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公开(公告)号：US20180263871A1
公开(公告)日：2018-09-20
申请号：US15760819
申请日：2016-09-23
Applicant: AMOREPACIFIC CORPORATION
Inventor： Suh-Yeon CHOI , Eun-Jeong CHOI , Bum-Ho BIN , Kyeonghwan HWANG , Eun-Gyung CHO , Tae Ryong LEE
IPC: A61K8/14 , A61Q19/02 , A61K8/9789
CPC classification number: A61K8/14 , A61K8/9789 , A61K36/258 , A61K2800/413 , A61Q19/02
Abstract: Disclosed are: a lightening composition comprising ginseng-derived exosome-like vesicles; and a method for producing the ginseng-derived exosome-like vesicles. The ginseng-derived exosome-like vesicles may have a diameter of between 20 and 500 nm, and may be isolated from ginseng root. Because the composition comprises the ginseng-derived exosome-like vesicles as an active ingredient, said composition is effective in preventing, improving or treating skin pigmentation conditions such as liver spots, freckles, lentigo, birth marks and melanoma by effectively suppressing the production of melanin.
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2.发明申请公开(公告)号：US20180177699A1
公开(公告)日：2018-06-28
申请号：US15739534
申请日：2016-06-15
Applicant: AMOREPACIFIC CORPORATION
Inventor： Bum-Ho BIN , Eun-Gyung CHO , Eun-Jeong CHOI , Sungtae KIM , Suhyeon CHOI , Taeryong LEE
CPC classification number: A61K8/494 , A61K8/49 , A61K8/4946 , A61K8/60 , A61K8/73 , A61K9/0014 , A61K9/0095 , A61K9/06 , A61K9/1652 , A61K9/205 , A61K9/4875 , A61K31/18 , A61K31/4178 , A61K47/06 , A61K47/10 , A61K47/14 , A61K47/22 , A61K47/42 , A61Q19/02 , G01N33/5044
Abstract: Disclosed in the present specification are: a skin whitening composition having a skin whitening effect by controlling the secretion of exosomes to be secreted from melanocytes; and a method for screening for materials having a skin whitening effect. The skin whitening composition can promote apoptosis of melanocytes by inhibiting the amount of secretion of exosomes to be secreted from melanocytes, and consequently inhibits the generation of melanin through the apoptosis of melanocytes, thereby exhibiting a skin whitening effect.
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