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公开(公告)号：US09150445B2
公开(公告)日：2015-10-06
申请号：US13206327
申请日：2011-08-09
CPC分类号： C02F3/12 , C02F3/1221 , C02F3/1263 , C02F3/34 , C02F2209/001 , C02F2209/10 , C12P7/42 , C12P7/625 , Y02W10/15 , Y02W10/45
摘要： A wastewater treatment process elicits microorganisms to convert a waste stream/organic resource to intracellular biopolymer polyhydroxyalkanoate (PHA). The process includes (i) waste stream/organic resource composition feed criteria, (ii) configuration coupled with operational parameters, and (iii) PHA-laden biomass separation and stabilization. A waste stream/organic resource capable of producing enhanced levels of PHA may be selected based on a combination of criteria, which may include short chain fatty acid concentration, protein concentration, polysaccharides concentration, and total suspended solids concentration. The waste stream is introduced into an aeration basin upon a specific configuration and operated under various parameter combinations for selecting/enriching microorganisms capable of producing PHA. The PHA-laden biomass is separated and stabilized for downstream PHA related product beneficial uses. The present process achieves concurrent wastewater treatment and PHA production, where PHA level (of more than 10% on a cell-weight basis) otherwise could not be obtained.
摘要翻译： 废水处理过程引起微生物将废物流/有机物质转化为细胞内生物聚合物聚羟基链烷酸酯（PHA）。 该过程包括（i）废物流/有机资源组合物进料标准，（ii）配置与操作参数，以及（iii）含PHA的生物质分离和稳定化。 可以基于标准的组合来选择能够产生增强的PHA水平的废物流/有机资源，其可以包括短链脂肪酸浓度，蛋白质浓度，多糖浓度和总悬浮固体浓度。 废物流根据特定的构型被引入曝气池并在各种参数组合下操作，用于选择/富集能够生产PHA的微生物。 PHA负载生物质被分离并稳定下游PHA相关产品的有益用途。 本方法实现了同时进行的废水处理和PHA生产，其中PHA水平（以细胞重量计超过10％）不能获得。
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公开(公告)号：US20160023930A1
公开(公告)日：2016-01-28
申请号：US14875337
申请日：2015-10-05
CPC分类号： C02F3/12 , C02F3/1221 , C02F3/1263 , C02F3/34 , C02F2209/001 , C02F2209/10 , C12P7/42 , C12P7/625 , Y02W10/15 , Y02W10/45
摘要： A wastewater treatment process elicits microorganisms to convert a waste stream/organic resource to intracellular biopolymer polyhydroxyalkanoate (PHA). The process includes (i) waste stream/organic resource composition feed criteria, (ii) configuration coupled with operational parameters, and (iii) PHA-laden biomass separation and stabilization. A waste stream/organic resource capable of producing enhanced levels of PHA may be selected based on a combination of criteria, which may include short chain fatty acid concentration, protein concentration, polysaccharides concentration, and total suspended solids concentration. The waste stream is introduced into an aeration basin upon a specific configuration and operated under various parameter combinations for selecting/enriching microorganisms capable of producing PHA. The PHA-laden biomass is separated and stabilized for downstream PHA related product beneficial uses. The present process achieves concurrent wastewater treatment and PHA production, where PHA level (of more than 10% on a cell-weight basis) otherwise could not be obtained.
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公开(公告)号：US20130040351A1
公开(公告)日：2013-02-14
申请号：US13206327
申请日：2011-08-09
IPC分类号： C12P7/40
CPC分类号： C02F3/12 , C02F3/1221 , C02F3/1263 , C02F3/34 , C02F2209/001 , C02F2209/10 , C12P7/42 , C12P7/625 , Y02W10/15 , Y02W10/45
摘要： A wastewater treatment process elicits microorganisms to convert a waste stream/organic resource to intracellular biopolymer polyhydroxyalkanoate (PHA). The process includes (i) waste stream/organic resource composition feed criteria, (ii) configuration coupled with operational parameters, and (iii) PHA-laden biomass separation and stabilization. A waste stream/organic resource capable of producing enhanced levels of PHA may be selected based on a combination of criteria, which may include short chain fatty acid concentration, protein concentration, polysaccharides concentration, and total suspended solids concentration. The waste stream is introduced into an aeration basin upon a specific configuration and operated under various parameter combinations for selecting/enriching microorganisms capable of producing PHA. The PHA-laden biomass is separated and stabilized for downstream PHA related product beneficial uses. The present process achieves concurrent wastewater treatment and PHA production, where PHA level (of more than 10% on a cell-weight basis) otherwise could not be obtained.
摘要翻译： 废水处理过程引起微生物将废物流/有机物质转化为细胞内生物聚合物聚羟基链烷酸酯（PHA）。 该过程包括（i）废物流/有机资源组合物进料标准，（ii）配置与操作参数，以及（iii）含PHA的生物质分离和稳定化。 可以基于标准的组合来选择能够产生增强的PHA水平的废物流/有机资源，其可以包括短链脂肪酸浓度，蛋白质浓度，多糖浓度和总悬浮固体浓度。 废物流根据特定的构型被引入曝气池并在各种参数组合下操作，用于选择/富集能够生产PHA的微生物。 PHA负载生物质被分离并稳定下游PHA相关产品的有益用途。 本方法实现了同时进行的废水处理和PHA生产，其中PHA水平（以细胞重量计超过10％）不能获得。
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公开(公告)号：US10807893B2
公开(公告)日：2020-10-20
申请号：US15966978
申请日：2018-04-30
摘要： A wastewater treatment process elicits microorganisms to convert a waste stream/organic resource to intracellular biopolymer polyhydroxyalkanoate (PHA). The process includes (i) waste stream/organic resource composition feed criteria, (ii) configuration coupled with operational parameters, and (iii) PHA-laden biomass separation and stabilization. A waste stream/organic resource capable of producing enhanced levels of PHA may be selected based on a combination of criteria, which may include short chain fatty acid concentration, protein concentration, polysaccharides concentration, and total suspended solids concentration. The waste stream is introduced into an aeration basin or sequencing batch reactor upon a specific configuration and operated under various parameter combinations for selecting/enriching microorganisms capable of producing PHA. The PHA-laden biomass is separated and stabilized for downstream PHA related product beneficial uses. The present process achieves concurrent wastewater treatment and PHA production, where PHA level (of more than 10% on a cell-weight basis) otherwise could not be obtained.
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公开(公告)号：US20180273407A1
公开(公告)日：2018-09-27
申请号：US15966978
申请日：2018-04-30
摘要： A wastewater treatment process elicits microorganisms to convert a waste stream/organic resource to intracellular biopolymer polyhydroxyalkanoate (PHA). The process includes (i) waste stream/organic resource composition feed criteria, (ii) configuration coupled with operational parameters, and (iii) PHA-laden biomass separation and stabilization. A waste stream/organic resource capable of producing enhanced levels of PHA may be selected based on a combination of criteria, which may include short chain fatty acid concentration, protein concentration, polysaccharides concentration, and total suspended solids concentration. The waste stream is introduced into an aeration basin or sequencing batch reactor upon a specific configuration and operated under various parameter combinations for selecting/enriching microorganisms capable of producing PHA. The PHA-laden biomass is separated and stabilized for downstream PHA related product beneficial uses. The present process achieves concurrent wastewater treatment and PHA production, where PHA level (of more than 10% on a cell-weight basis) otherwise could not be obtained.
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公开(公告)号：US20090324685A1
公开(公告)日：2009-12-31
申请号：US12491434
申请日：2009-06-25
CPC分类号： A61L31/16 , A61L31/10 , A61L31/148 , A61L2300/114 , A61L2300/608
摘要： In accordance with certain aspects of the present invention, medical devices are provided which are configured for implantation or insertion into a subject. The medical devices include at least one coating region that comprises (a) a charged polyamino-acid-containing polymer having a first net charge and (b) an additional charged polymer having a second net charge that is opposite in sign to that of the first net charge. The additional charged polymer may or may not be a polyamino-acid-containing polymer.
摘要翻译： 根据本发明的某些方面，提供了被配置用于植入或插入到受试者中的医疗装置。 医疗装置包括至少一个涂层区域，其包含（a）具有第一净电荷的带电荷的含聚氨基酸的聚合物和（b）具有与第一净电荷相反的第二净电荷的附加带电聚合物 净费。 附加带电聚合物可以是或可以不是含聚氨基酸的聚合物。
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公开(公告)号：US20090297581A1
公开(公告)日：2009-12-03
申请号：US12472234
申请日：2009-05-26
IPC分类号： A61F2/06
CPC分类号： A61L31/16 , A61L31/08 , A61L2300/416 , A61L2300/606 , A61L2300/624 , A61L2420/04
摘要： According to one aspect, the present invention provides implantable or insertable medical devices that comprise a conductive substrate and an electrodeposited coating over the substrate. The electrodeposited coating includes (a) one or more types of inorganic materials, (b) one or more types of polymeric materials and (c) optionally, one or more types of therapeutic agents. Still other aspects of the invention concern methods of making and using such devices.
摘要翻译： 根据一个方面，本发明提供了可植入或可插入的医疗装置，其包括导电基底和在基底上的电沉积涂层。 电沉积涂层包括（a）一种或多种类型的无机材料，（b）一种或多种类型的聚合材料和（c）任选的一种或多种类型的治疗剂。 本发明的其它方面涉及制造和使用这些装置的方法。
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