公开(公告)号：US11938163B2

公开(公告)日：2024-03-26

申请号：US17341868

申请日：2021-06-08

Applicant: AMOREPACIFIC CORPORATION

Inventor： Hyunjin Nam ,  Juewon Kim ,  Miyoung Park ,  Kyoungmi Jung ,  Jinoh Chung ,  Gyeyoung Choi ,  Wanki Kim

IPC: A61K36/82 ,  A23L2/52 ,  A23L33/00 ,  A23L33/105 ,  A61K9/00 ,  A61K31/353 ,  A61P7/00 ,  A61P11/16

CPC classification number: A61K36/82 ,  A23L2/52 ,  A23L33/105 ,  A23L33/40 ,  A61K9/0056 ,  A61K31/353 ,  A61P7/00 ,  A61P11/16 ,  A23V2002/00 ,  A61K2236/33 ,  A61K2236/331 ,  A61K2236/333

Abstract: An aspect of the present disclosure relates to a composition for improving respiratory health exposed to particulate matter, which contains a green tea extract, a green tea polysaccharide and a green tea flavonol as active ingredients. The composition provided in an aspect of the present disclosure can improve respiratory health damaged by exposure to particulate matter by enhancing the effect of preventing adsorption of particulate matter to bronchial epithelial cells and activating the cilia of bronchial epithelial cells. The composition provided in an aspect of the present disclosure may decrease blood heavy metal level.

公开(公告)号：US11878008B2

公开(公告)日：2024-01-23

申请号：US16805381

申请日：2020-02-28

Applicant: AMOREPACIFIC CORPORATION

Inventor： Gyeyoung Choi ,  Hyunjin Nam ,  Miyoung Park ,  Kyoungmi Jung ,  Jihae Lee ,  Chang Soon Choi ,  Youngho Park ,  Jong Hwa Roh ,  Eunsil Park ,  Jaehong Park ,  Kwanghyun Shin ,  Byoung Young Woo ,  Kiwha Lee ,  Wonkyung Cho ,  Joonho Choi

IPC: A61P17/04 ,  A61K31/44 ,  A61K9/00

CPC classification number: A61K31/44 ,  A61K9/0014 ,  A61P17/04

Abstract: Disclosed is a method for preventing or treating atopic dermatitis using TRPV1 receptor antagonist. More specifically, it may be possible to prevent and/or treat the atopic dermatitis without any side effects such as an increase in body temperature, epidermal atrophy, and the like by percutaneously administrating a composition for external use on the skin containing the TRPV1 receptor antagonist.

公开(公告)号：US11382900B2

公开(公告)日：2022-07-12

申请号：US16805202

申请日：2020-02-28

Applicant: AMOREPACIFIC CORPORATION

Inventor： Gyeyoung Choi ,  Hyunjin Nam ,  Miyoung Park ,  Kyoungmi Jung ,  Jihae Lee ,  Chang Soon Choi ,  Youngho Park ,  Jong Hwa Roh ,  Eunsil Park ,  Jaehong Park ,  Kwanghyun Shin ,  Byoung Young Woo ,  Kiwha Lee ,  Wonkyung Cho ,  Joonho Choi

IPC: A61K31/44 ,  A61K9/00 ,  A61K9/06

Abstract: Disclosed is a method for preventing or treating sleep disorders using TRPV1 receptor antagonist, (R)—N-[1-(3,5-difluoro-4-methanesulfonylamino-phenyl)-ethyl]-3-(2-propyl-6-trifluoromethyl-pyridin-3-yl)-acrylamide. The method of the present invention can effectively and safely prevent or treat sleep disorders accompanying pruritus caused by atopic dermatitis.

公开(公告)号：US10479763B2

公开(公告)日：2019-11-19

申请号：US15325349

申请日：2016-02-15

Applicant: AMOREPACIFIC CORPORATION

Inventor： Byoung Young Woo ,  Ki-Wha Lee ,  Kwang-Hyun Shin ,  Miyoung Park ,  Kyoungmi Jung ,  Joonho Choi ,  Gyeyoung Choi ,  Wonkyung Cho ,  Young-Ho Park

IPC: C07C303/42 ,  C07C303/36 ,  C07C311/08 ,  C07C303/44 ,  C07D213/56 ,  C07B57/00 ,  C07C63/06

Abstract: The present specification relates to a chiral resolution method of a stereoisomer mixture, comprising a step of mixing a stereoisomer mixture of compounds, in which an amine group is bound to an asymmetric carbon atom, with a chiral auxiliary and salt-forming auxiliary compound, wherein the chiral auxiliary is an O,O′-diacyltartaric acid derivative, more specifically, a 2,3-dibenzoyl-tartaric acid or O,O′-di-p-toluoyl tartaric acid, the salt-forming auxiliary compound is mandelic acid or camphorsulfonic acid, and an optical isomer having a high level of optical purity can be obtained by using the method. Therefore, according to one aspect of the present invention, the method can be useful in pharmaceutical or cosmetic field when preparing an optical isomer having a high optical purity.