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公开(公告)号：US11666531B2
公开(公告)日：2023-06-06
申请号：US16087989
申请日：2017-03-31
发明人： Thomas Hnat
IPC分类号： A61K9/06 , A61K9/00 , A61K47/14 , A61K47/44 , A61K31/522 , A61K31/216 , A61K31/352 , A61K31/192 , A61K31/196 , A61K31/167 , A61K31/714 , A61K31/385 , A61K31/245 , A61K47/10 , A61K45/06
CPC分类号： A61K9/06 , A61K9/0014 , A61K31/167 , A61K31/192 , A61K31/196 , A61K31/216 , A61K31/245 , A61K31/352 , A61K31/385 , A61K31/522 , A61K31/714 , A61K45/06 , A61K47/10 , A61K47/14 , A61K47/44
摘要： In accordance with the present disclosure, there are provided formulations comprising: (a) at least one active agent; (b) an oil, and optionally a thickener therefor; (c) an organic solvent, and a thickener therefor; and (d) an oil and/or solvent soluble skin penetration enhancer; wherein: said formulation comprises
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公开(公告)号：US20230310318A1
公开(公告)日：2023-10-05
申请号：US18205995
申请日：2023-06-05
发明人： Thomas HNAT
IPC分类号： A61K9/06 , A61K9/00 , A61K47/14 , A61K47/44 , A61K31/522 , A61K31/216 , A61K31/352 , A61K31/192 , A61K31/196 , A61K31/167 , A61K31/714 , A61K31/385 , A61K31/245 , A61K47/10 , A61K45/06
CPC分类号： A61K9/06 , A61K9/0014 , A61K47/14 , A61K47/44 , A61K31/522 , A61K31/216 , A61K31/352 , A61K31/192 , A61K31/196 , A61K31/167 , A61K31/714 , A61K31/385 , A61K31/245 , A61K47/10 , A61K45/06
摘要： In accordance with the present disclosure, there are provided formulations comprising:
(a) at least one active agent;
(b) an oil, and optionally a thickener therefor;
(c) an organic solvent, and a thickener therefor; and
(d) an oil and/or solvent soluble skin penetration enhancer;
wherein:
said formulation comprises-
公开(公告)号：US20230233495A1
公开(公告)日：2023-07-27
申请号：US18152034
申请日：2023-01-09
发明人： Thomas HNAT
IPC分类号： A61K31/196 , A61K9/00 , A61K31/165 , A61K31/167 , A61K31/192 , A61K31/245 , A61K31/405 , A61K31/416 , A61K31/60 , A61K31/7034 , A61K47/10 , A61K47/12 , A61K47/20 , A61K47/38
CPC分类号： A61K31/196 , A61K9/0014 , A61K31/60 , A61K31/165 , A61K31/167 , A61K31/192 , A61K31/245 , A61K31/405 , A61K31/416 , A61K31/7034 , A61K47/10 , A61K47/12 , A61K47/20 , A61K47/38
摘要： A topical cyclooxygenase (COX) inhibitor formulation comprising an inhibitor of COX-1 and/or COX-2, one or more long chain monounsaturated fatty acids, long chain monounsaturated fatty alcohols, terpenes, or combinations thereof; and a solvent mixture comprising ethanol, propylene glycol, 2-(2-Ethoxyethoxy)ethanol, and optionally dimethylsulfoxide.
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公开(公告)号：US11872199B2
公开(公告)日：2024-01-16
申请号：US18152034
申请日：2023-01-09
发明人： Thomas Hnat
IPC分类号： A61K31/196 , A61K9/14 , A61K31/165 , A61K31/167 , A61K31/192 , A61K31/245 , A61K31/405 , A61K31/416 , A61K31/60 , A61K31/7034 , A61K47/10 , A61K47/12 , A61K47/20 , A61K47/38 , A61K9/00
CPC分类号： A61K31/196 , A61K9/0014 , A61K31/165 , A61K31/167 , A61K31/192 , A61K31/245 , A61K31/405 , A61K31/416 , A61K31/60 , A61K31/7034 , A61K47/10 , A61K47/12 , A61K47/20 , A61K47/38
摘要： A topical cyclooxygenase (COX) inhibitor formulation comprising an inhibitor of COX-1 and/or COX-2, one or more long chain monounsaturated fatty acids, long chain monounsaturated fatty alcohols, terpenes, or combinations thereof; and a solvent mixture comprising ethanol, propylene glycol, 2-(2-Ethoxyethoxy)ethanol, and optionally dimethylsulfoxide.
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公开(公告)号：US20220378729A1
公开(公告)日：2022-12-01
申请号：US17755770
申请日：2020-11-05
发明人： Thomas HNAT
IPC分类号： A61K31/196 , A61K9/00 , A61K47/12 , A61K47/10 , A61K47/38 , A61K47/20 , A61K31/192 , A61K31/167 , A61K31/405 , A61K31/60 , A61K31/7034 , A61K31/416 , A61K31/165 , A61K31/245
摘要： A topical cyclooxygenase (COX) inhibitor formulation comprising an inhibitor of COX-1 and/or COX-2, one or more long chain monounsaturated fatty acids, long chain monounsaturated fatty alcohols, terpenes, or combinations thereof; and a solvent mixture comprising ethanol, propylene glycol, 2-(2-Ethoxyethoxy)ethanol, and optionally dimethylsulfoxide.
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