PHARMACEUTICAL FORMULATION CONTAINING REMDESIVIR

    公开(公告)号:US20210252027A1

    公开(公告)日:2021-08-19

    申请号:US17168262

    申请日:2021-02-05

    申请人: Cai Gu Huang Ning He

    发明人: Cai Gu Huang Ning He

    摘要: The present invention relates to a liquid pharmaceutical preparation and a method for administering the pharmaceutical preparation by nebulization or soft mist inhalation. The pharmaceutical formulation comprises: (a) remdesivir or a pharmaceutically acceptable salt thereof; (b) an excipient selected from the group consisting of (i) a pharmacologically acceptable stabilizer or complexing agent and (ii) a solubility enhancing agent; and (c) a solvent wherein the pharmaceutical formulation has a pH of between about 2.0 and about 6.0.

    INTERMITTENT FAILURE METRICS IN TECHNOLOGICAL PROCESSES

    公开(公告)号:US20190243753A1

    公开(公告)日:2019-08-08

    申请号:US16263363

    申请日:2019-01-31

    IPC分类号: G06F11/36 G06F9/50 G06F17/11

    摘要: Systems and methods for testing a subject system with a software testing process are described. The system receives Boolean states responsive to repeatedly applying a first test case to a subject system. Each Boolean state signifies an outcome of an application of the first test case to a version of a first software feature over a span of time. The system identifies test case outcomes for the first test case that are adjacent in time and different and generates an intermittency value for the first test case. The system determines that the intermittency value for the first test case exceeds an intermittency threshold and alerts an engineering resource. Finally, the system repeats the above operations until the intermittency value for the first test case does not exceed the intermittency threshold.

    Preferential allocation of different length scrambling codes

    公开(公告)号:US09641360B2

    公开(公告)日:2017-05-02

    申请号:US13163270

    申请日:2011-06-17

    摘要: A base station herein assists a radio network controller (RNC) to allocate scrambling codes in a cell. The base station's assistance advantageously permits the RNC to allocate different length scrambling codes to different mobile terminals (or downlink carriers) in the cell. Specifically, the base station determines a preference for whether the length of a scrambling code to be allocated to each terminal or carrier should be short or long, based on whether uplink communications transmitted by the terminal, or downlink communications transmitted over the carrier, are to be processed with a high-complexity receiver or a low-complexity receiver. The RNC receives these preferences from the base station and takes them into account in order to allocate either a short scrambling code or a long scrambling code to each terminal or downlink carrier in the cell. The RNC then propagates the scrambling code allocations throughout the cell.

    Method and apparatus for communication signal processing based on mixed parametric and non-parametric estimation of impairment correlations
    5.
    发明授权
    Method and apparatus for communication signal processing based on mixed parametric and non-parametric estimation of impairment correlations 有权
    基于混合参数和非参数估计损伤相关性的通信信号处理方法和装置

    公开(公告)号:US08295330B2

    公开(公告)日:2012-10-23

    申请号:US12177498

    申请日:2008-07-22

    IPC分类号: H04B1/00

    CPC分类号: H04B1/712 H04B2201/709727

    摘要: According to the teachings presented herein, a method and apparatus for communication signal processing advantageously use a mix of parametric and non-parametric correlation estimation in communication signal processing. Non-parametric estimation generates an “overall” correlation estimate for a received communication signal, and parametric estimation generates a “component” correlation estimate. The component correlation estimate is removed from the overall correlation estimate to form a partial correlation estimate that is used to process the received communication signal at least initially, such as in a pre-equalization stage. The overall and component correlation estimates are generated as impairment and/or data correlation estimates.

    摘要翻译: 根据本文给出的教导,用于通信信号处理的方法和装置有利地在通信信号处理中使用参数和非参数相关估计的混合。 非参数估计对接收到的通信信号产生总体相关估计,参数估计产生分量相关估计。 从总体相关估计中去除分量相关估计,以形成一个部分相关估计,该估计用于至少最初处理接收的通信信号,例如在预均衡阶段。 总体和分量相关估计是作为减值和/或数据相关估计产生的。

    Method and Arrangement in a Telecommunication System
    6.
    发明申请
    Method and Arrangement in a Telecommunication System 审中-公开
    电信系统中的方法和布置

    公开(公告)号:US20110105166A1

    公开(公告)日:2011-05-05

    申请号:US12997059

    申请日:2008-06-12

    申请人: Ning He Bo Hagerman

    发明人: Ning He Bo Hagerman

    IPC分类号: H04B7/00

    摘要: In a method of radio link handling in a radio base station (RBS) in a telecommunication system, said radio base station (RBS) supporting a plurality of mobile user equipment (UE) and comprising a plurality of antenna arrangements each associated with a respective determined cell coverage area. Performing the steps of actively determining (20) a respective local receive active set of cells or antennas for each of at least a subset of said plurality of mobile user equipment (UE). Finally, receiving and detecting (30) signals from each mobile user equipment (UE) jointly utilizing each said determined local receive active set.

    摘要翻译: 在电信系统中的无线电基站(RBS)中的无线电链路处理的方法中,所述无线基站(RBS)支持多个移动用户设备(UE),并且包括多个天线布置,每个天线布置与各自确定的 小区覆盖区域。 执行为所述多个移动用户设备(UE)的至少一个子集中的每一个主动地确定(20)相应的本地接收有效的小区或天线集合的步骤。 最后,从每个移动用户设备(UE)接收和检测(30)信号,联合利用每个所确定的本地接收活动集。

    Method of Closed Loop Power Control Adjusted by Self-Interference
    7.
    发明申请
    Method of Closed Loop Power Control Adjusted by Self-Interference 审中-公开
    通过自干扰调节闭环功率控制方法

    公开(公告)号:US20090190485A1

    公开(公告)日:2009-07-30

    申请号:US12022346

    申请日:2008-01-30

    IPC分类号: H04L1/00

    摘要: A method and apparatus for controlling the transmit power of a mobile device in a mobile communication network takes the level of self-interference into account to perform inner-loop power control. For normal inner-loop power control, a signal quality estimate is compared to a signal quality target and power control commands are generated based on the comparison. When self-interference is the dominant impairment in the received signal, a “fast break” is introduced to change inner-loop power control command generation.

    摘要翻译: 用于控制移动通信网络中的移动设备的发射功率的方法和装置考虑自干扰水平以执行内环功率控制。 对于正常的内环功率控制,将信号质量估计与信号质量目标进行比较,并且基于比较生成功率控制命令。 当自干扰是接收信号的主要损害时,引入“快断”来改变内环功率控制命令的产生。

    Diversity branch delay alignment in radio base station
    8.
    发明授权
    Diversity branch delay alignment in radio base station 失效
    无线电基站中的分集支路延迟对准

    公开(公告)号:US07043273B2

    公开(公告)日:2006-05-09

    申请号:US10045024

    申请日:2002-01-15

    IPC分类号: H04Q7/20

    摘要: A base station (28) included in a radio access network of a telecommunications system has two diversity antennas (44A, 44B) for a cell/carrier utilized in a sector served by the base station which are respectively involved in transmission of two branches of a radio link signal of the cell/carrier between the base station and a user equipment unit (30). Two branches of signal processing hardware respectively process the two branches of the radio link signal to yield two respective processed branches of the radio link signal. A rake receiver (62, 262) measures the delay difference between the two processed branches of the radio link signal, and uses the measured delay difference for various purposes. For example, some embodiments of the invention use the delay difference between the two branches as measured by the rake receiver to compensate for a delay difference which exists between the two processed branches of the radio link signal. When measuring the delay difference between the two branches of an uplink radio signal, a rake receiver (62) at the radio base station is employed. On the other hand, when measuring the delay difference between the two branches of a downlink radio signal, a rake receiver (262) at test user equipment unit (30T) is employed.

    摘要翻译: 包括在电信系统的无线电接入网络中的基站(28)具有用于由基站服务的扇区中使用的小区/载波的两个分集天线(44A,44B),其分别涉及两个分支的传输 在基站和用户设备单元(30)之间的小区/载波的无线电链路信号。 信号处理硬件的两个分支分别处理无线电链路信号的两个分支,以产生无线电链路信号的两个相应的处理分支。 耙式接收器(62,262)测量无线电链路信号的两个处理分支之间的延迟差,并且为了各种目的使用所测量的延迟差。 例如,本发明的一些实施例使用由耙式接收机测量的两个分支之间的延迟差来补偿存在于无线电链路信号的两个经处理的分支之间的延迟差异。 当测量上行链路无线电信号的两个分支之间的延迟差时,采用无线电基站处的瑞克接收机(62)。 另一方面,当测量下行链路无线电信号的两个分支之间的延迟差时,采用在测试用户设备单元(30T)处的瑞克接收机(262)。

    Adaptive path selection threshold setting for DS-CDMA receivers
    9.
    发明授权
    Adaptive path selection threshold setting for DS-CDMA receivers 失效
    DS-CDMA接收机的自适应路径选择阈值设置

    公开(公告)号:US06229842B1

    公开(公告)日:2001-05-08

    申请号:US09116263

    申请日:1998-07-16

    IPC分类号: H04B1707

    摘要: A system and method for detecting and selecting peaks in a delay power profile (DPP) signal. An adaptive threshold is used to determine valid paths in the DPP signal. The adaptive threshold is determined by measuring the signal-to-noise ratio of the DPP signal, and setting the threshold to minimize non-detections and false alarms in path estimation. To determine the signal-to-noise ratio, the system uses an iterative process wherein a raw estimate and an improved estimate are made of the noise.

    摘要翻译: 一种在延迟功率谱(DPP)信号中检测和选择峰值的系统和方法。 自适应阈值用于确定DPP信号中的有效路径。 通过测量DPP信号的信噪比来确定自适应阈值,并设置阈值以最小化路径估计中的非检测和误报警。 为了确定信噪比,系统使用迭代过程,其中原始估计和改进的估计是由噪声构成的。

    Water-injection foaming devolatilizing method
    10.
    发明授权
    Water-injection foaming devolatilizing method 失效
    注水发泡脱挥发分法

    公开(公告)号:US5630968A

    公开(公告)日:1997-05-20

    申请号:US474724

    申请日:1995-06-07

    IPC分类号: B29C47/76 B29C47/80 B29C44/00

    摘要: A water-injection foaming devolatilizing method includes the steps of: melting and kneading a polymer in a water-injection dispersing zone of an extruder having a screw; injecting water into a polymer melt so as to be dispersed into the polymer melt which is being kneaded; and vaporizing volatile components contained in the polymer melt together with water in a devolatilizing zone having a vent port and located on a downstream side of the water-injection dispersing zone, so that the volatile components are removed and discharged through the vent port. A pressure-reducing expansion zone is provided between the water-injection dispersing zone and the devolatilizing zone so as to be upstream of the vent port. The method further includes gradually reducing a pressure in the pressure-reducing expansion zone so that not only bubbles in the water which is dispersed into the polymer melt are made to grow up, but also the bubbles are broken down at a downstream end portion of the pressure-reducing expansion zone.

    摘要翻译: 注水发泡脱挥发分法包括以下步骤:在具有螺杆的挤出机的注水分散区中熔融和捏合聚合物; 将水注入聚合物熔体中以分散在正在捏合的聚合物熔体中; 并且包含在聚合物中的挥发性成分的蒸发与具有通气口并位于注水分散区的下游侧的脱挥发区一起与水一起熔化,从而通过排气口除去挥发性成分并排出。 在注水分散区和脱挥发区之间设有减压膨胀区,以便在通气口的上游。 该方法还包括逐渐降低减压膨胀区的压力,使得不仅使分散在聚合物熔体中的水中的气泡长大,而且气泡在下游端部分分解 减压膨胀区。