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公开(公告)号:US12053618B2
公开(公告)日:2024-08-06
申请号:US16761149
申请日:2018-11-06
Applicant: AMGEN INC.
Inventor: Justin Harris , Matthew Wayne Janke , Wael Mismar , Jerome Olivas , Thomas Clark Pearson , Sudeshna Dutta Ray , Ryan M. Agard , Alexis Dechelette , Michael Gammelager , Mads Hansen , Valerio Mazzon , Owen Ryan , Clive Smith
CPC classification number: A61M5/28 , A61M5/1782 , A61M5/24 , A61M5/3134 , A61M2005/2488 , A61M2005/3115
Abstract: Fill-finish assemblies facilitating the manufacture of a drug delivery device are disclosed. The fill-finish assembly may include a container, an insertion mechanism, a fluid pathway connection assembly disposed between the container and the insertion mechanism, and a carrier. The insertion mechanism may include a delivery member and an insertion mechanism housing. The insertion mechanism may be configured to move the delivery member from a retracted position inside the insertion mechanism housing to a deployed position outside the insertion mechanism housing. The fluid pathway connection assembly may be selectively activatable to establish fluid communication between the container and the delivery member. The carrier may have a hollow interior containing at least a portion of each of the container, the insertion mechanism, and the fluid pathway connection assembly. The carrier may be configured to hold the container, the insertion mechanism, and the fluid pathway connection assembly in alignment with each other.
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公开(公告)号:US20210330880A1
公开(公告)日:2021-10-28
申请号:US16625208
申请日:2018-07-11
Applicant: AMGEN INC.
Inventor: Sheldon Moberg , Matthew Wayne Janke , Wael Mismar , Alexis Dechelette
Abstract: Drug delivery devices and related methods of assembly are disclosed. The drug delivery device may include a container including a wall with an interior surface and a seal member with an end surface. The interior surface of the wall and the end surface of the seal member may define a reservoir filled with a drug. A fluid pathway assembly may be connected to the container and include an overmold member that covers a length of a container access needle and which defines an enclosed space with the seal member. The overmold member may be moveable relative to the seal member to carry the container access needle between a storage position, where a point of the container access needle is disposed exterior to the reservoir, and a delivery position, where the point extends through the end surface of the seal member into the reservoir.
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公开(公告)号:US20200338271A1
公开(公告)日:2020-10-29
申请号:US16761149
申请日:2018-11-06
Applicant: AMGEN INC.
Inventor: Justin Harris , Matthew Wayne Janke , Wael Mismar , Jerome Olivas , Thomas Clark Pearson , Sudeshna Dutta Ray , Ryan M. Agard , Alexis Dechelette , Michael Gammelager , Mads Hansen , Valerio Mazzon , Owen Ryan , Clive Smith
Abstract: Fill-finish assemblies facilitating the manufacture of a drug delivery device are disclosed. The fill-finish assembly may include a container, an insertion mechanism, a fluid pathway connection assembly disposed between the container and the insertion mechanism, and a carrier. The insertion mechanism may include a delivery member and an insertion mechanism housing. The insertion mechanism may be configured to move the delivery member from a retracted position inside the insertion mechanism housing to a deployed position outside the insertion mechanism housing. The fluid pathway connection assembly may be selectively activatable to establish fluid communication between the container and the delivery member. The carrier may have a hollow interior containing at least a portion of each of the container, the insertion mechanism, and the fluid pathway connection assembly. The carrier may be configured to hold the container, the insertion mechanism, and the fluid pathway connection assembly in alignment with each other.
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公开(公告)号:US20230043679A1
公开(公告)日:2023-02-09
申请号:US17960906
申请日:2022-10-06
Applicant: AMGEN INC.
Inventor: Sheldon Moberg , Matthew Wayne Janke , Wael Mismar , Alexis Dechelette
Abstract: Drug delivery devices and related methods of assembly are disclosed. The drug delivery device may include a container including a wall with an interior surface and a seal member with an end surface. The interior surface of the wall and the end surface of the seal member may define a reservoir filled with a drug. A fluid pathway assembly may be connected to the container and include an overmold member that covers a length of a container access needle and which defines an enclosed space with the seal member. The overmold member may be moveable relative to the seal member to carry the container access needle between a storage position, where a point of the container access needle is disposed exterior to the reservoir, and a delivery position, where the point extends through the end surface of the seal member into the reservoir.
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公开(公告)号:US11484648B2
公开(公告)日:2022-11-01
申请号:US16625208
申请日:2018-07-11
Applicant: AMGEN INC.
Inventor: Sheldon Moberg , Matthew Wayne Janke , Wael Mismar , Alexis Dechelette
Abstract: Drug delivery devices and related methods of assembly are disclosed. The drug delivery device may include a container including a wall with an interior surface and a seal member with an end surface. The interior surface of the wall and the end surface of the seal member may define a reservoir filled with a drug. A fluid pathway assembly may be connected to the container and include an overmold member that covers a length of a container access needle and which defines an enclosed space with the seal member. The overmold member may be moveable relative to the seal member to carry the container access needle between a storage position, where a point of the container access needle is disposed exterior to the reservoir, and a delivery position, where the point extends through the end surface of the seal member into the reservoir.
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