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    Cosmetic method for treatment of skin
    2.
    发明授权
    Cosmetic method for treatment of skin 失效
    化妆品治疗皮肤的方法

    公开(公告)号：US5382432A

    公开(公告)日：1995-01-17

    申请号：US152151

    申请日：1993-11-15

    申请人： John P. McCook ,  Alan J. Meyers ,  Anthony Vargas

    发明人： John P. McCook ,  Alan J. Meyers ,  Anthony Vargas

    IPC分类号： A61K8/30 ,  A61K20060101 ,  A61K8/00 ,  A61K8/33 ,  A61K8/36 ,  A61K8/365 ,  A61K8/368 ,  A61K31/19 ,  A61K31/20 ,  A61P17/00 ,  A61Q19/00 ,  A61K7/48

    CPC分类号： A61Q19/00 ,  A61K8/365 ,  A61K8/368 ,  A61K2800/75 ,  Y10S514/844 ,  Y10S514/847

    摘要： A method is provided for improving skin condition through a system whose steps include applying to the skin separately on a plurality of days a first composition that incorporates a C.sub.2 -C.sub.28 .alpha.- or .beta.-hydroxy carboxylic acid in a pharmaceutically acceptable carrier. Once the skin has acclimated to any irritation induced by the first composition, a second composition is applied to the skin daily for a subsequent period of time. The second composition will also include hydroxy carboxylic acid but at a level at least about 10% higher than that employed in the first composition. Once the skin has acclimated to the second composition, subsequent progressive increases of the active hydroxy carboxylic acid can be applied over subsequent periods of time Finally, a maintenance level composition is utilized with the highest level of hydroxy carboxylic acid in the progressive program to minimize potential irritation.

    摘要翻译： 提供了一种通过系统改善皮肤状况的方法，该系统的步骤包括在多天内单独施用包含C2-C28α-或β-羟基羧酸的药物可接受的载体中的第一组合物。 一旦皮肤适应于由第一组合物引起的任何刺激，将第二组合物每天施用于皮肤随后一段时间。 第二组合物还将包括羟基羧酸，但其含量比第一组合物中使用的水平高至少约10％。 一旦皮肤适应于第二种组合物，随后的活性羟基羧酸的逐渐增加可以在随后的时间段内施用。最后，在渐进程序中使用最高水平的羟基羧酸的维持水平组合物以最小化潜力 刺激。

    Cosmetic method for treatment of skin
    3.
    发明授权
    Cosmetic method for treatment of skin 失效
    化妆品治疗皮肤的方法

    公开(公告)号：US5401517A

    公开(公告)日：1995-03-28

    申请号：US153015

    申请日：1993-11-15

    申请人： Alan J. Meyers ,  Alan Evenson ,  Peter Dorogi ,  John P. McCook

    发明人： Alan J. Meyers ,  Alan Evenson ,  Peter Dorogi ,  John P. McCook

    IPC分类号： A61K8/00 ,  A61K8/67 ,  A61K31/07 ,  A61P17/00 ,  A61Q19/00 ,  A61K7/48

    CPC分类号： A61Q19/00 ,  A61K8/671 ,  A61K2800/75 ,  A61K2800/884 ,  Y10S514/828 ,  Y10S514/844 ,  Y10S514/846 ,  Y10S514/847

    摘要： A method is provided for improving skin condition through a system whose steps include applying to the skin separately on a plurality of days a first composition that incorporates a retinoid which is either retinol or retinoic acid in a pharmaceutically acceptable carrier. Once the skin has acclimated to any irritation induced by the first composition, a second composition is applied to the skin daily for a subsequent period of time. The second composition will also include retinoid but at a level at least about 10% higher than that employed in the first composition. Once the skin has acclimated to the second composition, subsequent progressive increases of the active retinoid can be applied over subsequent periods of time. Finally, a maintenance level composition is utilized with the highest level of retinoid in the progressive program to minimize potential irritation.

    摘要翻译： 提供了一种通过系统改善皮肤状况的方法，该系统的步骤包括在多天内分别施用第一种组合物，该第一组合物在药学上可接受的载体中掺入视黄醇或视黄酸。 一旦皮肤适应于由第一组合物引起的任何刺激，将第二组合物每天施用于皮肤随后的一段时间。 第二组合物还将包括类视黄醇，但其含量比第一组合物中使用的水平高至少约10％。 一旦皮肤适应第二种组合物，随后的活性类视色素的随后逐渐增加可以在随后的时间段内施用。 最后，维持级别组合物被用于渐进方案中最高水平的类视黄醇，以尽量减少潜在的刺激。