公开(公告)号：US09971138B2

公开(公告)日：2018-05-15

申请号：US14262559

申请日：2014-04-25

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Michael Griffin ,  Daniel Yue Man Chu ,  Tom McCollum

IPC: G02B21/06 ,  G02B21/12 ,  G02B21/16 ,  G02B21/24 ,  G02B21/36

CPC classification number: G02B21/06 ,  G02B21/125 ,  G02B21/16 ,  G02B21/24 ,  G02B21/365

Abstract: A system, apparatus and method for using modular microscopes is disclosed. Connecting the housings of the individual microscope modules provide the structural framework of the modular microscope. Furthermore, the modular microscope can include specialized software, the distribution and use of which can be controlled using security keys or identifiers stored on one or more of the microscope modules. The security keys and identifiers can be based on calibration data associated with the physical, electrical, or optical properties of one of more of the modules. The illumination modules disclosed provide for selectable wavelengths and controllable levels of output illumination for both bright field and dark field illumination.

公开(公告)号：US20140327349A1

公开(公告)日：2014-11-06

申请号：US14266501

申请日：2014-04-30

Applicant: BIO-RAD LABORATORIES, INC.

Inventor： Jeffry M. Ceremony ,  Tom McCollum

IPC: B01L7/00

CPC classification number: B01L7/52 ,  B01L2300/041 ,  B01L2300/046 ,  B01L2300/0829 ,  B01L2300/1827

Abstract: A drawer apparatus having a drawer chassis and a drawer adapted to move relative to the drawer chassis from a closed position to an open position. The drawer has first and second lateral sides. A lid assembly is moveable from an upward position to a downward position relative to the drawer chassis. The lid assembly has first and second roller members. A first lever arm is rotatable about a first pivot on the first lateral side. The first lever arm has a first surface for moveably engaging with the first roller member. A second lever arm is rotatable about a second pivot on the second lateral side. The second lever arm has a second surface for moveably engaging with the second roller. A handle connects the first and second lever arms. The handle is adapted to move the first and second lever arms respectively about the first and second pivots to move the lid assembly from the downward position to the upward position.

Abstract translation: 一种抽屉设备，其具有抽屉底盘和适于相对于抽屉底盘从关闭位置移动到打开位置的抽屉。 抽屉有第一和第二侧面。 盖组件可相对于抽屉底座从向上位置移动到向下位置。 盖组件具有第一和第二辊构件。 第一杠杆臂可围绕第一侧面的第一枢轴转动。 第一杠杆臂具有用于与第一辊构件可移动地接合的第一表面。 第二杠杆臂可绕第二横向侧上的第二枢轴旋转。 第二杠杆臂具有用于与第二辊可动地接合的第二表面。 手柄连接第一和第二杠杆臂。 手柄适于分别围绕第一和第二枢轴移动第一和第二杠杆臂，以将盖组件从向下位置移动到向上位置。

公开(公告)号：US20140293412A1

公开(公告)日：2014-10-02

申请号：US14262559

申请日：2014-04-25

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Michael Griffin ,  Daniel Yue Man Chu ,  Tom McCollum

IPC: G02B21/06

CPC classification number: G02B21/06 ,  G02B21/125 ,  G02B21/16 ,  G02B21/24 ,  G02B21/365

Abstract: A system, apparatus and method for using modular microscopes is disclosed. Connecting the housings of the individual microscope modules provide the structural framework of the modular microscope. Furthermore, the modular microscope can include specialized software, the distribution and use of which can be controlled using security keys or identifiers stored on one or more of the microscope modules. The security keys and identifiers can be based on calibration data associated with the physical, electrical, or optical properties of one of more of the modules. The illumination modules disclosed provide for selectable wavelengths and controllable levels of output illumination for both bright field and dark field illumination.

Abstract translation: 公开了一种使用模块显微镜的系统，装置和方法。 连接各个显微镜模块的外壳提供了模块化显微镜的结构框架。 此外，模块化显微镜可以包括专门的软件，可以使用存储在一个或多个显微镜模块上的安全密钥或标识符来控制其分布和使用。 安全密钥和标识符可以基于与多个模块之一的物理，电或光学特性相关联的校准数据。 所公开的照明模块为亮场和暗场照明提供了可选择的波长和输出照明的可控电平。

公开(公告)号：US09850517B2

公开(公告)日：2017-12-26

申请号：US14039682

申请日：2013-09-27

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Tom McCollum ,  Paul Patt ,  Frank Shen ,  Daniel Y. Chu ,  Don Flory ,  Mike Griffin ,  Xin Heng ,  Eli Hefner

IPC: C12Q1/06 ,  G01N15/14 ,  G02B21/34 ,  G02B21/00

CPC classification number: C12Q1/06 ,  G01N15/1434 ,  G02B21/0008 ,  G02B21/34

Abstract: Biological cells in a liquid suspension are counted in an automated cell counter that focuses an image of the suspension on a digital imaging sensor that contains at least 4,000,000 pixels each having an area of 2×2 μm or less and that images a field of view of at least 3 mm2. The sensor enables the counter to compress the optical components into an optical path of less than 20 cm in height when arranged vertically with no changes in direction of the optical path as a whole, and the entire instrument has a footprint of less than 300 cm2. Activation of the light source, automated focusing of the sensor image, and digital cell counting are all initiated by the simple insertion of the sample holder into the instrument. The suspension is placed in a sample chamber in the form of a slide that is shaped to ensure proper orientation of the slide in the cell counter.