公开(公告)号：US20180263871A1

公开(公告)日：2018-09-20

申请号：US15760819

申请日：2016-09-23

Applicant: AMOREPACIFIC CORPORATION

Inventor： Suh-Yeon CHOI ,  Eun-Jeong CHOI ,  Bum-Ho BIN ,  Kyeonghwan HWANG ,  Eun-Gyung CHO ,  Tae Ryong LEE

IPC: A61K8/14 ,  A61Q19/02 ,  A61K8/9789

CPC classification number: A61K8/14 ,  A61K8/9789 ,  A61K36/258 ,  A61K2800/413 ,  A61Q19/02

Abstract: Disclosed are: a lightening composition comprising ginseng-derived exosome-like vesicles; and a method for producing the ginseng-derived exosome-like vesicles. The ginseng-derived exosome-like vesicles may have a diameter of between 20 and 500 nm, and may be isolated from ginseng root. Because the composition comprises the ginseng-derived exosome-like vesicles as an active ingredient, said composition is effective in preventing, improving or treating skin pigmentation conditions such as liver spots, freckles, lentigo, birth marks and melanoma by effectively suppressing the production of melanin.

公开(公告)号：US20190041383A1

公开(公告)日：2019-02-07

申请号：US15764615

申请日：2016-09-29

Applicant: AMOREPACIFIC CORPORATION

Inventor： Suh-Yeon CHOI ,  Eunkyung LEE ,  Eun-Gyung CHO ,  Tae Ryong LEE

IPC: G01N33/50 ,  C12N5/071 ,  C12N13/00

Abstract: Disclosed in the present specification are a method for preparing senescent melanocytes, senescent cells prepared by the preparation method and a method for screening a senescence-alleviating or skin whitening material by using the senescent cells. The cells can be used for studying a cell senescence phenomenon and a pigmentation mechanism, which are caused by the accumulation of UV ray stimulation. Particularly, the cells are useful since a material having both senescence-alleviating and skin whitening effects can be screened.