C07K14/005 , C07K14/135 , C12N7/00 , C12N2760/18522 , C12N2760/18534
Abstract: The present invention is generally related to modified or mutated respiratory syncytial virus fusion (F) proteins and methods for making and using them, including immunogenic compositions such as vaccines for the treatment and/or prevention of RSV infection.
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公开(公告)号:US08992939B2
公开(公告)日:2015-03-31
申请号:US13280043
申请日:2011-10-24
Applicant: Gale Smith , Yingyun Wu , Michael Massare , Peter Pushko , Margret Nathan , Thomas Kort , Robin Robinson
Inventor: Gale Smith , Yingyun Wu , Michael Massare , Peter Pushko , Margret Nathan , Thomas Kort , Robin Robinson
CPC classification number: C12N7/00 , A61K39/12 , A61K2039/5258 , A61K2039/55505 , A61K2039/55555 , C07K14/005 , C07K2319/01 , C07K2319/03 , C12N9/2402 , C12N2710/14143 , C12N2760/16122 , C12N2760/16123 , C12N2760/16134 , C12N2760/16151 , C12N2760/16171 , C12N2760/16222 , C12N2760/16223 , C12N2760/16251 , C12N2770/20022 , C12N2770/20023 , C12N2770/20051 , C12N2800/22 , C12Y302/01018
Abstract: This invention discloses a method of increasing production of virus-like particles comprising expressing an avian influenza matrix protein. The invention also comprises methods of making and using said VLPs.
Abstract translation: 本发明公开了一种增加包含表达禽流感基因蛋白质的病毒样颗粒的生产的方法。 本发明还包括制备和使用所述VLP的方法。
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公开(公告)号:US20100239617A1
公开(公告)日:2010-09-23
申请号:US12633995
申请日:2009-12-09
Applicant: Peter PUSHKO , Yingyun Wu , Michael Massare , Ye Liu , Gale Smith , Bin Zhou
Inventor: Peter PUSHKO , Yingyun Wu , Michael Massare , Ye Liu , Gale Smith , Bin Zhou
IPC: A61K39/155 , C07K14/135 , C07H21/02 , C12N5/10 , C12N7/00 , A61K9/00 , A61P31/14
CPC classification number: A61K39/155 , A61K9/0019 , A61K9/1075 , A61K39/00 , A61K39/12 , A61K39/39 , A61K2039/5258 , A61K2039/54 , A61K2039/545 , A61K2039/55 , A61K2039/55505 , A61K2039/57 , A61K2039/575 , C07K14/005 , C07K2319/00 , C12N7/00 , C12N2760/18522 , C12N2760/18523 , C12N2760/18534 , C12N2760/18562 , C12N2760/18571
Abstract: The present invention is generally related to modified or mutated respiratory syncytial virus fusion (F) proteins and methods for making and using them, including immunogenic compositions such as vaccines for the treatment and/or prevention of RSV infection.
Abstract translation: 本发明通常涉及修饰或突变的呼吸道合胞病毒融合(F)蛋白及其制备及使用方法,包括用于治疗和/或预防RSV感染的疫苗等免疫原性组合物。
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