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公开(公告)号：US20100041045A1
公开(公告)日：2010-02-18
申请号：US12502439
申请日：2009-07-14
申请人： Alexander Rueck , Bernhard Schoenenberger , Sergiy Yarmoluk , Vladyslava Kovalska , Mykhaylo Losytskyy , Yurii Slominskii
发明人： Alexander Rueck , Bernhard Schoenenberger , Sergiy Yarmoluk , Vladyslava Kovalska , Mykhaylo Losytskyy , Yurii Slominskii
CPC分类号： C07D417/06 , C09B23/04 , C09B23/06 , C09B23/083 , C09B23/086 , G01N1/30 , G01N21/6428
摘要： The present invention provides fluorescent dye compounds and methods of using the compounds for the staining of nucleic acids including qPCR applications. In particular, the dye compounds comprise heterocyclic molecules with hydroxy alkyl and aromatic substituents, and the dye compounds form highly fluorescent complexes upon nucleic acid binding.
摘要翻译： 本发明提供荧光染料化合物和使用该化合物染色包括qPCR应用在内的核酸的方法。 特别地，染料化合物包含具有羟基烷基和芳族取代基的杂环分子，并且染料化合物在核酸结合时形成高度荧光复合物。
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公开(公告)号：US20060207881A1
公开(公告)日：2006-09-21
申请号：US11344802
申请日：2006-02-01
申请人： Vladyslava Kovalska , Dmytro Kryvorotenko , Mykhaylo Losytskyy , Pierre Nording , Alexander Rueck , Bernhard Schoenenberger , Sergiy Yarmoluk , Fabian Wahl
发明人： Vladyslava Kovalska , Dmytro Kryvorotenko , Mykhaylo Losytskyy , Pierre Nording , Alexander Rueck , Bernhard Schoenenberger , Sergiy Yarmoluk , Fabian Wahl
CPC分类号： C09B23/06 , C09B23/0008 , C09B23/12 , G01N27/44726
摘要： The present invention is generally directed to a method for detecting polyamino acids. More specifically, the present invention is directed to a method for detecting polyamino acids using trimethincyanine dyes that interact non-covalently with polyamino acids to produce an optically detectable dye/polyamino acid complex.
摘要翻译： 本发明一般涉及一种检测聚氨基酸的方法。 更具体地，本发明涉及使用与聚氨基酸非共价相互作用以产生可光学检测的染料/聚氨基酸复合物的三聚甲硫氨酸染料检测聚氨基酸的方法。
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公开(公告)号：US20090131279A1
公开(公告)日：2009-05-21
申请号：US11940879
申请日：2007-11-15
IPC分类号： C40B50/06 , C07D215/00 , C07H21/00 , G01N31/00
CPC分类号： C09B23/04 , C07D417/06 , C09B23/02 , G01N1/30 , Y10T436/107497
摘要： The present invention provides fluorescent dye compounds and methods of using the compounds for the staining of nucleic acids. In particular, the dye compounds comprise heterocyclic molecules with hydroxy alkyl and aromatic substituents, and the dye compounds form highly fluorescent complexes upon nucleic acid binding.
摘要翻译： 本发明提供荧光染料化合物和使用该化合物染色核酸的方法。 特别地，染料化合物包含具有羟基烷基和芳族取代基的杂环分子，并且染料化合物在核酸结合时形成高度荧光复合物。
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公开(公告)号：US20100014166A1
公开(公告)日：2010-01-21
申请号：US12488811
申请日：2009-06-22
IPC分类号： G02B27/01
CPC分类号： G02B23/10 , F41G3/02 , F41G3/06 , G01C3/04 , G02B27/0101 , G02B27/1066 , G02B27/143 , G02B27/144 , G02B2027/0118
摘要： An observation device includes at least one day vision channel, an information channel with a graphic electronic display for producing a display image and a combination optical system for combining the day vision channel and the information channel, so that a combined overall image forms.
摘要翻译： 观察装置包括至少一天视力通道，具有用于产生显示图像的图形电子显示器的信息通道和用于组合日视频通道和信息通道的组合光学系统，从而形成组合的整体图像。
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公开(公告)号：US07978415B2
公开(公告)日：2011-07-12
申请号：US12488811
申请日：2009-06-22
CPC分类号： G02B23/10 , F41G3/02 , F41G3/06 , G01C3/04 , G02B27/0101 , G02B27/1066 , G02B27/143 , G02B27/144 , G02B2027/0118
摘要： An observation device includes at least one day vision channel, an information channel with a graphic electronic display for producing a display image and a combination optical system for combining the day vision channel and the information channel, so that a combined overall image forms.
摘要翻译： 观察装置包括至少一天视力通道，具有用于产生显示图像的图形电子显示器的信息通道和用于组合日视觉通道和信息通道的组合光学系统，从而形成组合的整体图像。
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公开(公告)号：US20060214112A1
公开(公告)日：2006-09-28
申请号：US11223202
申请日：2005-09-09
申请人： Ute Resch-Genger , Dietmar Pfeifer , Christian Monte , Angelika Hoffmann , Pierre Nording , Bernhard Schoenenberger , Katrin Hoffmann , Monika Spieles , Knut Rurack
发明人： Ute Resch-Genger , Dietmar Pfeifer , Christian Monte , Angelika Hoffmann , Pierre Nording , Bernhard Schoenenberger , Katrin Hoffmann , Monika Spieles , Knut Rurack
CPC分类号： G01N21/278 , G01N21/64 , G01N2021/6417 , Y10T436/10 , Y10T436/108331
摘要： The invention is directed to a method and a kit for calibrating a photoluminescence measurement system, in particular a fluorescence measurement system. The kit includes a number of fluorescence standards i and their corrected and certified fluorescence spectra Ii(λ), whereby the fluorescence standards i are selected, so that their spectrally corrected fluorescence spectra Ii(λ) cover a broad spectral range with high intensity. The standards are characterized by large half-widths FWHMi of their bands of at least 1400 cm−1. According to the method of the invention, partial correction functions Fi(λ) are generated by forming the quotient of the measured fluorescence spectra Ji(λ) and the corresponding corrected fluorescence spectra Ii(λ), which are then combined to form a total correction function F(λ) for a broad spectral range. The combination factors αi are hereby computed by statistical averaging of consecutive partial correction functions Fi(λ) over only a predefined, limited overlap region λi/i+1±ΔλOL about the mutual crossover wavelength λi/i+1.
摘要翻译： 本发明涉及用于校准光致发光测量系统，特别是荧光测量系统的方法和试剂盒。 该试剂盒包括许多荧光标准品i及其校准和认证的荧光光谱Iλ（λ），由此选择荧光标准品i，使得它们的光谱校正的荧光光谱I i < / SUB（λ）覆盖了具有高强度的宽光谱范围。 这些标准的特征在于它们的至少1400cm -1的波段的大半宽度FWHMi 。 根据本发明的方法，通过形成所测量的荧光光谱λ（λ）的商和对应的校正函数来产生部分校正函数F（λ） 荧光光谱I（λ），然后将其组合以形成宽光谱范围的总校正函数F（λ）。 因此，通过仅在预定义的有限重叠区域λi / i上的连续部分校正函数F（i）的统计平均来计算组合因子αi i i 关于相互交叉波长λ1/ i + 1的+1 + / / / / -
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