公开(公告)号：US09725704B2

公开(公告)日：2017-08-08

申请号：US14374556

申请日：2013-01-29

Applicant: BASF SE

Inventor： Tobias Kueppers ,  Victoria Steffen ,  Renee Charlott Eichstadt ,  Stefan Evers ,  Karl-Heinz Maurer ,  Johannes Bongaerts ,  Hendrik Hellmuth ,  Thomas Weber ,  Timothy O'Connell

IPC: C12N9/26 ,  C12N9/50 ,  C12N1/20 ,  C12N15/74 ,  C12P21/06 ,  C12P19/34 ,  C12N15/75 ,  C12P21/02 ,  C12N9/00 ,  C12N9/54

CPC classification number: C12N9/2411 ,  C12N9/00 ,  C12N9/2414 ,  C12N9/50 ,  C12N9/54 ,  C12N15/75 ,  C12P21/02

Abstract: In a microbial fermentation, the aim is to increase the product yield of protein. This is achieved by a method in which an expression construct is introduced into a microorganism of the species Bacillus pumilus which comprises a promoter and a nucleic acid coding for the protein, and the protein is expressed in said expression construct.

公开(公告)号：US20140370569A1

公开(公告)日：2014-12-18

申请号：US14374556

申请日：2013-01-29

Applicant: BASF SE

Inventor： Tobias Kueppers ,  Victoria Steffen ,  Renee Charlott Eichstadt ,  Stefan Evers ,  Karl-Heinz Maurer ,  Johannes Bongaerts ,  Hendrik Hellmuth ,  Thomas Weber ,  Timothy O'Connell

IPC: C12N9/26 ,  C12N9/50

CPC classification number: C12N9/2411 ,  C12N9/00 ,  C12N9/2414 ,  C12N9/50 ,  C12N9/54 ,  C12N15/75 ,  C12P21/02

Abstract: In a microbial fermentation, the aim is to increase the product yield of protein. This is achieved by a method in which an expression construct is introduced into a microorganism of the species Bacillus pumilus which comprises a promoter and a nucleic acid coding for the protein, and the protein is expressed in said expression construct.

Abstract translation: 在微生物发酵中，目的是提高蛋白质的产率。 这是通过一种方法实现的，其中将表达构建体引入到包含启动子和编码该蛋白质的核酸的物种短小芽孢杆菌的微生物中，并且所述蛋白质在所述表达构建体中表达。