公开(公告)号：US20220213447A1

公开(公告)日：2022-07-07

申请号：US17613427

申请日：2020-05-22

Applicant: Avitide LLC

Inventor： William Scott Dodson ,  Brandon Kier ,  Brandon Coyle ,  Sarah Valentini ,  Thomas Scanlon ,  Warren Kett

IPC: C12N7/00 ,  C07K7/02 ,  C07K7/06 ,  C07K7/08 ,  B01D15/32 ,  B01D15/38

Abstract: Provided herein are affinity agents comprising ligands that specifically bind adeno-associated virus. The affinity agents are useful for binding, isolation, and/or purification of adeno-associated virus. Further disclosed are amino acid sequences of binding motifs or polypeptides comprised by the ligands, and associated modifications of the binding motifs and/or polypeptides, as well as a method of making the affinity agents.

公开(公告)号：US20240174717A1

公开(公告)日：2024-05-30

申请号：US18281147

申请日：2022-03-10

Applicant: Avitide LLC

Inventor： William Scott Dodson ,  Ethan Dow ,  Yi Zhang ,  Brandon Coyle ,  Kelley Kearns ,  Warren Kett

IPC: C07K7/56 ,  B01J20/32

CPC classification number: C07K7/56 ,  B01J20/3219 ,  B01J20/3274

Abstract: Provided herein are affinity agents comprising ligands that specifically bind target molecules. The affinity agents are useful for binding, isolation, and/or purifications.

公开(公告)号：US20230391829A1

公开(公告)日：2023-12-07

申请号：US18031833

申请日：2021-10-13

Applicant: Avitide LLC

Inventor： Sarmistha Bhattacharya ,  Brandon Coyle ,  Sarah Valentini ,  Kelley Kearns ,  Thomas Scanlon ,  William Wellborn ,  Warren Kett

IPC: C07K14/00 ,  C07K1/22 ,  B01D15/38

CPC classification number: C07K14/001 ,  C07K2319/21 ,  B01D15/3804 ,  C07K1/22

Abstract: Provided herein are affinity ligands that specifically interact with AAV8 capsid and/or AAV8 variant capsid, affinity agents comprising the affinity ligands, and methods of their use for binding, isolation, and/or purification of AAV8 and variants thereof.