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公开(公告)号：US11592016B2
公开(公告)日：2023-02-28
申请号：US16928980
申请日：2020-07-14
Inventor： Michael N. Kozicki , Junseok Chae
Abstract: A low-voltage microfluidic valve device and system for regulating the flow of fluid. One low-voltage microfluidic valve device for regulating the low of fluid includes a nano-textured dendritic metallic filament configured to grow and retract in response to a voltage. The low-voltage microfluidic valve device also includes a microfluidic channel configured to allow fluid flow, wherein the fluid flow is selectively interrupted by the growth of the nano-textured dendritic metallic filament. The low-voltage microfluidic valve device also includes a membrane positioned proximate to the fluid and configured to alter shape in response to the growth of the nano-textured dendritic metallic filament.
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公开(公告)号：US10710070B2
公开(公告)日：2020-07-14
申请号：US15774440
申请日：2016-11-22
Inventor： Michael N. Kozicki , Junseok Chae
Abstract: A low-voltage microfluidic valve device and system for regulating the flow of fluid. One low-voltage microfluidic valve device for regulating the low of fluid includes a nano-textured dendritic metallic filament configured to grow and retract in response to a voltage. The low-voltage microfluidic valve device also includes a microfluidic channel configured to allow fluid flow, wherein the fluid flow is selectively interrupted by the growth of the nano-textured dendritic metallic filament. The low-voltage microfluidic valve device also includes a membrane positioned proximate to the fluid and configured to alter shape in response to the growth of the nano-textured dendritic metallic filament.
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公开(公告)号：US20190291107A1
公开(公告)日：2019-09-26
申请号：US15774440
申请日：2016-11-22
Inventor： Michael N. Kozicki , Junseok Chae
Abstract: A low-voltage microfluidic valve device and system for regulating the flow of fluid. One low-voltage microfluidic valve device for regulating the low of fluid includes a nano-textured dendritic metallic filament configured to grow and retract in response to a voltage. The low-voltage microfluidic valve device also includes a microfluidic channel configured to allow fluid flow, wherein the fluid flow is selectively interrupted by the growth of the nano-textured dendritic metallic filament. The low-voltage microfluidic valve device also includes a membrane positioned proximate to the fluid and configured to alter shape in response to the growth of the nano-textured dendritic metallic filament.
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公开(公告)号：US10119960B2
公开(公告)日：2018-11-06
申请号：US15316710
申请日：2015-06-09
Inventor： Junseok Chae , Jennie Appel , Joseph Liao
IPC: G01N33/50 , G01N21/84 , G01N33/487 , G01N33/574
Abstract: Systems and methods for performing cancer screening assays are disclosed. The disclosed systems and methods use a thin film comprising cross-linked polysiloxane. At least a portion of a biological sample to be assayed is contacted with the thin film, along with a cell culture media. After a subsequent incubation period, the thin film is visualized to detect a wrinkle pattern (or lack thereof). The presence of one or more wrinkles and/or a higher degree of wrinkling in the thin film indicates the presence of cancer cells in the biological sample. The disclosed systems and methods can be incorporated into improved assays and kits for cancer screening.
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公开(公告)号：US11428588B2
公开(公告)日：2022-08-30
申请号：US16834726
申请日：2020-03-30
Inventor： Shiyi Liu , Junseok Chae
Abstract: Fully-passive sensor systems that receive an input electromagnetic signal and return an output electromagnetic signal are described. The sensor systems can be used to measure pressure in biological or non-biological systems.
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Patent Agency Ranking
公开(公告)号：US20170191989A1
公开(公告)日：2017-07-06
申请号：US15316710
申请日：2015-06-09
Inventor： Junseok Chae , Jennie Appel , Joseph Liao
IPC: G01N33/50 , G01N21/84 , G01N33/487
CPC classification number: G01N33/5091 , G01N21/8422 , G01N33/487 , G01N33/574
Abstract: Systems and methods for performing cancer screening assays are disclosed. The disclosed systems and methods use a thin film comprising cross-linked polysiloxane. At least a portion of a biological sample to be assayed is contacted with the thin film, along with a cell culture media. After a subsequent incubation period, the thin film is visualized to detect a wrinkle pattern (or lack thereof). The presence of one or more wrinkles and/or a higher degree of wrinkling in the thin film indicates the presence of cancer cells in the biological sample. The disclosed systems and methods can be incorporated into improved assays and kits for cancer screening.
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公开(公告)号：US11696713B2
公开(公告)日：2023-07-11
申请号：US16809778
申请日：2020-03-05
Applicant: Arizona Board of Regents on behalf of Arizona State University , Mayo Foundation for Medical Education and Research
Inventor： Junseok Chae , Shiyi Liu , Alfredo Quinones-Hinojosa , Tito Vivas-Buitrago
CPC classification number: A61B5/24 , A61B5/0031 , A61B5/6868 , A61B2562/046
Abstract: ElectroCorticoGraphy (ECoG) sensors and uses are disclosed. These ECoG arrays, systems, and processes may be operable or configured to: i) simultaneously record neural signals while providing stimulation on specific portions of the cortex using a user-guided stimulator; ii) acquire neural signals over a large cortex area; iii) provide individual or group stimulation while concurrently receiving neural feedback; and/or iv) acquire neural signals at a setting remote from the neural source using wireless or other communication techniques.
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公开(公告)号：US20200253578A1
公开(公告)日：2020-08-13
申请号：US16783579
申请日：2020-02-06
Inventor： Junseok Chae , Ang Chen
Abstract: The disclosure relates to processes, articles of manufacture, devices, and systems involving biomedical monitoring measurement and analysis. More particularly, respiratory measurement, monitoring, analysis, or related systems involving wearable sensors and receiving monitors for respiratory behavior tracking and analysis.
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公开(公告)号：US20230293074A1
公开(公告)日：2023-09-21
申请号：US18322109
申请日：2023-05-23
Applicant: Arizona Board of Regents on behalf of Arizona State University , Mayo Foundation for Medical Education and Research
Inventor： Junseok Chae , Shiyi Liu , Alfredo Quinones-Hinojosa , Tito Vivas-Buitrago
CPC classification number: A61B5/24 , A61B5/0031 , A61B5/6868 , A61B2562/046
Abstract: ElectroCorticoGraphy (ECoG) sensors and uses are disclosed. These ECoG arrays, systems, and processes may be operable or configured to: i) simultaneously record neural signals while providing stimulation on specific portions of the cortex using a user-guided stimulator; ii) acquire neural signals over a large cortex area; iii) provide individual or group stimulation while concurrently receiving neural feedback; and/or iv) acquire neural signals at a setting remote from the neural source using wireless or other communication techniques.
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公开(公告)号：US11266840B2
公开(公告)日：2022-03-08
申请号：US16453581
申请日：2019-06-26
Inventor： Junseok Chae
Abstract: Systems, devices, and methods involving cardiac pace making are provided. Implantable wireless pace making systems, devices, and methods using electromagnetic waveforms to interact with subcutaneous implanted sensors or stimulators, or both, are described. Systems, devices, and methods can include wireless, miniaturized, battery-free, radiofrequency (RF) microwave activated, sensors or stimulators or integrated sensor/stimulators that are implanted in multiple thoracic cavity locations, and interact with a remote pace making control-module or multiple modules.
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