公开(公告)号：US20160310564A1

公开(公告)日：2016-10-27

申请号：US15137281

申请日：2016-04-25

Applicant: Academia Sinica ,  National Taiwan Ocean University

Inventor： Jyh-Yih CHEN ,  Chang-Jer WU

IPC: A61K38/17

CPC classification number: A61K38/1706

Abstract: The preset invention relates to a new method for enhancing wound healing comprising administering a subject in need thereof with a therapeutically effective amount of a tilapia piscidin (TP), which is selected from the group consisting of TP1, TP2, TP3, TP4, TP5 and combination thereof. A composition or pharmaceutical composition comprising the TP are also provided.

Abstract translation: 本发明涉及一种用于增强伤口愈合的新方法，包括给予有需要的受试者治疗有效量的选自TP1，TP2，TP3，TP4，TP5和 的组合。 还提供了包含TP的组合物或药物组合物。

公开(公告)号：US20160303190A1

公开(公告)日：2016-10-20

申请号：US15098486

申请日：2016-04-14

Applicant: Academia Sinica ,  National Taiwan Ocean University

Inventor： Jyh-Yih CHEN ,  Chang-Jer WU

IPC: A61K38/17 ,  A61K45/06

CPC classification number: A61K38/1706

Abstract: The preset invention relates to a new method or composition for treating a gastric ulcer, preventing or treating an infection of H. pylori, particularly multidrug resistant H. pylori, using an antimicrobial peptide, a functional derivate, fragment or variant thereof, wherein the antimicrobial peptide is selected from the group consisting of Epi-1, TPs and combination thereof.

Abstract translation: 本发明涉及使用抗微生物肽，功能衍生物，片段或变体治疗胃溃疡，预防或治疗幽门螺杆菌感染特别是多药耐药性幽门螺杆菌的新方法或组合物，其中抗微生物剂 肽选自Epi-1，TP及其组合。

公开(公告)号：US20160082146A1

公开(公告)日：2016-03-24

申请号：US14857189

申请日：2015-09-17

Applicant: ACADEMIA SINICA

Inventor： Jyh-Yih CHEN ,  Chang-Jer WU ,  Han-Ning HUANG

IPC: A61L26/00 ,  A61L15/32 ,  A61L15/22 ,  A61L15/46

CPC classification number: A61L26/0047 ,  A61L15/32 ,  A61L15/325 ,  A61L15/46 ,  A61L26/0033 ,  A61L26/0066 ,  A61L2300/252 ,  A61L2300/404 ,  A61L2300/412

Abstract: The preset invention relates to a new method for wound healing, particularly in burns, comprising Epinecidin-1 (Epi-1) or Pardaxin (GE33), optionally in the incorporation into collagen.

Abstract translation: 本发明涉及一种新的伤口愈合方法，特别是在包含Epinecidin-1（Epi-1）或Pardaxin（GE33））的烧伤中，任选地并入胶原蛋白。