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公开(公告)号:US20180170956A1
公开(公告)日:2018-06-21
申请号:US15900544
申请日:2018-02-20
发明人: Andre BENATTAR , Andrey BONNARDEL , Jerome GUILBOT , Sebastien KERVERDO , Herve ROLLAND , Guy TABACCHI
IPC分类号: C07H15/04 , A61Q1/14 , A61Q5/02 , C07D307/20 , A61Q19/10 , C07H1/00 , A61K8/60 , C07D493/04 , A61Q17/04 , A61Q19/00 , A61Q19/08 , A61Q19/04
CPC分类号: C07H15/04 , A61K8/602 , A61Q1/14 , A61Q5/02 , A61Q17/04 , A61Q19/00 , A61Q19/04 , A61Q19/08 , A61Q19/10 , C07D307/20 , C07D493/04 , C07H1/00
摘要: A process for preparing a composition (C1) represented by the formula (I): HO—CH2—(CHOH)n—CH2—O-(G)x-H, in which G represents the remainder of a reducing sugar, n is an integer equal to 2, 3 or 4 and x, which indicates the mean degree of polymerization of the remainder G, represents a decimal number greater than 1 and less than or equal to 5, characterized in that the process includes at least one step a) of reacting a polyol of formula (A1): HO—CH2—(CHOH)n—CH2—OH, in which n is an integer equal to 2, 3 or 4, with a reducing sugar of formula (II): HO-G-H, in which G represents the remainder of a reducing sugar, in the presence of an acid catalyst (Ca), and in that the acid catalyst (Ca) is chosen from phosphorous acid, phosphoric acid and polyphosphoric acid.