公开(公告)号：US11808697B2

公开(公告)日：2023-11-07

申请号：US17877680

申请日：2022-07-29

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Evan Thrush ,  Steven Swihart ,  William Strong ,  Trey Marlowe ,  Li Lu

IPC: G01N21/31 ,  G01N21/3577 ,  G01N21/3563

CPC classification number: G01N21/3103 ,  G01N21/3563 ,  G01N21/3577 ,  G01N2021/3572 ,  G01N2201/0686

Abstract: Systems for protein quantitation using a Fabry-Perot interferometer. In one arrangement, a quantitation device includes an infrared source, a sample holder, and a Fabry-Perot interferometer positioned to receive infrared radiation from the source passing through a sample on the sample holder. A band pass optical filter sets the working range of the interferometer, and radiation exiting the interferometer falls on a detector that produces a signal indicating the intensity of the received radiation. A controller causes the interferometer to be tuned to a number of different resonance wavelengths and receives the intensity signals, for determination of an absorbance spectrum.

公开(公告)号：US20190107484A1

公开(公告)日：2019-04-11

申请号：US16151732

申请日：2018-10-04

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Evan Thrush ,  Steven Swihart ,  William Strong ,  Trey Marlowe

IPC: G01N21/31 ,  G01N21/3577 ,  G01N21/3563

Abstract: Systems for protein quantitation using a Fabry-Perot interferometer. In one arrangement, a quantitation device includes an infrared source, a sample holder, and a Fabry-Perot interferometer positioned to receive infrared radiation from the source passing through a sample on the sample holder. A band pass optical filter sets the working range of the interferometer, and radiation exiting the interferometer falls on a detector that produces a signal indicating the intensity of the received radiation. A controller causes the interferometer to be tuned to a number of different resonance wavelengths and receives the intensity signals, for determination of an absorbance spectrum.

公开(公告)号：US11435285B2

公开(公告)日：2022-09-06

申请号：US17199312

申请日：2021-03-11

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Evan Thrush ,  Steven Swihart ,  William Strong ,  Trey Marlowe ,  Li Lu

IPC: G01N21/31 ,  G01N21/3577 ,  G01N21/3563

Abstract: Systems for protein quantitation using a Fabry-Perot interferometer. In one arrangement, a quantitation device includes an infrared source, a sample holder, and a Fabry-Perot interferometer positioned to receive infrared radiation from the source passing through a sample on the sample holder. A band pass optical filter sets the working range of the interferometer, and radiation exiting the interferometer falls on a detector that produces a signal indicating the intensity of the received radiation. A controller causes the interferometer to be tuned to a number of different resonance wavelengths and receives the intensity signals, for determination of an absorbance spectrum.

公开(公告)号：US10948403B2

公开(公告)日：2021-03-16

申请号：US16151732

申请日：2018-10-04

Applicant: Bio-Rad Laboratories, Inc.

Inventor： Evan Thrush ,  Steven Swihart ,  William Strong ,  Trey Marlowe ,  Li Lu

IPC: G01N21/31 ,  G01N21/3577 ,  G01N21/3563

Abstract: Systems for protein quantitation using a Fabry-Perot interferometer. In one arrangement, a quantitation device includes an infrared source, a sample holder, and a Fabry-Perot interferometer positioned to receive infrared radiation from the source passing through a sample on the sample holder. A band pass optical filter sets the working range of the interferometer, and radiation exiting the interferometer falls on a detector that produces a signal indicating the intensity of the received radiation. A controller causes the interferometer to be tuned to a number of different resonance wavelengths and receives the intensity signals, for determination of an absorbance spectrum.

公开(公告)号：US10788423B2

公开(公告)日：2020-09-29

申请号：US15471264

申请日：2017-03-28

Applicant: Bio-Rad Laboratories, Inc.

Inventor： John Barich ,  Renee Lemaire-Adkins ,  David Neaz ,  Ariel Notcovich ,  Paul Patt ,  Ryan Short ,  Steven Swihart ,  Evan Thrush ,  Trey Marlowe

IPC: H04N5/357 ,  H04N5/361 ,  G01N21/63 ,  G01N21/64 ,  H04N5/262 ,  H04N5/349 ,  G01N27/447 ,  H04N5/335 ,  G02B21/06

Abstract: Analyte arrays such as solutes in a slab-shaped gel following electrophoresis, and particularly arrays that are in excess of 3 cm square and up to 25 cm square and higher, are imaged at distances of 5 cm or less by either forming sub-images of the entire array and stitching together the sub-images by computer-based stitching technology, or by using an array of thin-film photoresponsive elements that is coextensive with the analyte array to form a single image of the array.

公开(公告)号：US10564098B2

公开(公告)日：2020-02-18

申请号：US14056162

申请日：2013-10-17

Applicant: Bio-Rad Laboratories, Inc.

Inventor： John Barich ,  Renee Lemaire-Adkins ,  David Neaz ,  Ariel Notcovich ,  Paul Patt ,  Ryan Short ,  Steven Swihart ,  Evan Thrush ,  Trey Marlowe

IPC: H04N5/361 ,  H04N5/357 ,  H04N5/335 ,  G01N21/64 ,  G01N21/63 ,  H04N5/262 ,  H04N5/349 ,  G01N27/447 ,  G02B21/06

Abstract: Analyte arrays such as solutes in a slab-shaped gel following electrophoresis, and particularly arrays that are in excess of 3 cm square and up to 25 cm square and higher, are imaged at distances of 5 cm or less by either forming sub-images of the entire array and stitching together the sub-images by computer-based stitching technology, or by using an array of thin-film photoresponsive elements that is coextensive with the analyte array to form a single image of the array.