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    Protein quantitation device
    1.
    发明授权
    Protein quantitation device 有权

    公开(公告)号：US11435285B2

    公开(公告)日：2022-09-06

    申请号：US17199312

    申请日：2021-03-11

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Evan Thrush ,  Steven Swihart ,  William Strong ,  Trey Marlowe ,  Li Lu

    IPC: G01N21/31 ,  G01N21/3577 ,  G01N21/3563

    Abstract: Systems for protein quantitation using a Fabry-Perot interferometer. In one arrangement, a quantitation device includes an infrared source, a sample holder, and a Fabry-Perot interferometer positioned to receive infrared radiation from the source passing through a sample on the sample holder. A band pass optical filter sets the working range of the interferometer, and radiation exiting the interferometer falls on a detector that produces a signal indicating the intensity of the received radiation. A controller causes the interferometer to be tuned to a number of different resonance wavelengths and receives the intensity signals, for determination of an absorbance spectrum.

    Digital imaging with masked pixels
    2.
    发明授权
    Digital imaging with masked pixels 有权

    公开(公告)号：US10326952B2

    公开(公告)日：2019-06-18

    申请号：US15675494

    申请日：2017-08-11

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Boaz Ran ,  Steve Swihart ,  Evan Thrush ,  Itay Barak

    IPC: H04N5/365 ,  H04N5/361

    Abstract: In one application, an imaging device includes an image sensor having an array of pixels, and a mask coupled with the image sensor. The mask is configured to darken a plurality of isolated pixels or groups of pixels interspersed within the array of pixels. The imaging device also includes a processor coupled with the image sensor and configured to receive image data from the image sensor, and determine a dark current fixed pattern noise based on the image data received from the plurality of darkened pixels or groups of pixels.

    Double Fold Optics
    3.
    发明申请
    Double Fold Optics 有权
    双折光学

    公开(公告)号：US20150070483A1

    公开(公告)日：2015-03-12

    申请号：US14477253

    申请日：2014-09-04

    Applicant: Bio-Rad Laboratories, Inc., LSG-LSD Division

    Inventor： Evan Thrush ,  Evelio Perez ,  Steve Swihart

    IPC: G02B21/36 ,  G02B21/00 ,  G02B21/04

    CPC classification number: G02B21/361 ,  G01N21/00 ,  G01N21/76 ,  G02B17/023 ,  G02B21/0008 ,  G03B15/00 ,  G03B17/17

    Abstract: An imaging assembly for the viewing, imaging, and analysis of biological, chemical, and/or biochemical samples in gels or other substrates, in which an adjustable camera and lens module, a reflex mirror, and a focal plane mirror, are configured to bend or fold an optical path in order to image a target region, and where the optical path can be reflected along non-orthogonal angles. The imaging assembly is configured to reduce the overall size of the imaging apparatus due to the angles at which the mirrors and camera and lens assembly are positioned relative to each other, which allows for the imaging of relatively larger samples in the target region.

    Abstract translation: 用于观察，成像和分析凝胶或其它基底中的生物，化学和/或生化样品的成像组件，其中可调节的相机和透镜模块，反射镜和焦平面镜配置成弯曲 或折叠光路以便对目标区域进行成像，并且其中可以沿非正交角度反射光路。 成像组件被配置为由于反射镜和相机和透镜组件相对于彼此定位的角度而减小成像装置的总体尺寸，这允许在目标区域中对相对较大的样本进行成像。

    Protein quantitation device
    4.
    发明授权
    Protein quantitation device 有权

    公开(公告)号：US10948403B2

    公开(公告)日：2021-03-16

    申请号：US16151732

    申请日：2018-10-04

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Evan Thrush ,  Steven Swihart ,  William Strong ,  Trey Marlowe ,  Li Lu

    IPC: G01N21/31 ,  G01N21/3577 ,  G01N21/3563

    Abstract: Systems for protein quantitation using a Fabry-Perot interferometer. In one arrangement, a quantitation device includes an infrared source, a sample holder, and a Fabry-Perot interferometer positioned to receive infrared radiation from the source passing through a sample on the sample holder. A band pass optical filter sets the working range of the interferometer, and radiation exiting the interferometer falls on a detector that produces a signal indicating the intensity of the received radiation. A controller causes the interferometer to be tuned to a number of different resonance wavelengths and receives the intensity signals, for determination of an absorbance spectrum.

    Double fold optics
    7.
    发明授权
    Double fold optics 有权
    双折光学

    公开(公告)号：US09310600B2

    公开(公告)日：2016-04-12

    申请号：US14477253

    申请日：2014-09-04

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Evan Thrush ,  Evelio Perez ,  Steve Swihart

    IPC: G03B15/00 ,  G02B21/36 ,  G02B21/00 ,  G01N21/00 ,  G02B17/02

    CPC classification number: G02B21/361 ,  G01N21/00 ,  G01N21/76 ,  G02B17/023 ,  G02B21/0008 ,  G03B15/00 ,  G03B17/17

    Abstract: An imaging assembly for the viewing, imaging, and analysis of biological, chemical, and/or biochemical samples in gels or other substrates, in which an adjustable camera and lens module, a reflex mirror, and a focal plane mirror, are configured to bend or fold an optical path in order to image a target region, and where the optical path can be reflected along non-orthogonal angles. The imaging assembly is configured to reduce the overall size of the imaging apparatus due to the angles at which the mirrors and camera and lens assembly are positioned relative to each other, which allows for the imaging of relatively larger samples in the target region.

    Abstract translation: 用于观察，成像和分析凝胶或其它基底中的生物，化学和/或生化样品的成像组件，其中可调节的相机和透镜模块，反射镜和焦平面镜配置成弯曲 或折叠光路以便对目标区域进行成像，并且其中可以沿非正交角度反射光路。 成像组件被配置为由于反射镜和相机和透镜组件相对于彼此定位的角度而减小成像装置的总体尺寸，这允许在目标区域中对相对较大的样本进行成像。

    ELECTRONIC COMPONENT ASSEMBLY WITH THERMALLY CONDUCTIVE STRUCTURES FOR IMAGE SENSORS
    9.
    发明申请
    ELECTRONIC COMPONENT ASSEMBLY WITH THERMALLY CONDUCTIVE STRUCTURES FOR IMAGE SENSORS 有权

    公开(公告)号：US20210176386A1

    公开(公告)日：2021-06-10

    申请号：US17108672

    申请日：2020-12-01

    Applicant: BIO-RAD LABORATORIES, INC.

    Inventor： Stephen Swihart ,  Li Lu ,  Wade Jameson ,  Evan Thrush ,  Michael Griffin ,  Evelio Perez

    IPC: H04N5/225 ,  H05K7/20

    Abstract: An electronic component assembly having thermal pads with thermal vias coupling an image sensor and a camera board fab is provided for heat dissipation. The electronic component assembly can include: a circuit board having at least one thermal pad disposed on a top surface of the circuit board; and an image sensor disposed on the top surface of the circuit board, having at least one conductive pad disposed at at least one corner of the image sensor. The at least one thermal pad is coupled to the at least one conductive pad of the image sensor and the at least one thermal pad is formed with a plurality of first thermal vias penetrating the thermal pad and the circuit board for transfer of heat of the image sensor.

    PROTEIN QUANTITATION DEVICE
    10.
    发明申请
    PROTEIN QUANTITATION DEVICE 审中-公开

    公开(公告)号：US20190107484A1

    公开(公告)日：2019-04-11

    申请号：US16151732

    申请日：2018-10-04

    Applicant: Bio-Rad Laboratories, Inc.

    Inventor： Evan Thrush ,  Steven Swihart ,  William Strong ,  Trey Marlowe

    IPC: G01N21/31 ,  G01N21/3577 ,  G01N21/3563

    Abstract: Systems for protein quantitation using a Fabry-Perot interferometer. In one arrangement, a quantitation device includes an infrared source, a sample holder, and a Fabry-Perot interferometer positioned to receive infrared radiation from the source passing through a sample on the sample holder. A band pass optical filter sets the working range of the interferometer, and radiation exiting the interferometer falls on a detector that produces a signal indicating the intensity of the received radiation. A controller causes the interferometer to be tuned to a number of different resonance wavelengths and receives the intensity signals, for determination of an absorbance spectrum.

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