公开(公告)号：US10781176B2

公开(公告)日：2020-09-22

申请号：US15569528

申请日：2016-04-26

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Wahed Ahmed Moradi ,  Günter Schlegel ,  Albert Schnatterer ,  Frank Volz

IPC: C07D213/61 ,  C07D213/40

Abstract: The present invention relates to novel processes for the preparation of substituted pyridyl-methylbenzamide derivatives of formula (I), in particular 2,6-dichloro-N-{[3-chloro-5-(trifluoromethyl)-2-pyridyl]methyl}benzamide (Fluopicolide), and for the catalytic hydrogenation of substituted cyanopyridine derivatives, in particular 3-chloro-2-cyano-5-trifluoromethylpyridine [=Py-CN] to the corresponding substituted 2-methylaminopyridine derivatives, in particular 2-aminomethyl-3-chloro-5-trifluoromethylpyridine [=Py-methylamine] or salts thereof in the presence of metal catalysts such as in particular palladium catalysts, catalytic modifiers and acids.

公开(公告)号：US10196410B2

公开(公告)日：2019-02-05

申请号：US15756174

申请日：2016-08-29

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Hans-Joachim Ressel ,  Kilian Tellmann ,  Mark James Ford ,  Martin Littmann ,  Günter Schlegel

IPC: C07F9/32 ,  A01N57/18

Abstract: The present invention primarily relates to a process for producing certain phosphorus-containing cyanohydrin esters of formula (I) and the use thereof for producing glufosinate/glufosinate salts. The present invention further relates to a process for producing glufosinate/glufosinate salts.

公开(公告)号：US10647674B2

公开(公告)日：2020-05-12

申请号：US15569528

申请日：2016-04-26

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Wahed Ahmed Moradi ,  Günter Schlegel ,  Albert Schnatterer ,  Frank Volz

IPC: C07D213/61 ,  C07D213/40

Abstract: The present invention relates to novel processes for the preparation of substituted pyridyl-methylbenzamide derivatives of formula (I), in particular 2,6-dichloro-N-{[3-chloro-5-(trifluoromethyl)-2-pyridyl]methyl}benzamide (Fluopicolide), and for the catalytic hydrogenation of substituted cyanopyridine derivatives, in particular 3-chloro-2-cyano-5-trifluoromethylpyridine [=Py-CN] to the corresponding substituted 2-methylaminopyridine derivatives, in particular 2-aminomethyl-3-chloro-5-trifluoromethylpyridine [=Py-methylamine] or salts thereof in the presence of metal catalysts such as in particular palladium catalysts, catalytic modifiers and acids.

公开(公告)号：US10316048B2

公开(公告)日：2019-06-11

申请号：US15756356

申请日：2016-08-30

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Hans-Joachim Ressel ,  Kilian Tellmann ,  Mark James Ford ,  Martin Littmann ,  Günter Schlegel

IPC: C07F9/32 ,  C07F9/30

Abstract: The present invention primarily relates to a process for producing certain phosphorus-containing cyanohydrin esters of formula (I) and the use thereof for producing glufosinate/glufosinate salts. The present invention further relates to a process for producing glufosinate/glufosinate salts.

公开(公告)号：US10414730B2

公开(公告)日：2019-09-17

申请号：US15969633

申请日：2018-05-02

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Wahed Ahmed Moradi ,  Thomas Himmler ,  Thomas Norbert Müller ,  Albert Schnatterer ,  Günter Schlegel

IPC: C07D213/56 ,  C07D213/89 ,  C07D213/38 ,  C07D213/57

Abstract: The present invention relates to a novel catalytic hydrogenation of substituted 2-methyl cyanopyridyl derivatives, in particular 3-chloro-5-(trifluoromethyl)pyridin-2-yl]acetonitrile [=Py-CN] to substituted 2-ethylaminopyridine derivatives, in particular 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethanamine [=Py-ethanamine] or salts thereof in the presence of metal catalysts, in particular palladium catalysts.

公开(公告)号：US20180244621A1

公开(公告)日：2018-08-30

申请号：US15969633

申请日：2018-05-02

Applicant: Bayer Cropscience Aktiengesellschaft

Inventor： Wahed Ahmed Moradi ,  Thomas Himmler ,  Thomas Norbert Müller ,  Albert Schnatterer ,  Günter Schlegel

IPC: C07D213/56 ,  C07D213/89 ,  C07D213/38 ,  C07D213/57

CPC classification number: C07D213/56 ,  C07D213/38 ,  C07D213/57 ,  C07D213/89

Abstract: The present invention relates to a novel catalytic hydrogenation of substituted 2-methyl cyanopyridyl derivatives, in particular 3-chloro-5-(trifluoromethyl)pyridin-2-yl]acetonitrile [=Py-CN] to substituted 2-ethylaminopyridine derivatives, in particular 2-[3-chloro-5-(trifluoromethyl)pyridin-2-yl]ethanamine [=Py-ethanamine] or salts thereof in the presence of metal catalysts, in particular palladium catalysts.

公开(公告)号：US09670135B2

公开(公告)日：2017-06-06

申请号：US15103110

申请日：2014-12-08

Applicant: BAYER CROPSCIENCE AKTIENGESELLSCHAFT

Inventor： Johann Seeba ,  Günter Schlegel ,  Martin Littmann ,  Rafael Warsitz ,  Mark James Ford

IPC: C07C209/08 ,  C07C209/04 ,  C07C209/84 ,  C07C209/14

CPC classification number: C07C209/08 ,  C07C209/04 ,  C07C209/14 ,  C07C209/84 ,  C07C211/29

Abstract: The present invention relates to a novel process for preparing halogenated di-substituted benzylamines, particularly halogenated dialkylbenzylamines.