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公开(公告)号:US08486397B2
公开(公告)日:2013-07-16
申请号:US12882330
申请日:2010-09-15
申请人: Anil D. Bagri , Germaine Fuh , Chingwei V. Lee
发明人: Anil D. Bagri , Germaine Fuh , Chingwei V. Lee
IPC分类号: A61K39/395
CPC分类号: C07K16/22 , A61K39/3955 , A61K2039/505 , A61K2039/507 , C07K2317/24 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2319/30 , C07K2319/32 , A61K2300/00
摘要: The invention provides VEGF-C antagonists, such as anti-VEGF-C antibodies, and their use in the prevention and treatment of tumor progression.
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公开(公告)号:US20120052566A9
公开(公告)日:2012-03-01
申请号:US12882330
申请日:2010-09-15
申请人: Anil D. Bagri , Germaine Fuh , Chingwei V. Lee
发明人: Anil D. Bagri , Germaine Fuh , Chingwei V. Lee
CPC分类号: C07K16/22 , A61K39/3955 , A61K2039/505 , A61K2039/507 , C07K2317/24 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2319/30 , C07K2319/32 , A61K2300/00
摘要: The invention provides VEGF-C antagonists, such as anti-VEGF-C antibodies, and their use in the prevention and treatment of tumor progression.
摘要翻译: 本发明提供VEGF-C拮抗剂,例如抗VEGF-C抗体,以及它们在预防和治疗肿瘤进展中的用途。
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公开(公告)号:US20110143428A1
公开(公告)日:2011-06-16
申请号:US12882330
申请日:2010-09-15
申请人: Anil D. Bagri , Germaine Fuh , Chingwei V. Lee
发明人: Anil D. Bagri , Germaine Fuh , Chingwei V. Lee
CPC分类号: C07K16/22 , A61K39/3955 , A61K2039/505 , A61K2039/507 , C07K2317/24 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/73 , C07K2317/76 , C07K2317/92 , C07K2319/30 , C07K2319/32 , A61K2300/00
摘要: The invention provides VEGF-C antagonists, such as anti-VEGF-C antibodies, and their use in the prevention and treatment of tumor progression.
摘要翻译: 本发明提供VEGF-C拮抗剂,例如抗VEGF-C抗体,以及它们在预防和治疗肿瘤进展中的用途。
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公开(公告)号:US20100221262A1
公开(公告)日:2010-09-02
申请号:US12622345
申请日:2009-11-19
申请人: Alexander W. Koch , Ryan J. Watts , Yan Wu , Anil D. Bagri
发明人: Alexander W. Koch , Ryan J. Watts , Yan Wu , Anil D. Bagri
IPC分类号: A61K39/395 , C07K16/00 , C12N15/13 , C12N15/63 , C12N1/00 , C12N5/00 , C12P21/00 , A61K31/7052 , G01N33/53 , A61P35/00 , A61P9/10
CPC分类号: C07K16/2803 , A61K2039/505 , C07K2317/21 , C07K2317/56 , C07K2317/565 , C07K2317/76 , C07K2317/92
摘要: The invention provides anti-Unc5B antibodies, compositions and kits comprising the antibodies and methods of making and using the antibodies. The present invention also relates to use of anti-Unc5B antibodies to modulate angiogenesis and to treat or prevent disorders associated with abnormal angiogenesis.
摘要翻译: 本发明提供抗Unc5B抗体,包含抗体的组合物和试剂盒以及制备和使用抗体的方法。 本发明还涉及抗Unc5B抗体调节血管生成并治疗或预防与异常血管生成相关的病症的用途。
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5.METHOD TO IDENTIFY A PATIENT WITH AN INCREASED LIKELIHOOD OF RESPONDING TO AN ANTI-CANCER AGENT 审中-公开
标题翻译: 识别患有抗癌药物的增加症状的患者的方法公开(公告)号:US20110064670A1
公开(公告)日:2011-03-17
申请号:US12879234
申请日:2010-09-10
CPC分类号: A61K49/0054 , G01N2800/52
摘要: The invention provides methods for identifying patients having an increased likelihood of responding to an anti-cancer agent or an increased likelihood of undergoing metastasis. The invention also provides methods for monitoring a patients' response to an anti-cancer agent. The invention also provides kits and articles of manufacture for use in the methods.
摘要翻译: 本发明提供了用于鉴定具有增加的抗癌药物应答可能性或增加转移可能性的患者的方法。 本发明还提供了用于监测患者对抗癌剂的反应的方法。 本发明还提供用于该方法的试剂盒和制品。
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公开(公告)号:US20100029491A1
公开(公告)日:2010-02-04
申请号:US12499692
申请日:2009-07-08
申请人: Maike Schmidt , Anil D. Bagri
发明人: Maike Schmidt , Anil D. Bagri
CPC分类号: C12Q1/6886 , C12Q2600/106
摘要: Diagnostic markers for tumors, and their use in the diagnosis and treatment of tumors are provided.
摘要翻译: 提供肿瘤的诊断标志物及其在肿瘤诊断和治疗中的应用。
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