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公开(公告)号：US11904143B2
公开(公告)日：2024-02-20
申请号：US16609466
申请日：2018-06-04
Applicant: AMGEN INC.
Inventor： Adam B. McCullough , Ronald Forster , Joseph Michael Iglesias , Matias Melander , Rasmus Øhlenschlaeger , Christian Plambech , Lars Stenholt , Bjarke Lykke Ludvig Svendsen
CPC classification number: A61M5/3145 , A61M5/20 , A61M5/31583 , A61M2005/3143
Abstract: An injector includes a housing having a syringe assembly and an actuating mechanism at least partially disposed within the housing. The syringe assembly includes a syringe barrel that stores a medicament to be injected into a user, a needle assembly, and a filter member disposed adjacent to the needle assembly. The actuating mechanism is operatively coupled to the syringe assembly and includes a torque spring that exerts a torque to urge the medicament through the filter member to be injected into the user. The actuating mechanism further includes a damper mechanism that exerts an opposing force to dampen the motion exerted by the torque spring.
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公开(公告)号：US20240238529A1
公开(公告)日：2024-07-18
申请号：US18409480
申请日：2024-01-10
Applicant: AMGEN INC.
Inventor： Adam B. McCullough , Ronald Forster , Joseph Michael Iglesias , Matias Melander , Rasmus Øhlenschlæger , Christian Plambech , Lars Stenholt , Bjarke Lykke Ludvig Svendsen
CPC classification number: A61M5/3145 , A61M5/20 , A61M5/31583 , A61M2005/3143
Abstract: An injector includes a housing having a syringe assembly and an actuating mechanism at least partially disposed within the housing. The syringe assembly includes a syringe barrel that stores a medicament to be injected into a user, a needle assembly, and a filter member disposed adjacent to the needle assembly. The actuating mechanism is operatively coupled to the syringe assembly and includes a torque spring that exerts a torque to urge the medicament through the filter member to be injected into the user. The actuating mechanism further includes a damper mechanism that exerts an opposing force to dampen the motion exerted by the torque spring.
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公开(公告)号：US20230138654A1
公开(公告)日：2023-05-04
申请号：US16609466
申请日：2018-06-04
Applicant: AMGEN INC.
Inventor： Adam B. McCullough , Ronald Forster , Joseph Michael Iglesias , Matias Melander , Rasmus Øhelschlaeger , Christian Plambech , Lars Stenholt , Bjarke Lykke Ludvig Svendsen
Abstract: An injector includes a housing having a syringe assembly and an actuating mechanism at least partially disposed within the housing. The syringe assembly includes a syringe barrel that stores a medicament to be injected into a user, a needle assembly, and a filter member disposed adjacent to the needle assembly. The actuating mechanism is operatively coupled to the syringe assembly and includes a torque spring that exerts a torque to urge the medicament through the filter member to be injected into the user. The actuating mechanism further includes a damper mechanism that exerts an opposing force to dampen the motion exerted by the torque spring.
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公开(公告)号：US20210260302A1
公开(公告)日：2021-08-26
申请号：US17261648
申请日：2019-08-16
Applicant: AMGEN INC.
Inventor： Matias Melander , Joshua Jay Dudman , Joseph Michael Iglesias , Bjarke Lykke Ludvig Svendsen , Adam B. McCullough , Christian Plambech , Steve Sanchez
Abstract: A drug delivery device includes a housing, an injection assembly at least partially disposed in the housing, a shield, and a drive assembly at least partially disposed in the housing and coupled with the injection assembly and the shield. The shield has an extended position where at least a proximal end thereof extends a distance beyond a proximal end of the housing. The injection assembly includes a needle or cannula having an endpoint. Upon moving the shield axially towards the distal end of the housing a predetermined distance, a retraction profile commences whereby the drive assembly administers a medicament via the injection assembly. A peak resistance force is exerted within approximately the first 12 mm of axial movement of the shield.
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