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    Production Of Inorganic-Organic Composite Materials By Reactive Spray-Drying
    1.
    发明申请
    Production Of Inorganic-Organic Composite Materials By Reactive Spray-Drying 审中-公开
    通过反应性喷雾干燥生产无机 - 有机复合材料

    公开(公告)号：US20150342887A1

    公开(公告)日：2015-12-03

    申请号：US14824207

    申请日：2015-08-12

    Applicant: BASF SE

    Inventor： Andreas Kempter ,  Max Siebert ,  Heidrun Debus

    IPC: A61K9/16 ,  A61K31/415 ,  A61K31/496 ,  A61K31/192 ,  A61K31/58 ,  A61K31/565

    CPC classification number: A61K9/1682 ,  A61J3/005 ,  A61J3/02 ,  A61K9/143 ,  A61K9/145 ,  A61K9/1611 ,  A61K9/1617 ,  A61K31/192 ,  A61K31/415 ,  A61K31/496 ,  A61K31/565 ,  A61K31/58 ,  B01D1/18 ,  B01J2/04

    Abstract: A composite material comprising at least one amorphous hydrophobic active ingredient in an amorphous salt matrix with a solubility in the neutral aqueous medium of less than 0.02 mol/l, obtained by a reactive spray-drying process, where a liquid phase A, which comprises inorganic cations, and a liquid phase B, which comprises anions which, with the inorganic cations, form a salt that is insoluble in the mixture of the liquid phases are sprayed together using at least one multi-substance nozzle, and where at least one hydrophobic active ingredient is present in dissolved form in at least one liquid spraying phase, and where the salt formed from the cations of phase A and the anions of phase B has a solubility of less than 0.02 mol/l in the neutral aqueous medium.

    Abstract translation: 一种复合材料，其包含在无定形盐基质中的至少一种无定形疏水性活性成分，其在中性水性介质中的溶解度小于0.02mol / l，通过反应性喷雾干燥方法获得，其中液相A包含无机 阳离子和液相B，其包含与无机阳离子形成不溶于液相混合物的盐的阴离子，其使用至少一种多物质喷嘴喷射在一起，并且其中至少一种疏水性活性物质 成分以溶解形式存在于至少一个液体喷雾相中，其中由A相的阳离子形成的盐和B相的阴离子在中性水性介质中的溶解度小于0.02mol / l。

    COMPOSITION OF MICROCAPSULES WITH A SILICA SHELL AND A METHOD FOR THEIR PREPARATION
    3.
    发明申请
    COMPOSITION OF MICROCAPSULES WITH A SILICA SHELL AND A METHOD FOR THEIR PREPARATION 审中-公开
    微囊它们的制备硅胶外壳和方法组成

    公开(公告)号：US20140031463A1

    公开(公告)日：2014-01-30

    申请号：US13951871

    申请日：2013-07-26

    Applicant: BASF SE

    Inventor： Andreas Kempter ,  Uwe Seemann ,  Holger Kreusch ,  Heidrun Debus ,  Jing Dreher ,  Max Siebert

    IPC: C09K21/12

    CPC classification number: C09K21/12 ,  A23L27/72 ,  A61K8/11 ,  A61K8/25 ,  A61K9/501 ,  A61K2800/10 ,  A61K2800/412 ,  A61Q19/00 ,  B01J13/18 ,  Y10T428/2984

    Abstract: A process for the preparation of a microcapsule composition, wherein the shell of the microcapsules is essentially made of silica and the core comprises at least one lipophilic component, comprising the steps of: a) providing an aqueous dispersion comprising at least one lipophilic component (A) and b1) adding to the aqueous dispersion provided in step a) a water glass solution and an acid, or b2) adding to the aqueous dispersion provided in step a) a silicic acid solution and a base, wherein the addition is effected such that the pH of the mixture resulting during the addition of the water glass solution in step b1) or during the addition of silicic acid solution in step b2) is kept in a range of 6 to 9.

    Abstract translation: 一种用于制备微胶囊组合物，其中所述微胶囊的外壳基本上由二氧化硅和所述芯包含至少一种亲脂性组分，其包括以下步骤：a）提供包含至少一种亲脂性组分的水分散体（A ）和B1）向在步骤提供的水分散体）水玻璃溶液和酸，或b2）中加入到步骤a中提供的水分散液）硅酸溶液和碱，其中所述添加是实现使得 加入在步骤b1的水玻璃溶液的过程中）或添加在步骤b2硅酸溶液）中得到的混合物的pH值保持在范围的为6〜9。

    Production Of Inorganic-Organic Composite Materials By Reactive Spray-Drying
    4.
    发明申请
    Production Of Inorganic-Organic Composite Materials By Reactive Spray-Drying 有权
    通过反应性喷雾干燥生产无机 - 有机复合材料

    公开(公告)号：US20140228334A1

    公开(公告)日：2014-08-14

    申请号：US14175635

    申请日：2014-02-07

    Applicant: BASF SE

    Inventor： Andreas Kempter ,  Max Siebert ,  Heidrun Debus

    IPC: A61J3/02

    CPC classification number: A61K9/1682 ,  A61J3/005 ,  A61J3/02 ,  A61K9/143 ,  A61K9/145 ,  A61K9/1611 ,  A61K9/1617 ,  A61K31/192 ,  A61K31/415 ,  A61K31/496 ,  A61K31/565 ,  A61K31/58 ,  B01D1/18 ,  B01J2/04

    Abstract: Process for producing composite materials by reactive spray-drying, where a liquid phase A, which comprises inorganic cations, and a liquid phase B, which comprises anions which, with the inorganic cations, form a salt that is insoluble in the mixture of the liquid phases are sprayed together using at least one multi-substance nozzle, and where at least one hydrophobic active ingredient is present in dissolved form in at least one liquid spraying phase, and where the salt formed from the cations of phase A and the anions of phase B has a solubility of less than 0.02 mol/l in the neutral aqueous medium.

    Abstract translation: 通过反应性喷雾干燥制备复合材料的方法，其中包含无机阳离子的液相A和液相B，其包含阴离子，其与无机阳离子形成不溶于液体混合物的盐 使用至少一种多物质喷嘴将相分散在一起，并且其中至少一种疏水活性成分以溶解的形式存在于至少一个液体喷射相中，并且其中由相A的阳离子和相的阴离子形成的盐 B在中性水性介质中的溶解度小于0.02mol / l。

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